Protein: HMGX4
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)

Gene: HMGX4, HMGXB4
Organism: Homo sapiens
Interactions: 114
UniProt ID: Q9UGU5

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0008333 - endosome to lysosome transport
GO:0016055 - Wnt signaling pathway
GO:0016589 - NURF complex
GO:0030178 - negative regulation of Wnt signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1355192

HMGX4
HMG domain-containing protein 4

2

20

High-throughput

0.783

High

996946

SSRP1
FACT complex subunit SSRP1

1

19

High-throughput

0.691

High

1221084

BAP18
Chromatin complexes subunit BAP18

4

0

High-throughput

0.657

High

997946

RBBP4
Histone-binding protein RBBP4

2

20

High-throughput

0.628

High

853746

IMA5
Importin subunit alpha-5

1

9

High-throughput

0.618

High

229516

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

2

20

High-throughput

0.611

High

658748

SMCA1
Probable global transcription activator SNF2L1

2

20

High-throughput

0.611

High

278345

PIAS2
E3 SUMO-protein ligase PIAS2

2

8

High-throughput

0.606

High

1302239

STRBP
Spermatid perinuclear RNA-binding protein

2

20

High-throughput

0.606

High

918757

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.584

High

935342

H31
Histone H3.1

2

20

High-throughput

0.584

High

470196

H2AZ
Histone H2A.Z

2

20

High-throughput

0.558

High

968730

AK17A
A-kinase anchor protein 17A

2

4

High-throughput

0.553

High

1297827

STAC3
SH3 and cysteine-rich domain-containing protein 3

2

4

High-throughput

0.553

High

1299873

LENG8
Leukocyte receptor cluster member 8

2

11

High-throughput

0.553

High

1329381

TSYL2
Testis-specific Y-encoded-like protein 2

2

6

High-throughput

0.553

High

1067176

BRD3
Bromodomain-containing protein 3

2

20

High-throughput

0.549

High

669048

PML
Protein PML

1

20

High-throughput

0.536

High

1059573

KIF22
Kinesin-like protein KIF22

1

2

High-throughput

0.536

High

1087463

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

370641

ESR1
Estrogen receptor

2

20

High-throughput

0.521

High

874399

NR1H2
Oxysterols receptor LXR-beta

1

14

High-throughput

0.508

High

236118

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

High-throughput

0.489

High

488097

RRAS
Ras-related protein R-Ras

1

5

High-throughput

0.489

High

795798

MAGA3
Melanoma-associated antigen 3

1

5

High-throughput

0.489

High

964277

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.489

High

1158592

L2GL2
LLGL scribble cell polarity complex component 2

1

7

High-throughput

0.489

High

1159488

DJC24
DnaJ homolog subfamily C member 24

1

6

High-throughput

0.489

High

1230193

CNTRB
Centrobin

1

4

High-throughput

0.489

High

1271815

KIFA3
Kinesin-associated protein 3

1

20

High-throughput

0.489

High

1299069

ARAP1
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

1

11

High-throughput

0.489

High

198070

PHF1
PHD finger protein 1

1

4

High-throughput

0.479

High

265276

SAP30
Histone deacetylase complex subunit SAP30

1

2

High-throughput

0.479

High

328672

MBD3
Methyl-CpG-binding domain protein 3

1

8

High-throughput

0.479

High

379986

MYCN
N-myc proto-oncogene protein

1

18

High-throughput

0.479

High

632942

TYY1
Transcriptional repressor protein YY1

1

13

High-throughput

0.479

High

828414

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

918089

H4
Histone H4

1

12

High-throughput

0.479

High

1017364

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

1018734

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.479

High

1059923

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.479

High

1061793

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

20

High-throughput

0.479

High

1117713

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

1137057

LIN9
Protein lin-9 homolog

1

2

High-throughput

0.479

High

1241374

HJURP
Holliday junction recognition protein

1

1

High-throughput

0.479

High

1255050

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

20

High-throughput

0.479

High

1302469

SIN3A
Paired amphipathic helix protein Sin3a

1

8

High-throughput

0.479

High

1350618

ZN219
Zinc finger protein 219

1

9

High-throughput

0.479

High

1353858

MBD2
Methyl-CpG-binding domain protein 2

1

8

High-throughput

0.479

High

1354745

ZRAN1
Ubiquitin thioesterase ZRANB1

1

15

High-throughput

0.479

High

1355194

MTF2
Metal-response element-binding transcription factor 2

1

4

High-throughput

0.479

High

538439

ENPL
Endoplasmin

1

8

High-throughput

0.470

High

1183315

Q7KZS0
SUMO-conjugating enzyme UBC9

1

11

High-throughput

0.470

High

1254524

CCHCR
Coiled-coil alpha-helical rod protein 1

1

4

