Protein: IQEC1
IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein) (BRAG2)

Gene: IQEC1, IQSEC1
Organism: Homo sapiens
Interactions: 117
UniProt ID: Q6DN90

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005730 - nucleolus
GO:0008021 - synaptic vesicle
GO:0008289 - lipid binding
GO:0014069 - postsynaptic density

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1128313

IQEC2
IQ motif and SEC7 domain-containing protein 2

1

8

High-throughput

0.665

High

840731

DYN2
Dynamin-2

1

1

High-throughput

0.665

High

912959

ARF6
ADP-ribosylation factor 6

1

16

High-throughput

0.618

High

1031219

SKP2
S-phase kinase-associated protein 2

2

0

High-throughput

0.602

High

1150523

INSY2
Inhibitory synaptic factor 2A

2

0

High-throughput

0.602

High

1150553

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

2

7

High-throughput

0.574

High

1150560

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.553

High

716715

CTNA1
Catenin alpha-1

1

1

Small-scale

0.552

High

180044

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

1

High-throughput

0.536

High

258070

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.536

High

863834

LIMK2
LIM domain kinase 2

1

1

High-throughput

0.536

High

904710

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

1150531

LRC25
Leucine-rich repeat-containing protein 25

1

2

High-throughput

0.536

High

1150544

ANM6
Protein arginine N-methyltransferase 6

1

5

High-throughput

0.536

High

1150554

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

1

High-throughput

0.536

High

152000

TOR1A
Torsin-1A

1

3

High-throughput

0.534

High

227762

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.534

High

1051323

DCTN1
Dynactin subunit 1

1

2

High-throughput

0.534

High

837616

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

2

3

Small-scale

0.533

High

3356

A0A0S2Z5Q7
Alsin Rho guanine nucleotide exchange factor ALS2

1

2

High-throughput

0.515

High

394924

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.515

High

1150555

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.515

High

245700

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

438781

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.513

High

968849

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

1150545

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1150562

B2L12
Bcl-2-like protein 12

1

0

High-throughput

0.513

High

1025790

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.511

High

47236

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.493

High

742350

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

834301

PSN1
Presenilin-1

1

0

High-throughput

0.493

High

868547

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

1150536

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

0

High-throughput

0.493

High

1150539

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

166950

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

2

High-throughput

0.489

High

197902

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

1

High-throughput

0.489

High

296454

ACL6B
Actin-like protein 6B

1

2

High-throughput

0.489

High

796110

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.489

High

1101720

CF184
Cilia- and flagella-associated protein 184

1

1

High-throughput

0.489

High

1150527

ST32C
Serine/threonine-protein kinase 32C

1

1

High-throughput

0.489

High

1150533

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

1150541

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.489

High

1150552

NPAS1
Neuronal PAS domain-containing protein 1

1

3

High-throughput

0.489

High

1150566

LATS2
Serine/threonine-protein kinase LATS2

1

2

High-throughput

0.489

High

1150570

HSPB8
Heat shock protein beta-8

1

1

High-throughput

0.489

High

1150573

ASB4
Ankyrin repeat and SOCS box protein 4

1

7

High-throughput

0.489

High

162868

XPO1
Exportin-1

1

1

High-throughput

0.479

High

347046

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

1036659

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

1150547

ALS2
Alsin

1

1

High-throughput

0.479

High

1150551

DNJC7
DnaJ homolog subfamily C member 7

1

3

High-throughput

0.479

High

1150563

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

1150569

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

779589

CCNF
Cyclin-F

1

1

High-throughput

0.470

High

848399

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.470

High

456589

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

1

High-throughput

0.470

High

361494

APOE
Apolipoprotein E

1

0

High-throughput

0.460

High

1150571

AGO2
Protein argonaute-2

1

0

High-throughput

0.458

High

883536

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

7

High-throughput

0.445

High

1150546

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

6

High-throughput

0.445

High

1150548

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

9

High-throughput

0.445

High

1150556

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

8

High-throughput

0.445

High

1150557

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

2

High-throughput

0.445

High

1150558

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

2

High-throughput

0.445

High

795765

MAGA3
Melanoma-associated antigen 3

1

2

High-throughput

0.439

High

164398

TRI66
Tripartite motif-containing protein 66

1

2

High-throughput

0.437

High

374389

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.437

High

903300

WDR5
WD repeat-containing protein 5

1

3

Small-scale

0.437

High

915754

RHOB
Rho-related GTP-binding protein RhoB

1

11

High-throughput

0.437

High

941039

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

1021514

DLG1
Disks large homolog 1

1

6

Small-scale

0.437

High

1046072

DX39B
Spliceosome RNA helicase DDX39B

1

1

High-throughput

0.437

High

1150524

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

1150529

SLX4
Structure-specific endonuclease subunit SLX4

1

1

High-throughput

0.437

High

1150532

RHG18
Rho GTPase-activating protein 18

1

3

High-throughput

0.437

High

1150542

RNF31
E3 ubiquitin-protein ligase RNF31

1

5

High-throughput

0.437

High

1150549

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.437

High

1150559

Q9H4D1
Protein kinase

1

7

High-throughput

0.437

High

1150561

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.437

High

1150564

CENPJ
Centromere protein J

1

1

High-throughput

0.437

High

708950

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.426

High

1150572

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

240046

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

1150526

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

1

High-throughput

0.407

High

1150535

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

876606

AF17
Protein AF-17

2

0

High-throughput

0.328

High

1125914

TFDP3
Transcription factor Dp family member 3

2

0

High-throughput

0.318

High

234659

BRNP1
BMP/retinoic acid-inducible neural-specific protein 1

1

0

High-throughput

0.279

Low

277316

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.279

Low

441617

TRFM
Melanotransferrin

1

0

High-throughput

0.279

Low

612109

PROZ
Vitamin K-dependent protein Z

1

0

High-throughput

0.279

Low

645977

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

923879

CCG7
Voltage-dependent calcium channel gamma-7 subunit

1

0

High-throughput

0.279

Low

1131699

DACT2
Dapper homolog 2

1

0

High-throughput

0.279

Low

1132234

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.279

Low

1150528

FA83A
Protein FAM83A

1

0

High-throughput

0.279

Low

1150530

PELI3
E3 ubiquitin-protein ligase pellino homolog 3

1

0

High-throughput

0.279

Low

1150537

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.279

Low

1150538

BSND
Barttin

1

0

High-throughput

0.279

Low

1150540

IRF7
Interferon regulatory factor 7

1

0

High-throughput

0.279

Low

1150543

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

1150565

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

1150568

FBLN5
Fibulin-5

1

0

High-throughput

0.279

Low

336523

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.278

Low

344504

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.268

Low

791659

HD
Huntingtin

1

0

High-throughput

0.268

Low

848053

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.268

Low

1084809

SMN
Survival motor neuron protein

1

0

High-throughput

0.268

Low

1150525

PEX26
Peroxisome assembly protein 26

1

0

High-throughput

0.268

Low

1150550

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.268

Low

824105

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

928616

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.249

Low

1069307

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.249

Low

1101111

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1150534

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1150567

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.249

Low

1150574

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024