Protein: PPLA
Cardiac phospholamban (PLB)

Gene: PPLA, PLN
Organism: Homo sapiens
Interactions: 70
UniProt ID: P26678

Gene Ontology (top 5):
GO:0001675 - acrosome assembly
GO:0002026 - regulation of the force of heart contraction
GO:0004857 - enzyme inhibitor activity
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

561500

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

5

3

Small-scale

0.909

High

163750

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

3

3

Small-scale

0.827

High

644390

DMPK
Myotonin-protein kinase

1

1

Small-scale

0.785

High

644415

EDA
Ectodysplasin-A

6

0

High-throughput

0.710

High

644384

PPLA
Cardiac phospholamban

1

1

Small-scale

0.647

High

644423

B2L13
Bcl-2-like protein 13

3

0

High-throughput

0.646

High

157529

MGST3
Glutathione S-transferase 3, mitochondrial

2

1

High-throughput

0.606

High

426812

ASGR2
Asialoglycoprotein receptor 2

2

1

High-throughput

0.606

High

644420

MGST2
Microsomal glutathione S-transferase 2

2

1

High-throughput

0.606

High

644433

TM45A
Transmembrane protein 45A

2

1

High-throughput

0.606

High

644434

CLC2D
C-type lectin domain family 2 member D

2

1

High-throughput

0.606

High

243173

G37L1
G-protein coupled receptor 37-like 1

2

0

High-throughput

0.580

High

306981

RTN3
Reticulon-3

2

0

High-throughput

0.580

High

314421

NPT2B
Sodium-dependent phosphate transport protein 2B

2

0

High-throughput

0.580

High

644385

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

0

High-throughput

0.580

High

644387

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

0

High-throughput

0.580

High

644391

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.580

High

644394

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

0

High-throughput

0.580

High

644395

UT2
Urea transporter 2

2

0

High-throughput

0.580

High

644399

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.580

High

644403

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.580

High

644404

TM205
Transmembrane protein 205

2

0

High-throughput

0.580

High

644405

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

0

High-throughput

0.580

High

644408

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

0

High-throughput

0.580

High

644409

LSME2
Leucine-rich single-pass membrane protein 2

2

0

High-throughput

0.580

High

644410

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.580

High

644411

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.580

High

644414

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

644422

T106C
Transmembrane protein 106C

2

0

High-throughput

0.580

High

644424

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.580

High

644426

MFF
Mitochondrial fission factor

2

0

High-throughput

0.580

High

644427

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.580

High

644428

SACA1
Sperm acrosome membrane-associated protein 1

2

0

High-throughput

0.580

High

216672

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.573

High

644418

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

1

1

High-throughput

0.573

High

134993

SARCO
Sarcolipin

2

0

Small-scale

0.559

High

644386

STX2
Syntaxin-2

2

1

High-throughput

0.553

High

644388

CXA8
Gap junction alpha-8 protein

2

1

High-throughput

0.553

High

644396

STX1A
Syntaxin-1A

2

1

High-throughput

0.553

High

644417

TM45B
Transmembrane protein 45B

2

1

High-throughput

0.553

High

3267

A0A0S2Z4U3
Syndecan

1

1

High-throughput

0.515

High

253691

SDC3
Syndecan-3

1

1

High-throughput

0.481

High

644397

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

0

Small-scale

0.480

High

644401

TMM31
Transmembrane protein 31

1

0

High-throughput

0.460

High

644435

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.460

High

644392

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

644419

VMP1
Vacuole membrane protein 1

1

0

Small-scale

0.458

High

644402

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

3

0

High-throughput

0.348

High

175601

VA0E1
V-type proton ATPase subunit e 1

2

0

High-throughput

0.316

High

177822

TMPS2
Transmembrane protease serine 2

2

0

High-throughput

0.316

High

315109

CLD7
Claudin-7

2

0

High-throughput

0.316

High

554270

MUC1
Mucin-1

2

0

High-throughput

0.316

High

583859

CD53
Leukocyte surface antigen CD53

2

0

High-throughput

0.316

High

644398

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

644400

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

644406

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

644407

T179B
Transmembrane protein 179B

2

0

High-throughput

0.316

High

644412

PLPR1
Phospholipid phosphatase-related protein type 1

2

0

High-throughput

0.316

High

644413

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.316

High

644425

MS4A7
Membrane-spanning 4-domains subfamily A member 7

2

0

High-throughput

0.316

High

644429

S39A2
Zinc transporter ZIP2

2

0

High-throughput

0.316

High

644430

SPAG4
Sperm-associated antigen 4 protein

2

0

High-throughput

0.316

High

644431

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.316

High

644432

SAR1A
Small COPII coat GTPase SAR1A

2

0

High-throughput

0.316

High

644436

SIT1
Signaling threshold-regulating transmembrane adapter 1

2

0

High-throughput

0.316

High

644416

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

0

High-throughput

0.282

High

644421

TMM79
Transmembrane protein 79

1

0

High-throughput

0.282

High

644393

AQP6
Aquaporin-6

1

0

High-throughput

0.251

Low

644389

EMP3
Epithelial membrane protein 3

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024