Protein: VKOR1
Vitamin K epoxide reductase complex subunit 1 (EC 1.17.4.4) (Vitamin K1 2,3-epoxide reductase subunit 1)

Gene: VKOR1, VKORC1
Organism: Homo sapiens
Interactions: 129
UniProt ID: Q9BQB6

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006805 - xenobiotic metabolic process
GO:0007596 - blood coagulation
GO:0010243 - response to organonitrogen compound

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1285258

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

1

High-throughput

0.606

High

216816

CREB3
Cyclic AMP-responsive element-binding protein 3

2

1

High-throughput

0.590

High

1198151

TM11B
Transmembrane protease serine 11B

2

2

High-throughput

0.558

High

1134990

GORAB
RAB6-interacting golgin

2

1

High-throughput

0.553

High

1255412

GP152
Probable G-protein coupled receptor 152

2

6

High-throughput

0.553

High

1303141

RMD3
Regulator of microtubule dynamics protein 3

2

1

High-throughput

0.553

High

1309363

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

1

Small-scale

0.552

High

714689

CNR2
Cannabinoid receptor 2

1

2

Small-scale

0.536

High

1309378

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.536

High

1068339

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

Small-scale

0.529

High

1309386

SERP1
Stress-associated endoplasmic reticulum protein 1

1

0

Small-scale

0.529

High

370312

ESR1
Estrogen receptor

2

3

High-throughput

0.521

High

1309383

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

2

High-throughput

0.515

High

1034524

OS9
Protein OS-9

1

0

High-throughput

0.513

High

1309366

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

1309385

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

1132959

CSCL2
CSC1-like protein 2

1

1

High-throughput

0.489

High

1218938

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

310775

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

Small-scale

0.481

High

434850

CXB1
Gap junction beta-1 protein

1

1

Small-scale

0.481

High

847630

BAP31
B-cell receptor-associated protein 31

1

1

Small-scale

0.481

High

1165899

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1229632

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

1

Small-scale

0.479

High

177983

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.470

High

173762

SURF4
Surfeit locus protein 4

1

0

Small-scale

0.460

High

275096

RENR
Renin receptor

1

0

Small-scale

0.460

High

277747

PRAF3
PRA1 family protein 3

1

0

Small-scale

0.460

High

296218

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

Small-scale

0.460

High

303946

YIF1A
Protein YIF1A

1

0

Small-scale

0.460

High

344233

A1AT
Alpha-1-antitrypsin

1

0

Small-scale

0.460

High

361645

APOC1
Apolipoprotein C-I

1

0

Small-scale

0.460

High

614419

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

Small-scale

0.460

High

882195

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

0

Small-scale

0.460

High

961798

REEP5
Receptor expression-enhancing protein 5

1

0

Small-scale

0.460

High

982768

PLP2
Proteolipid protein 2

1

0

Small-scale

0.460

High

1053809

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

Small-scale

0.460

High

1067807

PDIA6
Protein disulfide-isomerase A6

1

0

Small-scale

0.460

High

1075565

TRAM1
Translocating chain-associated membrane protein 1

1

0

Small-scale

0.460

High

1078816

MSMO1
Methylsterol monooxygenase 1

1

0

Small-scale

0.460

High

1166326

TMT1B
Thiol S-methyltransferase TMT1B

1

0

Small-scale

0.460

High

1234917

JAGN1
Protein jagunal homolog 1

1

0

Small-scale

0.460

High

1282564

SPTSA
Serine palmitoyltransferase small subunit A

1

0

Small-scale

0.460

High

1283559

TM230
Transmembrane protein 230

1

0

Small-scale

0.460

High

1309373

TREX1
Three-prime repair exonuclease 1

1

0

Small-scale

0.460

High

1309382

EPCR
Endothelial protein C receptor

1

0

Small-scale

0.460

High

1309384

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.460

High

341235

HPT
Haptoglobin

1

4

Small-scale

0.439

High

341264

HPTR
Haptoglobin-related protein

1

3

Small-scale

0.439

High

362027

FIBG
Fibrinogen gamma chain

1

1

Small-scale

0.439

High

426796

ASGR1
Asialoglycoprotein receptor 1

1

1

Small-scale

0.439

High

426863

ASGR2
Asialoglycoprotein receptor 2

1

1

Small-scale

0.439

High

446061

CD63
CD63 antigen

1

5

Small-scale

0.439

High

455007

C1S
Complement C1s subcomponent

1

4

Small-scale

0.439

High

602278

CD9
CD9 antigen

1

5

Small-scale

0.439

High

887941

CD81
CD81 antigen

1

6

Small-scale

0.439

High

996509

FGL1
Fibrinogen-like protein 1

1

1

Small-scale

0.439

High

1288066

RMD1
Regulator of microtubule dynamics protein 1

1

1

Small-scale

0.439

High

1302906

KCNKH
Potassium channel subfamily K member 17

1

1

Small-scale

0.439

High

204556

PROM1
Prominin-1

1

0

Small-scale

0.438

High

377643