High-throughput

0.470

High

1327844

ENKD1
Enkurin domain-containing protein 1

1

1

High-throughput

0.470

High

1077356

T22D1
TSC22 domain family protein 1

1

20

High-throughput

0.464

High

1157397

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

7

High-throughput

0.464

High

310415

EPM2A
Laforin

1

0

Small-scale

0.460

High

902791

SUMO2
Small ubiquitin-related modifier 2

1

15

High-throughput

0.457

High

943007

SRPK2
SRSF protein kinase 2

1

12

High-throughput

0.457

High

1318617

DPY30
Protein dpy-30 homolog

1

1

Small-scale

0.457

High

594272

MX1
Interferon-induced GTP-binding protein Mx1

1

5

Small-scale

0.439

High

930436

UBC9
SUMO-conjugating enzyme UBC9

1

11

High-throughput

0.439

High

1128557

HABP4
Intracellular hyaluronan-binding protein 4

1

3

Small-scale

0.439

High

1270819

CBP
CREB-binding protein

1

20

Small-scale

0.439

High

245060

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.437

High

257845

SIN3B
Paired amphipathic helix protein Sin3b

1

8

High-throughput

0.437

High

260047

TBCA
Tubulin-specific chaperone A

1

1

High-throughput

0.437

High

268320

EED
Polycomb protein EED

1

20

High-throughput

0.437

High

296166

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.437

High

304380

UBR5
E3 ubiquitin-protein ligase UBR5

1

14

High-throughput

0.437

High

486978

MYBB
Myb-related protein B

1

4

High-throughput

0.437

High

631620

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.437

High

952681

H33
Histone H3.3

1

20

High-throughput

0.437

High

1024531

CAF1A
Chromatin assembly factor 1 subunit A

1

8

High-throughput

0.437

High

1024605

CAF1B
Chromatin assembly factor 1 subunit B

1

20

High-throughput

0.437

High

1027314

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.437

High

1031968

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.437

High

1063665

SUZ12
Polycomb protein SUZ12

1

2

High-throughput

0.437

High

1080447

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.437

High

1129665

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

8

High-throughput

0.437

High

1163896

RICTR
Rapamycin-insensitive companion of mTOR

1

3

High-throughput

0.437

High

1205831

P66A
Transcriptional repressor p66-alpha

1

12

High-throughput

0.437

High

1221806

SMC5
Structural maintenance of chromosomes protein 5

1

12

High-throughput

0.437

High

1260519

ZN296
Zinc finger protein 296

1

9

High-throughput

0.437

High

1263990

P66B
Transcriptional repressor p66-beta

1

12

High-throughput

0.437

High

1270725

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.437

High

1296263

Z512B
Zinc finger protein 512B

1

9

High-throughput

0.437

High

1298463

PWP2A
PWWP domain-containing protein 2A

1

6

High-throughput

0.437

High

1300621

PHF12
PHD finger protein 12

1

20

High-throughput

0.437

High

1312039

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.437

High

1327634

SP130
Histone deacetylase complex subunit SAP130

1

17

High-throughput

0.437

High

1328479

BC11A
B-cell lymphoma/leukemia 11A

1

8

High-throughput

0.437

High

1333166

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

8

High-throughput

0.437

High

1348368

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

5

High-throughput

0.437

High

1355193

ZN330
Zinc finger protein 330

1

4

High-throughput

0.437

High

1086344

H31T
Histone H3.1t

1

20

High-throughput

0.408

High

91369

E5RIW3
Tubulin-specific chaperone A

1

1

High-throughput

0.407

High

1172907

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.316

High

1252901

ZCH10
Zinc finger CCHC domain-containing protein 10

2

0

High-throughput

0.316

High

1283003

TET5B
Terminal nucleotidyltransferase 5B

2

0

High-throughput

0.316

High

1318205

UBL5
Ubiquitin-like protein 5

2

0

High-throughput

0.316

High

1318763

IN80B
INO80 complex subunit B

2

0

High-throughput

0.316

High

988156

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.279

Low

410639

DCUP
Uroporphyrinogen decarboxylase

1

0

High-throughput

0.265

Low

533634

TNNT1
Troponin T, slow skeletal muscle

1

0

High-throughput

0.265

Low

81769

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.249

Low

146879

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.249

Low

158868

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.249

Low

1119832

LIN52
Protein lin-52 homolog

1

0

High-throughput

0.249

Low

1260559

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.249

Low

1292975

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.249

Low

1129944

RBG1L
Rab GTPase-activating protein 1-like

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024