Protein: LONP2
Lon protease homolog 2, peroxisomal (EC 3.4.21.53) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease) (pLon)

Gene: LONP2
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q86WA8

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0004176 - ATP-dependent peptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

227946

PRKN
E3 ubiquitin-protein ligase parkin

2

20

High-throughput

0.754

High

1034479

OS9
Protein OS-9

3

0

High-throughput

0.646

High

840280

PEX5
Peroxisomal targeting signal 1 receptor

3

4

Small-scale

0.631

High

655184

IL1R2
Interleukin-1 receptor type 2

2

1

High-throughput

0.628

High

1022931

CDC16
Cell division cycle protein 16 homolog

2

3

High-throughput

0.628

High

1203064

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

2

3

High-throughput

0.628

High

326701

SNAI1
Zinc finger protein SNAI1

1

3

High-throughput

0.618

High

1203054

MA7D2
MAP7 domain-containing protein 2

2

5

High-throughput

0.574

High

1203061

TMOD3
Tropomodulin-3

2

1

High-throughput

0.574

High

1203068

PCDA4
Protocadherin alpha-4

2

5

High-throughput

0.574

High

1203069

PCDAC
Protocadherin alpha-12

2

5

High-throughput

0.574

High

1203071

PCDA9
Protocadherin alpha-9

2

5

High-throughput

0.574

High

167097

ARHGB
Rho guanine nucleotide exchange factor 11

2

2

High-throughput

0.571

High

369934

ESR1
Estrogen receptor

2

14

High-throughput

0.571

High

1203052

RBCC1
RB1-inducible coiled-coil protein 1

2

4

High-throughput

0.571

High

373400

CATA
Catalase

2

0

High-throughput

0.563

High

125559

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

7

High-throughput

0.536

High

801227

KI67
Proliferation marker protein Ki-67

1

5

High-throughput

0.536

High

863784

LIMK1
LIM domain kinase 1

1

7

High-throughput

0.536

High

1085422

MK06
Mitogen-activated protein kinase 6

1

10

High-throughput

0.536

High

1203050

KIBRA
Protein KIBRA

1

9

High-throughput

0.536

High

1203058

WNK1
Serine/threonine-protein kinase WNK1

1

8

High-throughput

0.536

High

1203067

NXT1
NTF2-related export protein 1

1

3

High-throughput

0.536

High

1203070

NEUR2
Sialidase-2

1

1

High-throughput

0.536

High

1118980

AMOT
Angiomotin

1

6

High-throughput

0.515

High

200402

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.513

High

610670

IBP4
Insulin-like growth factor-binding protein 4

1

0

High-throughput

0.513

High

372960

C4BPA
C4b-binding protein alpha chain

1

4

High-throughput

0.489

High

1203063

RN181
E3 ubiquitin-protein ligase RNF181

1

3

High-throughput

0.489

High

1203072

PCDA8
Protocadherin alpha-8

1

5

High-throughput

0.489

High

1203073

PCDA3
Protocadherin alpha-3

1

5

High-throughput

0.489

High

1203074

PCDAB
Protocadherin alpha-11

1

5

High-throughput

0.489

High

116594

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

1

High-throughput

0.479

High

1064457

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

1203053

ESR2
Estrogen receptor beta

1

14

High-throughput

0.479

High

1203060

MTMRA
Myotubularin-related protein 10

1

1

High-throughput

0.479

High

1203062

WWOX
WW domain-containing oxidoreductase

1

5

High-throughput

0.479

High

1203066

FBW1B
F-box/WD repeat-containing protein 11

1

12

High-throughput

0.479

High

162945

XPO1
Exportin-1

1

1

High-throughput

0.445

High

1102552

TYSD1
Peroxisomal leader peptide-processing protease

1

5

Small-scale

0.445

High

1203056

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

6

High-throughput

0.445

High

100913

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

1170651

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

1203059

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

1150270

TBC3G
TBC1 domain family member 3G

1

1

High-throughput

0.407

High

1203057

RSPH9
Radial spoke head protein 9 homolog

4

0

High-throughput

0.363

High

1083091

IL17
Interleukin-17A

3

0

High-throughput

0.347

High

1203065

DKK3
Dickkopf-related protein 3

2

0

High-throughput

0.328

High

319592

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

1147390

OLM2B
Olfactomedin-like protein 2B

1

0

High-throughput

0.279

Low

1166411

LYPD2
Ly6/PLAUR domain-containing protein 2

1

0

High-throughput

0.279

Low

1203055

RETNB
Resistin-like beta

1

0

High-throughput

0.279

Low

1203051

SYCE1
Synaptonemal complex central element protein 1

1

0

High-throughput

0.268

Low

429279

PGS2
Decorin

1

0

High-throughput

0.249

Low

83372

RBRP
Putative RNA-binding regulatory peptide

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024