Protein: VAMP2
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)

Gene: VAMP2
Organism: Homo sapiens
Interactions: 148
UniProt ID: P63027

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005516 - calmodulin binding
GO:0005543 - phospholipid binding
GO:0005802 - trans-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

926202

STX4
Syntaxin-4

10

20

Small-scale

0.973

High

926213

STX1A
Syntaxin-1A

10

20

Small-scale

0.971

High

926203

STX3
Syntaxin-3

5

20

Small-scale

0.923

High

178472

STX7
Syntaxin-7

4

20

High-throughput

0.895

High

699254

STX2
Syntaxin-2

4

20

Small-scale

0.885

High

269406

STX11
Syntaxin-11

3

20

Small-scale

0.866

High

873528

SNAA
Alpha-soluble NSF attachment protein

3

20

Small-scale

0.866

High

926226

STX12
Syntaxin-12

3

20

High-throughput

0.861

High

926230

STX19
Syntaxin-19

3

20

High-throughput

0.861

High

898830

STX1B
Syntaxin-1B

3

20

Small-scale

0.845

High

926210

VAMP3
Vesicle-associated membrane protein 3

2

17

Small-scale

0.799

High

212790

STX6
Syntaxin-6

2

20

High-throughput

0.789

High

893268

SNP25
Synaptosomal-associated protein 25

6

20

Small-scale

0.721

High

742201

SYUA
Alpha-synuclein

4

1

Small-scale

0.702

High

118017

SNP23
Synaptosomal-associated protein 23

4

20

Small-scale

0.698

High

926249

SNAG
Gamma-soluble NSF attachment protein

1

20

High-throughput

0.691

High

926267

STX8
Syntaxin-8

1

20

High-throughput

0.691

High

926212

SYPL1
Synaptophysin-like protein 1

3

6

High-throughput

0.675

High

926227

WDFY1
WD repeat and FYVE domain-containing protein 1

3

6

High-throughput

0.675

High

926250

VAMP8
Vesicle-associated membrane protein 8

1

14

Small-scale

0.647

High

320300

SNP29
Synaptosomal-associated protein 29

2

20

High-throughput

0.644

High

926236

TPC2
Two pore channel protein 2

2

2

High-throughput

0.628

High

620263

VAMP1
Vesicle-associated membrane protein 1

1

18

High-throughput

0.618

High

364239

TFR1
Transferrin receptor protein 1

2

4

High-throughput

0.611

High

874800

TERA
Transitional endoplasmic reticulum ATPase

2

1

Small-scale

0.606

High

926205

AQP6
Aquaporin-6

2

9

High-throughput

0.606

High

926208

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

4

High-throughput

0.606

High

926216

AR13B
ADP-ribosylation factor-like protein 13B

2

20

High-throughput

0.606

High

926222

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

9

High-throughput

0.606

High

926228

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

3

High-throughput

0.606

High

926231

JAGN1
Protein jagunal homolog 1

2

2

High-throughput

0.606

High

926232

TM86B
Lysoplasmalogenase TMEM86B

2

3

High-throughput

0.606

High

926237

S7A14
Solute carrier family 7 member 14

2

1

High-throughput

0.606

High

926243

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

4

High-throughput

0.606

High

926245

TM101
Transmembrane protein 101

2

1

High-throughput

0.606

High

926258

SCN3B
Sodium channel regulatory subunit beta-3

2

7

High-throughput

0.606

High

926269

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

14

High-throughput

0.606

High

349234

RASH
GTPase HRas

2

20

High-throughput

0.584

High

350050

RASK
GTPase KRas

2

20

High-throughput

0.584

High

506961

LAMP1
Lysosome-associated membrane glycoprotein 1

2

20

High-throughput

0.584

High

681219

SC6A4
Sodium-dependent serotonin transporter

1

3

Small-scale

0.578

High

156109

CPLX1
Complexin-1

1

3

Small-scale

0.575

High

296517

KPCD3
Serine/threonine-protein kinase D3

1

1

Small-scale

0.573

High

496791

TAU
Microtubule-associated protein tau

2

9

High-throughput

0.571

High

682420

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

2

High-throughput

0.553

High

926219

MARH8
E3 ubiquitin-protein ligase MARCHF8

2

6

High-throughput

0.553

High

926233

KASH5
Protein KASH5

2

2

High-throughput

0.553

High

926254

CERS4
Ceramide synthase 4

2

1

High-throughput

0.553

High

926255

AT132
Polyamine-transporting ATPase 13A2

1

18

Small-scale

0.541

High

200214

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

1

High-throughput

0.536

High

282212

SEGN
Secretagogin

1

4

High-throughput

0.536

High

439113

SYPH
Synaptophysin

1

6

High-throughput

0.536

High

554293

MUC1
Mucin-1

1

4

High-throughput

0.536

High

572338

LEG3
Galectin-3

1

2

High-throughput

0.536

High

803893

NSF
Vesicle-fusing ATPase

1

10

High-throughput

0.536

High

926204

UT1
Urea transporter 1

1

1

High-throughput

0.536

High

926211

RB11B
Ras-related protein Rab-11B

1

20

High-throughput

0.536

High

926257

CENPM
Centromere protein M

1

2

High-throughput

0.536

High

926265

PRAF1
Prenylated Rab acceptor protein 1

1

1

Small-scale

0.527

High

636301

DNJB1
DnaJ homolog subfamily B member 1

1

0

High-throughput

0.513

High

926207

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

926235

T185A
Transmembrane protein 185A

1

0

High-throughput

0.513

High

926270

NTNG1
Netrin-G1

1

0

High-throughput

0.513

High

119628

STXB3
Syntaxin-binding protein 3

1

17

Small-scale

0.501

High

237961

EXOC3
Exocyst complex component 3

1

1

Small-scale

0.501

High

310594

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

9

Small-scale

0.501

High

475595

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.501

High

803480

BAG6
Large proline-rich protein BAG6

1

5

Small-scale

0.501

High

847435

BAP31
B-cell receptor-associated protein 31

1

3

Small-scale

0.501

High

926252

DNJC5
DnaJ homolog subfamily C member 5

1

8

High-throughput

0.501

High

926260

VAPA
Vesicle-associated membrane protein-associated protein A

1

9

Small-scale

0.501

High

359837

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

11

High-throughput

0.481

High

