Protein: HM20A
High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1)

Gene: HM20A, HMG20A
Organism: Homo sapiens
Interactions: 230
UniProt ID: Q9NP66

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006325 - chromatin organization
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1342340

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

7

20

Small-scale

0.969

High

1342331

HM20A
High mobility group protein 20A

6

18

Small-scale

0.951

High

1270459

HDAC2
Histone deacetylase 2

7

20

Small-scale

0.752

High

232530

KDM1A
Lysine-specific histone demethylase 1A

7

20

Small-scale

0.748

High

1038736

HDAC1
Histone deacetylase 1

6

20

High-throughput

0.741

High

853482

IMA1
Importin subunit alpha-1

1

10

High-throughput

0.740

High

246496

DTNB
Dystrobrevin beta

5

2

Small-scale

0.728

High

1285365

PF21A
PHD finger protein 21A

5

20

Small-scale

0.720

High

1342351

RCOR1
REST corepressor 1

5

20

Small-scale

0.718

High

942123

RPP30
Ribonuclease P protein subunit p30

4

1

High-throughput

0.698

High

299082

PHF14
PHD finger protein 14

4

7

High-throughput

0.694

High

326782

SNAI1
Zinc finger protein SNAI1

4

10

Small-scale

0.694

High

1314677

SCNM1
Sodium channel modifier 1

4

0

High-throughput

0.668

High

1283685

MGN2
Protein mago nashi homolog 2

3

3

High-throughput

0.667

High

1282968

H2B1A
Histone H2B type 1-A

3

20

High-throughput

0.667

High

1294778

PAWR
PRKC apoptosis WT1 regulator protein

3

0

High-throughput

0.646

High

399158

FGF1
Fibroblast growth factor 1

3

0

High-throughput

0.638

High

470171

H2AZ
Histone H2A.Z

2

20

High-throughput

0.628

High

551285

ITF2
Transcription factor 4

2

6

High-throughput

0.628

High

1342346

SMBT1
Scm-like with four MBT domains protein 1

2

6

High-throughput

0.628

High

225791

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.618

High

727808

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.618

High

727930

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.618

High

818487

SOX2
Transcription factor SOX-2

1

19

High-throughput

0.618

High

881829

SOX10
Transcription factor SOX-10

1

18

High-throughput

0.618

High

1057859

GSE1
Genetic suppressor element 1

3

2

High-throughput

0.616

High

1342341

RCOR3
REST corepressor 3

3

20

High-throughput

0.616

High

1342358

DTNA
Dystrobrevin alpha

3

2

Small-scale

0.610

High

1256949

DOK4
Docking protein 4

3

3

High-throughput

0.609

High

278339

PIAS2
E3 SUMO-protein ligase PIAS2

2

5

High-throughput

0.606

High

380695

K2C1
Keratin, type II cytoskeletal 1

2

4

High-throughput

0.606

High

594638

PSB1
Proteasome subunit beta type-1

2

8

High-throughput

0.606

High

638579

RBTN1
Rhombotin-1

2

20

High-throughput

0.606

High

1186223

OLIG3
Oligodendrocyte transcription factor 3

2

5

High-throughput

0.606

High

1313366

TRAF4
TNF receptor-associated factor 4

2

13

High-throughput

0.606

High

1317561

BACH2
Transcription regulator protein BACH2

2

20

High-throughput

0.606

High

1342332

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

8

High-throughput

0.606

High

1342336

FX4L1
Forkhead box protein D4-like 1

2

20

High-throughput

0.606

High

1342357

ARIP4
Helicase ARIP4

2

20

High-throughput

0.606

High

1342333

ZC4H2
Zinc finger C4H2 domain-containing protein

2

0

High-throughput

0.602

High

1035602

SMAD4
Mothers against decapentaplegic homolog 4

2

6

Small-scale

0.600

High

917971

H4
Histone H4

2

14

High-throughput

0.584

High

918706

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.584

High

935263

H31
Histone H3.1

2

20

High-throughput

0.584

High

1301799

RANB9
Ran-binding protein 9

2

18

Small-scale

0.584

High

792007

HD
Huntingtin

1

4

High-throughput

0.582

High

1285923

CHP3
Calcineurin B homologous protein 3

1

2

High-throughput

0.582

High

1239374

SMYD1
Histone-lysine N-methyltransferase SMYD1

2

0

High-throughput

0.580

High

1293288

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1297412

CI072
Guanine nucleotide exchange factor C9orf72

2

0

High-throughput

0.580

High

1314049

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.580

High

1316046

DGC6L
Protein DGCR6L

2

0

High-throughput

0.580

High

1295543

CC136
Coiled-coil domain-containing protein 136

2

12

High-throughput

0.578

High

259624

HMMR
Hyaluronan mediated motility receptor

2

9

High-throughput

0.574

High

1033855

SNTA1
Alpha-1-syntrophin

2

4

High-throughput

0.574

High

1033925

SNTB2
Beta-2-syntrophin

2

