Protein: AF17
Protein AF-17 (ALL1-fused gene from chromosome 17 protein)

Gene: AF17, MLLT6
Organism: Homo sapiens
Interactions: 92
UniProt ID: P55198

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006325 - chromatin organization
GO:0006355 - regulation of DNA-templated transcription
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0010765 - positive regulation of sodium ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

876556

AF10
Protein AF-10

3

14

Small-scale

0.871

High

876611

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

5

3

Small-scale

0.728

High

876591

CREB5
Cyclic AMP-responsive element-binding protein 5

4

6

High-throughput

0.698

High

862899

CEBPG
CCAAT/enhancer-binding protein gamma

3

10

High-throughput

0.678

High

788018

AF9
Protein AF-9

3

7

Small-scale

0.675

High

401708

JUN
Transcription factor Jun

2

9

High-throughput

0.628

High

547760

ATF2
Cyclic AMP-dependent transcription factor ATF-2

2

5

High-throughput

0.628

High

568081

JUND
Transcription factor JunD

2

5

High-throughput

0.628

High

568255

ATF7
Cyclic AMP-dependent transcription factor ATF-7

2

5

High-throughput

0.628

High

669320

EF1D
Elongation factor 1-delta

2

4

High-throughput

0.628

High

876595

TLE5
TLE family member 5

2

3

High-throughput

0.606

High

829221

SYCC
Cysteine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.602

High

876615

ZC3HA
Zinc finger CCCH domain-containing protein 10

2

0

High-throughput

0.602

High

876623

UBQL4
Ubiquilin-4

1

3

High-throughput

0.582

High

876597

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

0

High-throughput

0.580

High

876614

ZMY19
Zinc finger MYND domain-containing protein 19

2

0

High-throughput

0.580

High

152770

RGPD8
RANBP2-like and GRIP domain-containing protein 8

2

5

High-throughput

0.574

High

175655

TRI18
E3 ubiquitin-protein ligase Midline-1

2

6

High-throughput

0.574

High

422369

NFM
Neurofilament medium polypeptide

2

3

High-throughput

0.574

High

623095

EF1B
Elongation factor 1-beta

2

4

High-throughput

0.574

High

643829

SYVC
Valine--tRNA ligase

2

1

High-throughput

0.574

High

876594

EF1A2
Elongation factor 1-alpha 2

2

2

High-throughput

0.574

High

876599

EEA1
Early endosome antigen 1

2

5

High-throughput

0.574

High

876607

GCC2
GRIP and coiled-coil domain-containing protein 2

2

6

High-throughput

0.574

High

876592

ENL
Protein ENL

2

10

Small-scale

0.558

High

876603

GRAP1
GRIP1-associated protein 1

2

2

High-throughput

0.553

High

159180

CSKP
Peripheral plasma membrane protein CASK

1

1

High-throughput

0.541

High

876616

MED15
Mediator of RNA polymerase II transcription subunit 15

1

3

High-throughput

0.541

High

317422

YETS4
YEATS domain-containing protein 4

1

7

High-throughput

0.536

High

596260

FILA
Filaggrin

1

3

High-throughput

0.536

High

643981

EF1G
Elongation factor 1-gamma

1

1

High-throughput

0.536

High

649390

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.536

High

751553

GRP75
Stress-70 protein, mitochondrial

1

2

High-throughput

0.536

High

795941

MAGA8
Melanoma-associated antigen 8

1

3

High-throughput

0.536

High

876588

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.536

High

876598

CUL3
Cullin-3

1

1

High-throughput

0.536

High

876626

DAXX
Death domain-associated protein 6

1

2

High-throughput

0.536

High

876601

CEBPE
CCAAT/enhancer-binding protein epsilon

1

7

Small-scale

0.527

High

876628

UBQL1
Ubiquilin-1

1

2

High-throughput

0.523

High

876585

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.515

High

81915

B7ZLY0
PHC2 protein

1

7

High-throughput

0.515

High

394411

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

876632

NEMO
NF-kappa-B essential modulator

1

5

High-throughput

0.501

High

876587

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

1

High-throughput

0.494

High

133398

NOP56
Nucleolar protein 56

1

1

High-throughput

0.489

High

876618

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

4

High-throughput

0.489

High

876631

TACC3
Transforming acidic coiled-coil-containing protein 3

1

1

High-throughput

0.489

High

171518

ZBT22
Zinc finger and BTB domain-containing protein 22

1

5

High-throughput

0.481

High

197685

CRX
Cone-rod homeobox protein

1

2

High-throughput

0.481

High

208114

SPY2
Protein sprouty homolog 2

1

2

High-throughput

0.481

High

551101

ITF2
Transcription factor 4

1

7

High-throughput

0.481

High

837884

MEOX2
Homeobox protein MOX-2

1

7

High-throughput

0.481

High

876608

PHC2
Polyhomeotic-like protein 2

1

6

High-throughput

0.481

High

876617

HTF4
Transcription factor 12

1

7

High-throughput

0.481

High

876619

NSD3
Histone-lysine N-methyltransferase NSD3

1

10

High-throughput

0.481

High

455266

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

552344

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

641354

PAX6
Paired box protein Pax-6

1

1

High-throughput

0.479

High

727494

HNF1B
Hepatocyte nuclear factor 1-beta

1

4

High-throughput

0.479

High

740485

PPARG
Peroxisome proliferator-activated receptor gamma

1

15

High-throughput

0.479

High

750197

COIL
Coilin

1

3

High-throughput

0.479

High

828180

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

831146

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.479

High

876589

H31
Histone H3.1

1

20

High-throughput

0.479

High

876590

H33
Histone H3.3

1

20

High-throughput

0.479

High

876593

TLE3
Transducin-like enhancer protein 3

1

9

High-throughput

0.479

High

876600

TRIP4
Activating signal cointegrator 1

1

1

High-throughput

0.479

High

876609

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

876612

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

876613

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

5

High-throughput

0.479

High

876620

FOXQ1
Forkhead box protein Q1

1

1

High-throughput

0.479

High

876627

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

876629

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

876630

ZN330
Zinc finger protein 330

1

3

High-throughput

0.479

High

486764

MYB
Transcriptional activator Myb

1

0

High-throughput

0.458

High

620470

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

0

High-throughput

0.458

High

787880

EPS15
Epidermal growth factor receptor substrate 15

1

3

High-throughput

0.457

High

876586

KR108
Keratin-associated protein 10-8

1

2

High-throughput

0.439

High

876602

ENOX2
Ecto-NOX disulfide-thiol exchanger 2

1

1

High-throughput

0.439

High

876621

CEP44
Centrosomal protein of 44 kDa

1

1

High-throughput

0.439

High

720077

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

876336

AFAD
Afadin

1

7

High-throughput

0.437

High

876596

GOGA2
Golgin subfamily A member 2

1

3

High-throughput

0.437

High

876610

NUP43
Nucleoporin Nup43

1

8

High-throughput

0.437

High

876604

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

876605

SGO1
Shugoshin 1

2

0

High-throughput

0.328

High

876606

IQEC1
IQ motif and SEC7 domain-containing protein 1

2

0

High-throughput

0.328

High

876625

GULP1
PTB domain-containing engulfment adapter protein 1

2

0

High-throughput

0.328

High

876624

ATX10
Ataxin-10

1

0

High-throughput

0.268

Low

100633

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

444340

K1C19
Keratin, type I cytoskeletal 19

1

0

High-throughput

0.249

Low

876622

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024