Protein: KI2L4
Killer cell immunoglobulin-like receptor 2DL4 (CD158 antigen-like family member D) (G9P) (Killer cell inhibitory receptor 103AS) (KIR-103AS) (MHC class I NK cell receptor KIR103AS) (CD antigen CD158d)

Gene: KI2L4, KIR2DL4
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q99706

Gene Ontology (top 5):
GO:0002729 - positive regulation of natural killer cell cytokine production
GO:0004888 - transmembrane signaling receptor activity
GO:0005886 - plasma membrane
GO:0006968 - cellular defense response
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

570369

HLAG
HLA class I histocompatibility antigen, alpha chain G

2

20

Small-scale

0.768

High

1147816

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

20

High-throughput

0.691

High

442917

FCG3A
Low affinity immunoglobulin gamma Fc region receptor III-A

1

11

Small-scale

0.618

High

672990

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

2

5

Small-scale

0.584

High

1076516

TRIP6
Thyroid receptor-interacting protein 6

1

5

High-throughput

0.573

High

1136604

FHL5
Four and a half LIM domains protein 5

2

4

High-throughput

0.553

High

1305748

BPIA1
BPI fold-containing family A member 1

2

1

High-throughput

0.553

High

154408

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

7

High-throughput

0.536

High

160165

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

18

High-throughput

0.536

High

178257

IPO8
Importin-8

1

4

High-throughput

0.536

High

209351

TSN6
Tetraspanin-6

1

7

High-throughput

0.536

High

312372

IPO7
Importin-7

1

5

High-throughput

0.536

High

530957

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

555186

CD44
CD44 antigen

1

3

High-throughput

0.536

High

619278

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

9

High-throughput

0.536

High

871954

AT12A
Potassium-transporting ATPase alpha chain 2

1

1

High-throughput

0.536

High

944389

PRKDC
DNA-dependent protein kinase catalytic subunit

1

2

High-throughput

0.536

High

966869

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

8

High-throughput

0.536

High

971056

DSC2
Desmocollin-2

1

9

High-throughput

0.536

High

1066579

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.536

High

1079414

VAMP3
Vesicle-associated membrane protein 3

1

5

High-throughput

0.536

High

1125109

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.536

High

1146075

TBC9B
TBC1 domain family member 9B

1

5

High-throughput

0.536

High

1162110

RHDF2
Inactive rhomboid protein 2

1

3

High-throughput

0.536

High

1168252

CERS6
Ceramide synthase 6

1

1

High-throughput

0.536

High

1201484

LAP4B
Lysosomal-associated transmembrane protein 4B

1

2

High-throughput

0.536

High

1250925

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

1

High-throughput

0.536

High

1253532

CIP2A
Protein CIP2A

1

1

High-throughput

0.536

High

1267663

SL9A6
Sodium/hydrogen exchanger 6

1

1

High-throughput

0.536

High

1282925

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

2

High-throughput

0.536

High

1301929

MYADM
Myeloid-associated differentiation marker

1

3

High-throughput

0.536

High

1305741

PKP2
Plakophilin-2

1

6

High-throughput

0.536

High

1305747

AT131
Endoplasmic reticulum transmembrane helix translocase

1

3

High-throughput

0.536

High

1305751

GINM1
Glycoprotein integral membrane protein 1

1

1

High-throughput

0.536

High

1305756

LRP12
Low-density lipoprotein receptor-related protein 12

1

2

High-throughput

0.536

High

1305758

MTCH2
Mitochondrial carrier homolog 2

1

3

High-throughput

0.536

High

168443

SCAM1
Secretory carrier-associated membrane protein 1

1

0

High-throughput

0.513

High

199380

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.513

High

240908

S19A2
Thiamine transporter 1

1

0

High-throughput

0.513

High

351097

LDLR
Low-density lipoprotein receptor

1

0

High-throughput

0.513

High

546670

B4GT1
Beta-1,4-galactosyltransferase 1

1

0

High-throughput

0.513

High

702286

CD70
CD70 antigen

1

0

High-throughput

0.513

High

741162

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

1

0

High-throughput

0.513

High

1220573

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.513

High