4

High-throughput

0.574

High

1046451

SNTB1
Beta-1-syntrophin

2

3

High-throughput

0.574

High

1158579

L2GL2
LLGL scribble cell polarity complex component 2

2

7

High-throughput

0.574

High

1223944

RCOR2
REST corepressor 2

2

20

High-throughput

0.574

High

1342360

CEP83
Centrosomal protein of 83 kDa

2

11

High-throughput

0.574

High

726006

ADDA
Alpha-adducin

1

7

High-throughput

0.573

High

1190835

BRAP
BRCA1-associated protein

2

8

Small-scale

0.572

High

370492

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

329957

AGR2
Anterior gradient protein 2 homolog

2

2

High-throughput

0.553

High

814540

SYQ
Glutamine--tRNA ligase

2

2

High-throughput

0.553

High

849820

SUOX
Sulfite oxidase, mitochondrial

2

2

High-throughput

0.553

High

903848

NTF2
Nuclear transport factor 2

2

5

High-throughput

0.553

High

1044811

RIN1
Ras and Rab interactor 1

2

4

High-throughput

0.553

High

1205882

GPSM1
G-protein-signaling modulator 1

2

11

High-throughput

0.553

High

1236711

USBP1
Harmonin-binding protein USHBP1

2

10

High-throughput

0.553

High

1252496

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.553

High

1287666

DDT4L
DNA damage-inducible transcript 4-like protein

2

1

High-throughput

0.553

High

1313787

KIFC3
Kinesin-like protein KIFC3

2

2

High-throughput

0.553

High

1342334

PICK1
PRKCA-binding protein

2

1

High-throughput

0.553

High

1342335

TB22B
TBC1 domain family member 22B

2

1

High-throughput

0.553

High

277543

CCNK
Cyclin-K

1

6

High-throughput

0.541

High

843918

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.541

High

882989

RBM11
Splicing regulator RBM11

1

12

High-throughput

0.541

High

1044173

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

14

High-throughput

0.541

High

1342353

TF2AY
TFIIA-alpha and beta-like factor

1

1

High-throughput

0.541

High

1342359

RBM7
RNA-binding protein 7

1

11

High-throughput

0.541

High

71248

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

15

High-throughput

0.536

High

296145

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.536

High

358902

CRYAA
Alpha-crystallin A chain

1

4

High-throughput

0.536

High

455898

PARP1
Poly [ADP-ribose] polymerase 1

1

20

High-throughput

0.536

High

470568

H2A1
Histone H2A type 1

1

20

High-throughput

0.536

High

508727

TOP1
DNA topoisomerase 1

1

8

High-throughput

0.536

High

537081

TRI27
Zinc finger protein RFP

1

5

High-throughput

0.536

High

555655

H2AX
Histone H2AX

1

20

High-throughput

0.536

High

565040

HMGA1
High mobility group protein HMG-I/HMG-Y

1

4

High-throughput

0.536

High

682997

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

17

High-throughput

0.536

High

934498

CSK21
Casein kinase II subunit alpha

1

11

High-throughput

0.536

High

997917

RBBP4
Histone-binding protein RBBP4

1

20

High-throughput

0.536

High

1040014

DGKZ
Diacylglycerol kinase zeta

1

2

High-throughput

0.536

High

1083400

RBBP7
Histone-binding protein RBBP7

1

20

High-throughput

0.536

High

1087107

H2A2C
Histone H2A type 2-C

1

20

High-throughput

0.536

High

1087421

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

1131408

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

High-throughput

0.536

High

1151386

H2A2A
Histone H2A type 2-A

1

20

High-throughput

0.536

High

1167320

BCOR
BCL-6 corepressor

1

18

High-throughput

0.536

High

1191026

RAI1
Retinoic acid-induced protein 1

1

20

High-throughput

0.536

High

1205819

P66A
Transcriptional repressor p66-alpha

1

10

High-throughput

0.536

High

1263979

P66B
Transcriptional repressor p66-beta

1

10

High-throughput

0.536

High

1328683

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

1

High-throughput

0.536

High

1342343

MBD2
Methyl-CpG-binding domain protein 2

1

6

High-throughput

0.536

High

1342345

TCF20
Transcription factor 20

1

17

High-throughput

0.536

High

314893

FMNL1
Formin-like protein 1

1

1

High-throughput

0.523

High

825101

PTH2R
Parathyroid hormone 2 receptor

1

1

High-throughput

0.523

High

1297667

CFA53
Cilia- and flagella-associated protein 53

1

4

High-throughput

0.523

High

1342344

MO4L1
Mortality factor 4-like protein 1

1

1

High-throughput

0.515

High

146871

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.513

High

988137

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.513

High

1315451

HEMGN
Hemogen

1

1

Small-scale

0.504

High

1342355

FBX7
F-box only protein 7

1

3

High-throughput

0.501

