Protein: PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

Gene: PTMA
Organism: Homo sapiens
Interactions: 153
UniProt ID: P06454

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006351 - DNA-templated transcription
GO:0042393 - histone binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

414625

KEAP1
Kelch-like ECH-associated protein 1

6

2

Small-scale

0.738

High

414629

ELAV1
ELAV-like protein 1

5

0

Small-scale

0.672

High

414618

EP300
Histone acetyltransferase p300

2

2

Small-scale

0.629

High

233145

NUPR1
Nuclear protein 1

2

0

Small-scale

0.620

High

414545

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

4

Small-scale

0.584

High

414567

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

2

3

Small-scale

0.584

High

414587

CCNF
Cyclin-F

2

1

High-throughput

0.584

High

414602

ACTB
Actin, cytoplasmic 1

2

3

Small-scale

0.584

High

414610

ACTC
Actin, alpha cardiac muscle 1

2

3

High-throughput

0.584

High

414634

FTM
Protein fantom

2

2

High-throughput

0.571

High

414649

CBP
CREB-binding protein

1

2

Small-scale

0.561

High

414653

PHB2
Prohibitin-2

1

1

Small-scale

0.552

High

414635

RHGBA
Rho GTPase-activating protein 11A

2

0

High-throughput

0.547

High

414661

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.543

High

414598

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.541

High

414628

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.541

High

170213

TIF1A
Transcription intermediary factor 1-alpha

1

2

High-throughput

0.536

High

414577

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.536

High

414589

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

414597

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.536

High

414612

CDK17
Cyclin-dependent kinase 17

1

2

High-throughput

0.536

High

414644

KLHL7
Kelch-like protein 7

1

2

High-throughput

0.536

High

414665

UBQL1
Ubiquilin-1

1

3

High-throughput

0.515

High

176346

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

High-throughput

0.513

High

414544

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

414552

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

414592

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.513

High

414593

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

414608

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

0

High-throughput

0.513

High

414611

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.513

High

414620

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.513

High

414636

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

0

High-throughput

0.513

High

414637

CC137
Coiled-coil domain-containing protein 137

1

0

High-throughput

0.513

High

414639

APTX
Aprataxin

1

0

High-throughput

0.513

High

414654

ARI3A
AT-rich interactive domain-containing protein 3A

1

0

High-throughput

0.513

High

414659

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.513

High

414660

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.513

High

414666

DDX52
Probable ATP-dependent RNA helicase DDX52

1

0

High-throughput

0.513

High

414594

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.508

High

414585

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.506

High

414614

SET
Protein SET

1

0

Small-scale

0.506

High

261373

NCOR1
Nuclear receptor corepressor 1

1

2

Small-scale

0.501

High

414619

HDAC1
Histone deacetylase 1

1

1

Small-scale

0.501

High

414648

HDAC2
Histone deacetylase 2

1

1

Small-scale

0.501

High

316769

KLF8
Krueppel-like factor 8

1

1

High-throughput

0.500

High

414655

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.500

High

414667

MTCL1
Microtubule cross-linking factor 1

1

3

High-throughput

0.489

High

368819

ESR1
Estrogen receptor

1

0

Small-scale

0.480

High

414652

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.480

High

235667

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

High-throughput

0.479

High

302658

ARHGF
Rho guanine nucleotide exchange factor 15

1

1

High-throughput

0.479

High

359451

K2C6A
Keratin, type II cytoskeletal 6A

1

3

Small-scale

0.479

High

380535

K2C1
Keratin, type II cytoskeletal 1

1

2

Small-scale

0.479

High

414540

K1C19
Keratin, type I cytoskeletal 19

1

4

Small-scale

0.479

High

414541

K1C16
Keratin, type I cytoskeletal 16

1

4

Small-scale

0.479

High

414547

BIP
Endoplasmic reticulum chaperone BiP

1

3

Small-scale

0.479

High

414548

HSP7C
Heat shock cognate 71 kDa protein

1

2

Small-scale

0.479

High

414554

K1C10
Keratin, type I cytoskeletal 10

1

5

Small-scale

0.479

High

414555

K2C5
Keratin, type II cytoskeletal 5

1

2

Small-scale

0.479

High

414561

HSP76
Heat shock 70 kDa protein 6

1

2

Small-scale

0.479

High

414572

PDIA3
Protein disulfide-isomerase A3

1

1

High-throughput

0.479

High

414575

HS71L
Heat shock 70 kDa protein 1-like

1

2

Small-scale

0.479

High

414576

CTNB1
Catenin beta-1

1

2

High-throughput

0.479

High

414578

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

414579

K1C9
Keratin, type I cytoskeletal 9

1

4

Small-scale

0.479

High

414580

MYH9
Myosin-9

1

2

Small-scale

0.479

High

414581

MYH10
Myosin-10

1

2

Small-scale

0.479

High

414582

K22E
Keratin, type II cytoskeletal 2 epidermal

1

3

Small-scale

0.479

High

414583

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.479

High

414584

GRP75
Stress-70 protein, mitochondrial

1

4

Small-scale

0.479

High

414590

BAG6
Large proline-rich protein BAG6

1

4

High-throughput

0.479

High

414595

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

3

Small-scale

0.479

High

414599

HDAC4
Histone deacetylase 4

