Protein: GIT2
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)

Gene: GIT2
Organism: Homo sapiens
Interactions: 133
UniProt ID: Q14161

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005654 - nucleoplasm
GO:0005925 - focal adhesion
GO:0007420 - brain development
GO:0008277 - regulation of G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1049704

ARHG7
Rho guanine nucleotide exchange factor 7

6

20

Small-scale

0.950

High

1050107

ARHG6
Rho guanine nucleotide exchange factor 6

6

20

High-throughput

0.946

High

823392

PAXI
Paxillin

6

20

Small-scale

0.935

High

1026160

PAK1
Serine/threonine-protein kinase PAK 1

5

13

Small-scale

0.916

High

1050177

GIT1
ARF GTPase-activating protein GIT1

4

14

Small-scale

0.907

High

1026906

PAK2
Serine/threonine-protein kinase PAK 2

3

12

High-throughput

0.855

High

238962

LPXN
Leupaxin

2

20

High-throughput

0.811

High

1050113

KCC4
Calcium/calmodulin-dependent protein kinase type IV

2

11

High-throughput

0.811

High

209052

NCK2
Cytoplasmic protein NCK2

3

20

High-throughput

0.770

High

894000

CDC42
Cell division control protein 42 homolog

2

20

High-throughput

0.768

High

1050178

NEMO
NF-kappa-B essential modulator

1

16

High-throughput

0.764

High

557688

NCK1
SH2/SH3 adapter protein NCK1

3

20

High-throughput

0.751

High

1050166

SPN90
NCK-interacting protein with SH3 domain

2

2

High-throughput

0.726

High

586744

CSK22
Casein kinase II subunit alpha'

