Protein: VPS52
Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein)

Gene: VPS52
Organism: Homo sapiens
Interactions: 192
UniProt ID: Q8N1B4

Gene Ontology (top 5):
GO:0000938 - GARP complex
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006605 - protein targeting
GO:0006896 - Golgi to vacuole transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1230716

RNF41
E3 ubiquitin-protein ligase NRDP1

8

5

Small-scale

0.757

High

1230698

VPS50
Syndetin

6

6

Small-scale

0.738

High

770634

TXLNA
Alpha-taxilin

4

2

High-throughput

0.704

High

1121528

EIPR1
EARP and GARP complex-interacting protein 1

4

2

Small-scale

0.694

High

1230740

VPS51
Vacuolar protein sorting-associated protein 51 homolog

4

7

Small-scale

0.690

High

1137629

VPS53
Vacuolar protein sorting-associated protein 53 homolog

4

4

Small-scale

0.683

High

271141

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

3

1

High-throughput

0.675

High

1230749

TRAF6
TNF receptor-associated factor 6

3

4

High-throughput

0.675

High

1230751

VATD
V-type proton ATPase subunit D

3

2

High-throughput

0.675

High

726308

BASI
Basigin

3

1

High-throughput

0.667

High

591925

RAB4A
Ras-related protein Rab-4A

3

3

High-throughput

0.666

High

1230742

VPS28
Vacuolar protein sorting-associated protein 28 homolog

3

1

High-throughput

0.660

High

1230736

VPS54
Vacuolar protein sorting-associated protein 54

3

2

Small-scale

0.646

High

640539

DDX6
Probable ATP-dependent RNA helicase DDX6

3

0

High-throughput

0.646

High

1230686

GOGA1
Golgin subfamily A member 1

3

0

High-throughput

0.646

High

1230732

AIRIM
AFG2-interacting ribosome maturation factor

3

0

High-throughput

0.646

High

1230728

TB22B
TBC1 domain family member 22B

4

2

High-throughput

0.637

High

1230695

THA11
THAP domain-containing protein 11

2

1

High-throughput

0.633

High

875675

MFAP1
Microfibrillar-associated protein 1

3

1

High-throughput

0.616

High

1157421

PPR18
Phostensin

3

1

High-throughput

0.616

High

1223030

CC146
Coiled-coil domain-containing protein 146

3

2

High-throughput

0.616

High

1044869

AAMP
Angio-associated migratory cell protein

2

1

High-throughput

0.613

High

155038

NDC80
Kinetochore protein NDC80 homolog

2

1

High-throughput

0.606

High

895008

RAB4B
Ras-related protein Rab-4B

2

3

High-throughput

0.606

High

1160252

PKN3
Serine/threonine-protein kinase N3

2

1

High-throughput

0.606

High

1223063

CCD13
Coiled-coil domain-containing protein 13

2

2

High-throughput

0.606

High

1230670

TXLNB
Beta-taxilin

2

4

High-throughput

0.606

High

1230682

CCHCR
Coiled-coil alpha-helical rod protein 1

2

2

High-throughput

0.606

High

1230690

JKIP2
Janus kinase and microtubule-interacting protein 2

2

1

High-throughput

0.606

High

1230705

CDC5L
Cell division cycle 5-like protein

2

1

High-throughput

0.606

High

1230711

TRAF4
TNF receptor-associated factor 4

2

3

High-throughput

0.606

High

1230712

KIFC3
Kinesin-like protein KIFC3

2

3

High-throughput

0.606

High

1230733

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

2

1

High-throughput

0.606

High

907096

PRS8
26S proteasome regulatory subunit 8

2

0

High-throughput

0.602

High

1230739

ENOPH
Enolase-phosphatase E1

2

0

High-throughput

0.602

High

1076373

IKBB
NF-kappa-B inhibitor beta

2

0

High-throughput

0.601

High

1107899

F161A
Protein FAM161A

3

1

High-throughput

0.593

High

1230746

NINL
Ninein-like protein

2

1

High-throughput

0.584

High

208273

DCX
Neuronal migration protein doublecortin

2

0

High-throughput

0.580

High

447264

HXB5
Homeobox protein Hox-B5

2

0

High-throughput

0.580

High

880778

HDAC4
Histone deacetylase 4

2

0

High-throughput

0.580

High

1046888

BYST
Bystin

2

0

High-throughput

0.580

High

1230708

F110A
Protein FAM110A

2

0

High-throughput

0.580

High

1230720

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.580

High

1230725

CABP5
Calcium-binding protein 5

2

0

High-throughput

0.580

High

1230737

KLH42
Kelch-like protein 42

2

0

High-throughput

0.580

High

1230748

WASC3
WASH complex subunit 3

2

0

High-throughput

0.580

High

269446

STX11
Syntaxin-11

1

2

High-throughput

0.573

High

419002

TPM3
Tropomyosin alpha-3 chain

1

2

High-throughput

0.573

High

871436

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

High-throughput

0.573

High

1025172

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

1

High-throughput

0.573

High

1075208

TEAD4
Transcriptional enhancer factor TEF-3

2

1

High-throughput

0.559

High

246464

DTNB
Dystrobrevin beta

2

1

High-throughput

0.553

High

874303

GEM
GTP-binding protein GEM

2

2

High-throughput

0.553

High

989697

CDK18
Cyclin-dependent kinase 18

2

1

High-throughput

0.553

High

1198497

TBCD1
TBC1 domain family member 1

2

1

High-throughput

0.553

High

1230674

CC185
Coiled-coil domain-containing protein 185

2

2

High-throughput

0.553

High

1230679

CA216
UPF0500 protein C1orf216

2

1

High-throughput

0.553

High

1230680

ZN417
Zinc finger protein 417

2

1

High-throughput

0.553

High

1230681

LNX1
E3 ubiquitin-protein ligase LNX