GCR
Glucocorticoid receptor

1

3

High-throughput

0.437

High

1269469

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

1309379

HDAC6
Histone deacetylase 6

2

0

Small-scale

0.320

High

554360

MUC1
Mucin-1

2

0

High-throughput

0.316

High

1128691

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1192777

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

1252595

S7A14
Solute carrier family 7 member 14

2

0

High-throughput

0.316

High

1296507

F210B
Protein FAM210B, mitochondrial

2

0

High-throughput

0.316

High

1309370

MANBL
Protein MANBAL

2

0

High-throughput

0.316

High

157813

T4S5
Transmembrane 4 L6 family member 5

1

0

High-throughput

0.279

Low

1030859

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1033540

ILK
Integrin-linked protein kinase

1

0

High-throughput

0.279

Low

1068057

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

1309381

CDC23
Cell division cycle protein 23 homolog

1

0

High-throughput

0.279

Low

848563

CAV2
Caveolin-2

1

0

High-throughput

0.269

Low

3276

A0A0S2Z4U3
Syndecan

1

0

High-throughput

0.268

Low

1031785

BIK
Bcl-2-interacting killer

1

0

High-throughput

0.268

Low

1309371

SAR1A
Small COPII coat GTPase SAR1A

1

0

High-throughput

0.268

Low

173305

S22A2
Solute carrier family 22 member 2

1

0

Small-scale

0.251

Low

179324

COPT2
Protein SLC31A2

1

0

Small-scale

0.251

Low

360339

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

361390

APOA1
Apolipoprotein A-I

1

0

Small-scale

0.251

Low

361603

APOA2
Apolipoprotein A-II

1

0

Small-scale

0.251

Low

361706

APOC3
Apolipoprotein C-III

1

0

Small-scale

0.251

Low

363534

FETUA
Alpha-2-HS-glycoprotein

1

0

Small-scale

0.251

Low

364604

TRFE
Serotransferrin

1

0

Small-scale

0.251

Low

365040

FRIL
Ferritin light chain

1

0

Small-scale

0.251

Low

483494

SAA1
Serum amyloid A-1 protein

1

0

Small-scale

0.251

Low

600053

SAT1
Diamine acetyltransferase 1

1

0

Small-scale

0.251

Low

602575

COMT
Catechol O-methyltransferase

1

0

Small-scale

0.251

Low

603232

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

0

Small-scale

0.251

Low

786497

STAT6
Signal transducer and activator of transcription 6

1

0

Small-scale

0.251

Low

816844

AT5G3
ATP synthase F(0) complex subunit C3, mitochondrial

1

0

Small-scale

0.251

Low

836873

DNLI4
DNA ligase 4

1

0

High-throughput

0.251

Low

858316

TXTP
Tricarboxylate transport protein, mitochondrial

1

0

Small-scale

0.251

Low

874422

APOC4
Apolipoprotein C-IV

1

0

Small-scale

0.251

Low

940544

CXAR
Coxsackievirus and adenovirus receptor

1

0

Small-scale

0.251

Low

943185

CLD10
Claudin-10

1

0

Small-scale

0.251

Low

945827

MT1X
Metallothionein-1X

1

0

Small-scale

0.251

Low

946360

HEPC
Hepcidin

1

0

Small-scale

0.251

Low

965816

IFM3
Interferon-induced transmembrane protein 3

1

0

Small-scale

0.251

Low

987540

APLP2
Amyloid beta precursor like protein 2

1

0

Small-scale

0.251

Low

993904

PCDH1
Protocadherin-1

1

0

Small-scale

0.251

Low

1073407

CNN3
Calponin-3

1

0

Small-scale

0.251

Low

1222086

S15A3
Solute carrier family 15 member 3

1

0

Small-scale

0.251

Low

1231577

ZCH24
Zinc finger CCHC domain-containing protein 24

1

0

Small-scale

0.251

Low

1231814

TM256
Transmembrane protein 256

1

0

Small-scale

0.251

Low

1241890

TM35B
Transmembrane protein 35B

1

0

Small-scale

0.251

Low

1260014

CCD12
Coiled-coil domain-containing protein 12

1

0

Small-scale

0.251

Low

1284913

TM45B
Transmembrane protein 45B

1

0

Small-scale

0.251

Low

1293680

T176A
Transmembrane protein 176A

1

0

Small-scale

0.251

Low

1309364

TACAN
Ion channel TACAN

1

0

Small-scale

0.251

Low

1309365

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

1

0

Small-scale

0.251

Low

1309367

TM134
Transmembrane protein 134

1

0

Small-scale

0.251

Low

1309368

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

0

Small-scale

0.251

Low

1309369

LFG4
Protein lifeguard 4

1

0

Small-scale

0.251

Low

1309372

HOME2
Homer protein homolog 2

1

0

Small-scale

0.251

Low

1309374

ECHD1
Ethylmalonyl-CoA decarboxylase

1

0

Small-scale

0.251

Low

1309375

TM242
Transmembrane protein 242

1

0

Small-scale

0.251

Low

1309376

MSRB1
Methionine-R-sulfoxide reductase B1

1

0

Small-scale

0.251

Low

1309377

CC167
Coiled-coil domain-containing protein 167

1

0

Small-scale

0.251

Low

214358

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

824318

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

917824

H4
Histone H4

1

0

High-throughput

0.249

Low

1043544

CUL4B
Cullin-4B

1

0

High-throughput

0.249

Low

1222690

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

1309380

UBQL2
Ubiquilin-2

1

0

High-throughput

0.249

Low

1087818

MEP1B
Meprin A subunit beta

1

0

Small-scale

0.238

Low

209281

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024