1

5

High-throughput

0.691

High

1050176

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

15

High-throughput

0.691

High

863096

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

1

High-throughput

0.667

High

1050173

MAFF
Transcription factor MafF

3

2

High-throughput

0.667

High

400070

ICAM1
Intercellular adhesion molecule 1

2

9

High-throughput

0.628

High

719803

RECO
Recoverin

1

1

High-throughput

0.625

High

1050112

IKBB
NF-kappa-B inhibitor beta

1

18

High-throughput

0.625

High

1050103

GIT2
ARF GTPase-activating protein GIT2

1

15

Small-scale

0.621

High

1050161

SHLB2
Endophilin-B2

1

16

High-throughput

0.621

High

545371

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

626649

ARBK1
Beta-adrenergic receptor kinase 1

1

9

Small-scale

0.618

High

925274

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

950990

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1050123

PKN3
Serine/threonine-protein kinase N3

1

12

High-throughput

0.618

High

1050126

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1050143

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

904553

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

982004

1433F
14-3-3 protein eta

2

20

High-throughput

0.601

High

1050106

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.582

High

1050128

GET4
Golgi to ER traffic protein 4 homolog

2

0

High-throughput

0.580

High

1050154

SYNCI
Syncoilin

2

7

High-throughput

0.574

High

1050162

EXOC1
Exocyst complex component 1

2

3

High-throughput

0.574

High

1050163

FBX28
F-box only protein 28

2

1

High-throughput

0.574

High

1050167

TMOD4
Tropomodulin-4

2

8

High-throughput

0.574

High

307174

KLHL2
Kelch-like protein 2

2

4

High-throughput

0.558

High

1050111

TSN
Translin

1

0

High-throughput

0.558

High

1050160

MED4
Mediator of RNA polymerase II transcription subunit 4

1

4

High-throughput

0.554

High

120434

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.553

High

564527

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.553

High

892368

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.553

High

1050119

PHLB3
Pleckstrin homology-like domain family B member 3

1

8

High-throughput

0.553

High

1050125

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.553

High

1050152

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

1050153

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

1050156

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.553

High

214265

SPOP
Speckle-type POZ protein

1

4

High-throughput

0.541

High

595220

LMNB1
Lamin-B1

1

7

High-throughput

0.541

High

950179

SMAD3
Mothers against decapentaplegic homolog 3

1

7

High-throughput

0.541

High

1050104

E2F2
Transcription factor E2F2

1

6

High-throughput

0.541

High

1050174

UBQL1
Ubiquilin-1

1

3

High-throughput

0.541

High

199189

ZNHI1
Zinc finger HIT domain-containing protein 1

1

1

High-throughput

0.536

High

928908

SKP1
S-phase kinase-associated protein 1

1

1

High-throughput

0.536

High

1049946

SCRIB
Protein scribble homolog

1

14

High-throughput

0.536

High

1050110

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

20

High-throughput

0.536

High

1050127

CENPQ
Centromere protein Q

1

1

High-throughput

0.536

High

1023658

TRAF1
TNF receptor-associated factor 1

1

2

High-throughput

0.523

High

675831

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.518

High

1050136

PROX1
Prospero homeobox protein 1

1

0

High-throughput

0.518

High

1050137

HGD
Homogentisate 1,2-dioxygenase

1

0

High-throughput

0.518

High

1050155

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

0

High-throughput

0.518

High

206365

LTOR5
Ragulator complex protein LAMTOR5

1

1

High-throughput

0.494

High

1050165

KCTD5
BTB/POZ domain-containing protein KCTD5

1

8

High-throughput

0.494

High

158100

TX1B3
Tax1-binding protein 3

1

20

High-throughput

0.489

High

245974

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.489

High

1050124

TM154
Transmembrane protein 154

1

1

High-throughput

0.489

High

1050148

KXDL1
KxDL motif-containing protein 1

1

1

High-throughput

0.489

High

1050151

UBXN6
UBX domain-containing protein 6

1

4

High-throughput

0.489

High

521541

ACTN1
Alpha-actinin-1

1

20

High-throughput

0.481

High

607652

NDKB
Nucleoside diphosphate kinase B

1

1

High-throughput

0.481

High

929860

ACTG
Actin, cytoplasmic 2

1

15

High-throughput

0.481

High

1025377

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

19

High-throughput

0.481

High

1049454

SAFB2
Scaffold attachment factor B2

1

6

High-throughput

0.481

High

1050121

EDC4
Enhancer of mRNA-decapping protein 4

1

6

High-throughput

0.481

High

1050147

RUFY1
RUN and FYVE domain-containing protein 1

1

8

High-throughput

0.481

High

1050149

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

3

High-throughput

0.481

High

1050175

ATF5
Cyclic AMP-dependent transcription factor ATF-5

1

3

High-throughput

0.481

High

1050179

PCLO
Protein piccolo

1

15

Small-scale

0.481

High

122190

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

1

High-throughput

0.479

High

126129

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

4

High-throughput

0.479

High

181520

CLOCK
Circadian locomoter output cycles protein kaput

1

4

High-throughput

0.479

High

409069

K2C8
Keratin, type II cytoskeletal 8

1

2

High-throughput

0.479

High

430176

PROF1
Profilin-1

1

4

High-throughput

0.479

High

471584

TFPT
TCF3 fusion partner

1

1

High-throughput

0.479

High

898118

MAX
Protein max

1

10

High-throughput

0.479

High

1050109

RABE1
Rab GTPase-binding effector protein 1

1

11

High-throughput

0.479

High

1050114

GRAP1
GRIP1-associated protein 1

1

10

High-throughput

0.479

High

1050130

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

11

High-throughput

0.479

High

1050133

GOGA5
Golgin subfamily A member 5

1

13

High-throughput

0.479

High

1050135

HDAC2
Histone deacetylase 2

1

10

High-throughput

0.479

High

1050138

FBXW7
F-box/WD repeat-containing protein 7

1

10

High-throughput

0.479

High

1050140

PF21A
PHD finger protein 21A

1

9

High-throughput

0.479

High

1050145

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

2

High-throughput

0.479

High

1050150

NUF2
Kinetochore protein Nuf2

1

16

High-throughput

0.479

High

1050168

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

1050171

RABX5
Rab5 GDP/GTP exchange factor

1

1

High-throughput

0.479

High

1050172

RCOR1
REST corepressor 1

1

6

High-throughput

0.479

High

1050131

RUSC2
AP-4 complex accessory subunit RUSC2

1

0

High-throughput

0.460

High

204322

MS18B
Protein Mis18-beta

1

0

High-throughput

0.458

High

317436

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.458

High

1050120

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.458

High

1050141

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.458

High

1050146

CK5P2
CDK5 regulatory subunit-associated protein 2

1

17

High-throughput

0.445

High

372955

C4BPA
C4b-binding protein alpha chain

1

2

High-throughput

0.439

High

408798

K1C18
Keratin, type I cytoskeletal 18

1

4

High-throughput

0.439

High

599665

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

14

High-throughput

0.439

High

678272

COR1A
Coronin-1A

1

12

High-throughput

0.439

High

1050108

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

2

High-throughput

0.439

High

1050132

USBP1
Harmonin-binding protein USHBP1

1

10

High-throughput

0.439

High

81711

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

1

High-throughput

0.437

High

322614

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

13

High-throughput

0.437

High

1050115

EIPR1
EARP and GARP complex-interacting protein 1

1

5

High-throughput

0.437

High

1050116

CCD93
Coiled-coil domain-containing protein 93

1

7

High-throughput

0.437

High

1050118

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.437

High

1050122

FBX42
F-box only protein 42

1

5

High-throughput

0.437

High

1050129

HAUS6
HAUS augmin-like complex subunit 6

1

1

High-throughput

0.437

High

1050134

CCHCR
Coiled-coil alpha-helical rod protein 1

1

11

High-throughput

0.437

High

1050139

VP33A
Vacuolar protein sorting-associated protein 33A

1

4

High-throughput

0.437

High

1050144

SNX27
Sorting nexin-27

1

20

High-throughput

0.437

High

1050157

NCK5L
Nck-associated protein 5-like

1

3

High-throughput

0.437

High

1050158

TUFT1
Tuftelin

1

3

High-throughput

0.437

High

1050159

HM20A
High mobility group protein 20A

1

5

High-throughput

0.437

High

1050170

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

1

High-throughput

0.437

High

89964

D6R9G5
Kelch like family member 2

1

6

High-throughput

0.407

High

437676

BGLR
Beta-glucuronidase

1

0

High-throughput

0.282

High

1050164

FGOP2
FGFR1 oncogene partner 2

1

0

High-throughput

0.279

Low

1050105

MVP
Major vault protein

1

0

High-throughput

0.251

Low

1050117

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

0

High-throughput

0.249

Low

1050142

VPS50
Syndetin

1

0

High-throughput

0.249

Low

1050169

OPN4
Melanopsin

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024