High

500136

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.489

High

1270803

CBP
CREB-binding protein

1

20

Small-scale

0.481

High

1342350

DCTN4
Dynactin subunit 4

1

1

High-throughput

0.481

High

126174

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

16

High-throughput

0.479

High

135165

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

171084

TBXT
T-box transcription factor T

1

15

High-throughput

0.479

High

176284

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.479

High

181564

CLOCK
Circadian locomoter output cycles protein kaput

1

17

High-throughput

0.479

High

204437

MS18B
Protein Mis18-beta

1

1

High-throughput

0.479

High

211975

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

213389

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.479

High

244970

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.479

High

271793

PRDM1
PR domain zinc finger protein 1

1

8

High-throughput

0.479

High

295281

RECQ4
ATP-dependent DNA helicase Q4

1

13

High-throughput

0.479

High

309084

KI20A
Kinesin-like protein KIF20A

1

9

High-throughput

0.479

High

317521

YETS4
YEATS domain-containing protein 4

1

3

High-throughput

0.479

High

347960

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

379899

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

391917

H2A1B
Histone H2A type 1-B/E

1

20

High-throughput

0.479

High

443256

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

507513

ERG
Transcriptional regulator ERG

1

20

High-throughput

0.479

High

554520

GATA1
Erythroid transcription factor

1

19

High-throughput

0.479

High

570085

CEBPB
CCAAT/enhancer-binding protein beta

1

20

High-throughput

0.479

High

620210

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

620429

GATA2
Endothelial transcription factor GATA-2

1

19

High-throughput

0.479

High

620577

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

19

High-throughput

0.479

High

641570

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.479

High

658565

TEAD1
Transcriptional enhancer factor TEF-1

1

3

High-throughput

0.479

High

679177

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

707756

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.479

High

727595

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

828385

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

850202

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

6

High-throughput

0.479

High

898205

MAX
Protein max

1

20

High-throughput

0.479

High

952640

H33
Histone H3.3

1

20

High-throughput

0.479

High

988810

PAX8
Paired box protein Pax-8

1

20

High-throughput

0.479

High

1018271

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1021167

FOXC1
Forkhead box protein C1

1

20

High-throughput

0.479

High

1021354

FOXL1
Forkhead box protein L1

1

20

High-throughput

0.479

High

1063634

SUZ12
Polycomb protein SUZ12

1

3

High-throughput

0.479

High

1067153

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

1070653

RNPS1
RNA-binding protein with serine-rich domain 1

1

17

High-throughput

0.479

High

1080371

EZH2
Histone-lysine N-methyltransferase EZH2

1

17

High-throughput

0.479

High

1085188

TBR1
T-box brain protein 1

1

15

High-throughput

0.479

High

1160290

PKN3
Serine/threonine-protein kinase N3

1

8

High-throughput

0.479

High

1191149

I2BP2
Interferon regulatory factor 2-binding protein 2

1

5

Small-scale

0.479

High

1221753

SMC5
Structural maintenance of chromosomes protein 5

1

13

High-throughput

0.479

High

1229952

MIER1
Mesoderm induction early response protein 1

1

20

High-throughput

0.479

High

1235661

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

9

High-throughput

0.479

High

1254508

CCHCR
Coiled-coil alpha-helical rod protein 1

1

6

High-throughput

0.479

High

1254931

SP7
Transcription factor Sp7

1

16

High-throughput

0.479

High

1266692

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

1269686

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1281404

FBXW7
F-box/WD repeat-containing protein 7

1

14

High-throughput

0.479

High

1288324

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

20

High-throughput

0.479

High

1298999

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

7

High-throughput

0.479

High

1304706

FEV
Protein FEV

1

18

High-throughput

0.479

High

1306089

NP1L4
Nucleosome assembly protein 1-like 4

1

7

High-throughput

0.479

High

1312025

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.479