2

1

High-throughput

0.553

High

1230701

F161B
Protein FAM161B

2

1

High-throughput

0.553

High

1230704

ZN587
Zinc finger protein 587

2

1

High-throughput

0.553

High

1230721

KIF9
Kinesin-like protein KIF9

2

4

High-throughput

0.553

High

1230731

DJC11
DnaJ homolog subfamily C member 11

2

1

High-throughput

0.553

High

1230673

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

0

High-throughput

0.549

High

1230689

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

0

High-throughput

0.549

High

1230693

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.549

High

1230719

SH24A
SH2 domain-containing protein 4A

1

0

High-throughput

0.549

High

160096

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.541

High

172110

GP182
G-protein coupled receptor 182

1

6

High-throughput

0.536

High

237989

EXOC3
Exocyst complex component 3

1

3

High-throughput

0.536

High

644717

NKG2D
NKG2-D type II integral membrane protein

1

2

High-throughput

0.536

High

1070143

RABE1
Rab GTPase-binding effector protein 1

1

3

High-throughput

0.536

High

1174383

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

1

High-throughput

0.536

High

1230707

CML1
Chemerin-like receptor 1

1

5

High-throughput

0.536

High

802147

NOP2
Probable 28S rRNA

1

1

High-throughput

0.523

High

1133627

SKT
Sickle tail protein homolog

1

1

High-throughput

0.523

High

647626

MK03
Mitogen-activated protein kinase 3

1

0

High-throughput

0.518

High

87390

C9JG97
Angio associated migratory cell protein

1

1

High-throughput

0.515

High

1230752

V9HW29
Kinesin-like protein

1

6

High-throughput

0.515

High

176236

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.513

High

801243

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

985360

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.513

High

1230684

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1230727

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.513

High

1230735

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.513

High

1230724

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

1

1

High-throughput

0.494

High

856416

EFNA4
Ephrin-A4

1

1

High-throughput

0.489

High

895675

CXCR4
C-X-C chemokine receptor type 4

1

4

High-throughput

0.489

High

1031005

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

4

High-throughput

0.489

High

1101728

CF184
Cilia- and flagella-associated protein 184

1

1

High-throughput

0.489

High

1230677

THAP8
THAP domain-containing protein 8

1

4

High-throughput

0.489

High

1230683

CLC2B
C-type lectin domain family 2 member B

1

2

High-throughput

0.489

High

1230700

ODAD1
Outer dynein arm-docking complex subunit 1

1

1

High-throughput

0.489

High

1230709

KXDL1
KxDL motif-containing protein 1

1

1

High-throughput

0.489

High

132330

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.486

High

702944

KINH
Kinesin-1 heavy chain

1

6

High-throughput

0.481

High

1230669

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

3

Small-scale

0.481

High

1230717

HEAT1
HEAT repeat-containing protein 1

1

1

High-throughput

0.481

High

1230718

RABE2
Rab GTPase-binding effector protein 2

1

3

High-throughput

0.481

High

162980

XPO1
Exportin-1

1

1

High-throughput

0.479

High

212926

STX6
Syntaxin-6

1

1

Small-scale

0.479

High

228026

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

261690

VAMP4
Vesicle-associated membrane protein 4

1

1

Small-scale

0.479

High

385153

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

894202

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.479

High

900677

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

925428

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

High-throughput

0.479

High

1071659

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.479

High

1073449

KS6A1
Ribosomal protein S6 kinase alpha-1

1

1

High-throughput

0.479

High

1230722

RHOF
Rho-related GTP-binding protein RhoF

1

5

High-throughput

0.479

High

1230726

DBLOH
Diablo IAP-binding mitochondrial protein

1

1

High-throughput

0.479

High

1230734

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1230738

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

88046

D3DUQ6
TEA domain family member 4 isoform 1

1

1

High-throughput

0.470

High

1122101

Q548N1
Vacuolar protein sorting-associated protein 28 homolog

1

1

High-throughput

0.470

High

1138394

Q5VU62
TPM3 protein

1

1

High-throughput

0.470

High

1160612

Q6P9G8
Family with sequence similarity 184, member A

1

1

High-throughput

0.470

High

1161999

Q6PJ05
V-type proton ATPase subunit D

1

2

High-throughput

0.470

High

1230672

Q8N5Z9
V-type proton ATPase subunit D

1

2

High-throughput

0.470

High

1230696

Q96ES5
HEAT repeat-containing protein 1

1

1

High-throughput

0.470

High

130984

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

262033

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

742391

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

1101159

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1188293