926218

TMM31
Transmembrane protein 31

1

2

High-throughput

0.481

High

132445

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

4

High-throughput

0.479

High

159947

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

11

Small-scale

0.479

High

163787

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

15

High-throughput

0.479

High

205253

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.479

High

279506

FLOT1
Flotillin-1

1

3

High-throughput

0.479

High

305407

ZFPL1
Zinc finger protein-like 1

1

3

High-throughput

0.479

High

318097

DIRA3
GTP-binding protein Di-Ras3

1

15

High-throughput

0.479

High

348604

RASN
GTPase NRas

1

20

High-throughput

0.479

High

433686

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.479

High

436247

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

525896

IFM1
Interferon-induced transmembrane protein 1

1

7

High-throughput

0.479

High

527385

LAMP2
Lysosome-associated membrane glycoprotein 2

1

20

High-throughput

0.479

High

545311

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

566999

CXA1
Gap junction alpha-1 protein

1

13

High-throughput

0.479

High

591541

RAB3B
Ras-related protein Rab-3B

1

16

High-throughput

0.479

High

591808

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.479

High

592192

RAB5A
Ras-related protein Rab-5A

1

20

High-throughput

0.479

High

594733

ATP4A
Potassium-transporting ATPase alpha chain 1

1

16

Small-scale

0.479

High

599560

SYT1
Synaptotagmin-1

1

4

Small-scale

0.479

High

648713

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

669971

MARCS
Myristoylated alanine-rich C-kinase substrate

1

9

High-throughput

0.479

High

793263

MUC18
Cell surface glycoprotein MUC18

1

4

High-throughput

0.479

High

844474

RAB5C
Ras-related protein Rab-5C

1

20

High-throughput

0.479

High

844864

RAB7A
Ras-related protein Rab-7a

1

20

High-throughput

0.479

High

845430

RAB9A
Ras-related protein Rab-9A

1

20

High-throughput

0.479

High

893880

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

895029

RAB2A
Ras-related protein Rab-2A

1

20

High-throughput

0.479

High

900359

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

912840

ARF6
ADP-ribosylation factor 6

1

9

High-throughput

0.479

High

913996

RB11A
Ras-related protein Rab-11A

1

14

High-throughput

0.479

High

915589

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

925171

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

926198

CXAR
Coxsackievirus and adenovirus receptor

1

3

High-throughput

0.479

High

926199

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

926200

IFM3
Interferon-induced transmembrane protein 3

1

7

High-throughput

0.479

High

926201

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

926209

RAB35
Ras-related protein Rab-35

1

16

High-throughput

0.479

High

926214

OCLN
Occludin

1

2

High-throughput

0.479

High

926220

LTOR1
Ragulator complex protein LAMTOR1

1

5

High-throughput

0.479

High

926223

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

926224

TM11B
Transmembrane protease serine 11B

1

4

High-throughput

0.479

High

926229

CXD3
Gap junction delta-3 protein

1

13

High-throughput

0.479

High

926234

DHB11
Estradiol 17-beta-dehydrogenase 11

1

9

High-throughput

0.479

High

926238

LPAR1
Lysophosphatidic acid receptor 1

1

2

High-throughput

0.479

High

926239

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

926240

GOGA1
Golgin subfamily A member 1

1

1

High-throughput

0.479

High

926241

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

14

High-throughput

0.479

High

926247

FMNL2
Formin-like protein 2

1

3

High-throughput

0.479

High

926248

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

926253

TMT1A
Thiol S-methyltransferase TMT1A

1

4

High-throughput

0.479

High

926256

TMPS4
Transmembrane protease serine 4

1

4

High-throughput

0.479

High

926259

ELOV5
Very long chain fatty acid elongase 5

1

10

High-throughput

0.479

High

926261

TM216
Transmembrane protein 216

1

3

High-throughput

0.479

High

926262

ANFY1
Rabankyrin-5

1

3

High-throughput

0.479

High

926263

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

6

High-throughput

0.479

High

926268

LAMP3
Lysosome-associated membrane glycoprotein 3

1

20

High-throughput

0.479

High

575364

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

926215

DGUOK
Deoxyguanosine kinase, mitochondrial

1

0

High-throughput

0.458

High

210896

GET3
ATPase GET3

1

1

Small-scale

0.457

High

86503

WASH3
Putative WAS protein family homolog 3

1

2

High-throughput

0.445

High

239914

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

11

High-throughput

0.445

High

486503

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

2

High-throughput

0.437

High

569555

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.437

High

926221

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

926225

TMM17
Transmembrane protein 17

1

6

High-throughput

0.437

High

926242

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

926244

TECT2
Tectonic-2

1

5

High-throughput

0.437

High

926251

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

4

High-throughput

0.437

High

926266

PPM1H
Protein phosphatase 1H

1

1

High-throughput

0.437

High

926206

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

926246

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.426

High

926217

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

2

0

High-throughput

0.316

High

926271

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

645849

FKBP2
Peptidyl-prolyl cis-trans isomerase FKBP2

1

0

Small-scale

0.261

Low

926264

NUFP1
FMR1-interacting protein NUFIP1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024