High

1315869

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.479

High

1318644

FOXQ1
Forkhead box protein Q1

1

20

High-throughput

0.479

High

1342305

GCM1
Chorion-specific transcription factor GCMa

1

3

High-throughput

0.479

High

1342349

RABX5
Rab5 GDP/GTP exchange factor

1

1

High-throughput

0.479

High

1342352

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

20

High-throughput

0.479

High

1342354

ASF1A
Histone chaperone ASF1A

1

2

High-throughput

0.479

High

1342356

ZN330
Zinc finger protein 330

1

4

High-throughput

0.479

High

1342361

SP16H
FACT complex subunit SPT16

1

10

High-throughput

0.479

High

995591

ECHP
Peroxisomal bifunctional enzyme

1

3

High-throughput

0.470

High

1081152

CCDC6
Coiled-coil domain-containing protein 6

1

9

High-throughput

0.470

High

1311960

TCHP
Trichoplein keratin filament-binding protein

1

3

High-throughput

0.470

High

122239

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.458

High

254009

MTG16
Protein CBFA2T3

1

0

Small-scale

0.458

High

471662

TFPT
TCF3 fusion partner

1

0

High-throughput

0.458

High

1110503

GON4L
GON-4-like protein

1

0

High-throughput

0.458

High

1157617

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.458

High

1289766

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.458

High

989134

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.457

High

207837

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

3

High-throughput

0.439

High

1342339

TREM2
Triggering receptor expressed on myeloid cells 2

1

0

High-throughput

0.438

High

878469

PAX9
Paired box protein Pax-9

1

20

High-throughput

0.437

High

1050159

GIT2
ARF GTPase-activating protein GIT2

1

5

High-throughput

0.437

High

1118364

GRAP1
GRIP1-associated protein 1

1

6

High-throughput

0.437

High

1121556

EIPR1
EARP and GARP complex-interacting protein 1

1

20

High-throughput

0.437

High

1122615

CCD93
Coiled-coil domain-containing protein 93

1

3

High-throughput

0.437

High

1155881

PHLB3
Pleckstrin homology-like domain family B member 3

1

6

High-throughput

0.437

High

1205139

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

9

High-throughput

0.437

High

1252313

GOGA5
Golgin subfamily A member 5

1

9

High-throughput

0.437

High

1317803

NUF2
Kinetochore protein Nuf2

1

12

High-throughput

0.437

High

1342338

RM39
Large ribosomal subunit protein mL39

1

1

High-throughput

0.437

High

1342342

HECW2
E3 ubiquitin-protein ligase HECW2

1

14

High-throughput

0.437

High

484203

CALM3
Calmodulin-3

1

0

High-throughput

0.426

High

3300

A0A0S2Z528
Proline-serine-threonine phosphatase interacting protein 1 isoform 3

1

3

High-throughput

0.417

High

3320

A0A0S2Z5D5
Dynactin 4 isoform 3

1

1

High-throughput

0.417

High

1286288

SYTL4
Synaptotagmin-like protein 4

4

0

High-throughput

0.364

High

740696

HPCL1
Hippocalcin-like protein 1

2

0

High-throughput

0.337

High

1216765

TPPC5
Trafficking protein particle complex subunit 5

2

0

High-throughput

0.316

High

1251178

G45IP
Large ribosomal subunit protein mL64

2

0

High-throughput

0.316

High

1292332

CEP95
Centrosomal protein of 95 kDa

2

0

High-throughput

0.316

High

1297325

LURA1
Leucine rich adaptor protein 1

2

0

High-throughput

0.316

High

1342337

T11L1
T-complex protein 11-like protein 1

2

0

High-throughput

0.316

High

1342348

PS1C2
Psoriasis susceptibility 1 candidate gene 2 protein

2

0

High-throughput

0.316

High

1328847

RSPH9
Radial spoke head protein 9 homolog

1

0

High-throughput

0.299

High

535944

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.279

Low

1149998

BLT3A
Bridge-like lipid transfer protein family member 3A

1

0

High-throughput

0.279

Low

942566

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.268

Low

1046964

BYST
Bystin

1

0

High-throughput

0.268

Low

1219488

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

0

High-throughput

0.268

Low

81765

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.249

Low

1137650

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

0

High-throughput

0.249

Low

1146188

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1190414

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.249

Low

1295152

VPS50
Syndetin

1

0

High-throughput

0.249

Low

1336162

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.249

Low

1342227

TUFT1
Tuftelin

1

0

High-throughput

0.249

Low

1342347

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024