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1230691

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

1230692

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.458

High

1230743

SMC3
Structural maintenance of chromosomes protein 3

1

0

High-throughput

0.458

High

3249

A0A0S2Z4Q4
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.457

High

1230678

F184A
Protein FAM184A

1

1

High-throughput

0.439

High

164423

TRI66
Tripartite motif-containing protein 66

1

2

High-throughput

0.437

High

319261

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.437

High

347304

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.437

High

379604

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.437

High

553162

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

651665

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

720897

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

941149

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1170775

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1230685

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1230715

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1230741

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

3

High-throughput

0.417

High

1062764

FL2D
Pre-mRNA-splicing regulator WTAP

4

0

High-throughput

0.365

High

1135025

TSTD2
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

3

0

High-throughput

0.352

High

1185183

EPMIP
EPM2A-interacting protein 1

3

0

High-throughput

0.352

High

1230675

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

3

0

High-throughput

0.352

High

1230703

TSSK3
Testis-specific serine/threonine-protein kinase 3

3

0

High-throughput

0.352

High

1230706

THIOM
Thioredoxin, mitochondrial

3

0

High-throughput

0.352

High

596140

C4BPB
C4b-binding protein beta chain

3

0

High-throughput

0.347

High

1230697

BORC6
BLOC-1-related complex subunit 6

3

0

High-throughput

0.340

High

771215

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.328

High

1081478

CNGA3
Cyclic nucleotide-gated channel alpha-3

2

0

High-throughput

0.328

High

1030732

SLAF1
Signaling lymphocytic activation molecule

2

0

High-throughput

0.318

High

1230694

FAF2
FAS-associated factor 2

2

0

High-throughput

0.318

High

987440

MTG8
Protein CBFA2T1

2

0

High-throughput

0.316

High

1048551

VEZF1
Vascular endothelial zinc finger 1

2

0

High-throughput

0.316

High

1102757

CCD57
Coiled-coil domain-containing protein 57

2

0

High-throughput

0.316

High

1103224

C19L2
CWF19-like protein 2

2

0

High-throughput

0.316

High

1120611

ZC21C
Zinc finger C2HC domain-containing protein 1C

2

0

High-throughput

0.316

High

1122033

CTSRT
Cation channel sperm-associated targeting subunit tau

2

0

High-throughput

0.316

High

1147845

C102B
Coiled-coil domain-containing protein 102B

2

0

High-throughput

0.316

High

1185430

OTU6A
OTU domain-containing protein 6A

2

0

High-throughput

0.316

High

1203351

NR2CA
Nuclear receptor 2C2-associated protein

2

0

High-throughput

0.316

High

1205199

CD20B
Cell division cycle protein 20 homolog B

2

0

High-throughput

0.316

High

1217930

Q8IVT4
Hypothetical MGC50722

2

0

High-throughput

0.316

High

1223459

CF206
Cilia- and flagella-associated protein 206

2

0

High-throughput

0.316

High

1230687

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.316

High

1230688

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

2

0

High-throughput

0.316

High

1230699

CEP19
Centrosomal protein of 19 kDa

2

0

High-throughput

0.316

High

1230713

SCNM1
Sodium channel modifier 1

2

0

High-throughput

0.316

High

1230714

RM01
Large ribosomal subunit protein uL1m

2

0

High-throughput

0.316

High

1230729

T11L1
T-complex protein 11-like protein 1

2

0

High-throughput

0.316

High

1230744

FA50B
Protein FAM50B

2

0

High-throughput

0.316

High

903752

LMO4
LIM domain transcription factor LMO4

1

0

High-throughput

0.299

High

1144707

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

0

High-throughput

0.299

High

1159980

KLC3
Kinesin light chain 3

1

0

High-throughput

0.299

High

1230702

ZMAT2
Zinc finger matrin-type protein 2

1

0

High-throughput

0.299

High

1230747

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.299

High

1230710

PIMRE
Protein PIMREG

1

0

High-throughput

0.282

High

519413

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

1

0

High-throughput

0.279

Low

1102599

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1230723

SACA1
Sperm acrosome membrane-associated protein 1

1

0

High-throughput

0.279

Low

1230745

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.279

Low

1230750

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.279

Low

1230671

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

824181

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1165749

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1188547

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1230676

ARL10
ADP-ribosylation factor-like protein 10

1

0

High-throughput

0.249

Low

1230730

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024