1232562

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.513

High

1253934

SPP2A
Signal peptide peptidase-like 2A

1

0

High-throughput

0.513

High

1260047

CHPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.513

High

1261722

CANT1
Soluble calcium-activated nucleotidase 1

1

0

High-throughput

0.513

High

1291352

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.513

High

1293089

S39AD
Zinc transporter ZIP13

1

0

High-throughput

0.513

High

1296324

EXOC2
Exocyst complex component 2

1

0

High-throughput

0.513

High

1300635

XPO6
Exportin-6

1

0

High-throughput

0.513

High

1305742

G6PC3
Glucose-6-phosphatase 3

1

0

High-throughput

0.513

High

1305744

YIPF3
Protein YIPF3

1

0

High-throughput

0.513

High

1305745

INT2
Integrator complex subunit 2

1

0

High-throughput

0.513

High

1305746

F234A
Protein FAM234A

1

0

High-throughput

0.513

High

155629

TNPO2
Transportin-2

1

5

High-throughput

0.489

High

207986

XPOT
Exportin-T

1

7

High-throughput

0.489

High

235207

STX10
Syntaxin-10

1

4

High-throughput

0.489

High

279338

DNJB5
DnaJ homolog subfamily B member 5

1

3

High-throughput

0.489

High

296967

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.489

High

301229

RHBT3
Rho-related BTB domain-containing protein 3

1

8

High-throughput

0.489

High

885602

MLF1
Myeloid leukemia factor 1

1

1

High-throughput

0.489

High

986023

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

High-throughput

0.489

High

1121754

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

3

High-throughput

0.489

High

1155873

PHLB3
Pleckstrin homology-like domain family B member 3

1

3

High-throughput

0.489

High

1157270

ZNT6
Zinc transporter 6

1

1

High-throughput

0.489

High

1165076

MOXD1
DBH-like monooxygenase protein 1

1

1

High-throughput

0.489

High

1170414

TBCD9
TBC1 domain family member 9

1

6

High-throughput

0.489

High

1266284

FAM3C
Protein FAM3C

1

2

High-throughput

0.489

High

1273388

GLMN
Glomulin

1

2

High-throughput

0.489

High

1301643

JMJD8
JmjC domain-containing protein 8

1

1

High-throughput

0.489

High

1305743

XPO4
Exportin-4

1

3

High-throughput

0.489

High

1305754

TMED7
Transmembrane emp24 domain-containing protein 7

1

1

High-throughput

0.489

High

1305757

TNPO3
Transportin-3

1

9

High-throughput

0.489

High

1305755

TRAF6
TNF receptor-associated factor 6

1

5

Small-scale

0.479

High

435163

SP1
Transcription factor Sp1

1

2

Small-scale

0.437

High

474532

GPHRB
Golgi pH regulator B

1

1

High-throughput

0.437

High

542069

ETS1
Protein C-ets-1

1

2

Small-scale

0.437

High

575556

EGR1
Early growth response protein 1

1

3

High-throughput

0.437

High

964411

RUNX1
Runt-related transcription factor 1

1

3

Small-scale

0.437

High

1045139

RUNX3
Runt-related transcription factor 3

1

3

Small-scale

0.437

High

81837

GPHRA
Golgi pH regulator A

1

1

High-throughput

0.407

High

1012319

INCA1
Protein INCA1

2

0

High-throughput

0.316

High

1305749

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.316

High

1305752

RN216
E3 ubiquitin-protein ligase RNF216

1

0

Small-scale

0.299

High

1274207

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.299

High

238008

EXOC3
Exocyst complex component 3

1

0

High-throughput

0.279

Low

303944

YIF1A
Protein YIF1A

1

0

High-throughput

0.279

Low

381027

SEMG1
Semenogelin-1

1

0

High-throughput

0.279

Low

1148326

INT3
Integrator complex subunit 3

1

0

High-throughput

0.279

Low

1156498

RINT1
RAD50-interacting protein 1

1

0

High-throughput

0.279

Low

1188051

SETX
Probable helicase senataxin

1

0

High-throughput

0.279

Low

1232467

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

0

High-throughput

0.279

Low

1263162

NELFB
Negative elongation factor B

1

0

High-throughput

0.279

Low

1290263

MITOK
Mitochondrial potassium channel

1

0

High-throughput

0.279

Low

1293885

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

1305750

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.279

Low

1305753

DOLK
Dolichol kinase

1

0

High-throughput

0.279

Low

478746

PNM6A
Paraneoplastic antigen-like protein 6A

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024