1

2

High-throughput

0.479

High

414606

ACTA
Actin, aortic smooth muscle

1

3

High-throughput

0.479

High

414609

ACTG
Actin, cytoplasmic 2

1

3

High-throughput

0.479

High

414617

SRSF4
Serine/arginine-rich splicing factor 4

1

1

High-throughput

0.479

High

414623

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

4

Small-scale

0.479

High

414664

TBK1
Serine/threonine-protein kinase TBK1

1

1

High-throughput

0.479

High

129641

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

150817

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

202359

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.458

High

302787

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

336304

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

340350

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.458

High

401262

JUN
Transcription factor Jun

1

0

High-throughput

0.458

High

414538

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

414539

PROF1
Profilin-1

1

0

High-throughput

0.458

High

414543

RET1
Retinol-binding protein 1

1

0

High-throughput

0.458

High

414551

KCRB
Creatine kinase B-type

1

0

High-throughput

0.458

High

414557

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

414558

ENPL
Endoplasmin

1

0

High-throughput

0.458

High

414560

STMN1
Stathmin

1

0

High-throughput

0.458

High

414562

TAL1
T-cell acute lymphocytic leukemia protein 1

1

0

High-throughput

0.458

High

414564

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

Small-scale

0.458

High

414565

PTMS
Parathymosin

1

0

High-throughput

0.458

High

414568

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.458

High

414570

CALR
Calreticulin

1

0

High-throughput

0.458

High

414573

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

0

Small-scale

0.458

High

414574

1433B
14-3-3 protein beta/alpha

1

0

Small-scale

0.458

High

414586

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

414588

VDAC2
Voltage-dependent anion-selective channel protein 2

1

0

Small-scale

0.458

High

414591

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

414601

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

414603

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

414605

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.458

High

414613

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

414615

MEF2A
Myocyte-specific enhancer factor 2A

1

0

High-throughput

0.458

High

414616

H11
Histone H1.1

1

0

Small-scale

0.458

High

414621

CUL3
Cullin-3

1

0

High-throughput

0.458

High

414622

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

414630

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

414632

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.458

High

414633

PAP1M
Polyadenylate-binding protein 1-like 2

1

0

High-throughput

0.458

High

414638

BRWD3
Bromodomain and WD repeat-containing protein 3

1

0

High-throughput

0.458

High

414640

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

414645

YAF2
YY1-associated factor 2

1

0

High-throughput

0.458

High

414647

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

0

High-throughput

0.458

High

414656

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

414658

RHG39
Rho GTPase-activating protein 39

1

0

High-throughput

0.458

High

414662

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

414663

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

414537

CDK1
Cyclin-dependent kinase 1

1

2

Small-scale

0.445

High

414549

CDK4
Cyclin-dependent kinase 4

1

2

Small-scale

0.445

High

414569

CDK2
Cyclin-dependent kinase 2

1

2

Small-scale

0.445

High

414596

IMA1
Importin subunit alpha-1

1

1

Small-scale

0.445

High

414657

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

414642

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.439

High

414556

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.437

High

414668

MYH4
Myosin-4

1

2

High-throughput

0.437

High

414546

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

414550

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.426

High

414559

CCNB1
G2/mitotic-specific cyclin-B1

1

0

Small-scale

0.426

High

414563

RCC1
Regulator of chromosome condensation

1

0

Small-scale

0.426

High

414600

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

414607

RAN
GTP-binding nuclear protein Ran

1

0

Small-scale

0.426

High

414627

IMB1
Importin subunit beta-1

1

0

Small-scale

0.426

High

414650

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

3304

A0A0S2Z547
Rho guanine nucleotide exchange factor 15 isoform 1

1

1

High-throughput

0.407

High

108961

H0YLW0
Signal recognition particle 14

1

1

High-throughput

0.407

High

414542

RM03
Large ribosomal subunit protein uL3m

1

0

High-throughput

0.279

Low

414631

KNOP1
Lysine-rich nucleolar protein 1

1

0

High-throughput

0.279

Low

414651

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

414566

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

414626

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

414669

Q9Y649
GW128

1

0

High-throughput

0.268

Low

329237

AGR2
Anterior gradient protein 2 homolog

1

0

Small-scale

0.249

Low

414553

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.249

Low

414571

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.249

Low

414604

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.249

Low

414624

SEPT6
Septin-6

1

0

High-throughput

0.249

Low

414641

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

414643

SL9A9
Sodium/hydrogen exchanger 9

1

0

Small-scale

0.249

Low

414646

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024