Protein: ANGT
Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II); Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV); Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4]

Gene: ANGT, AGT
Organism: Homo sapiens
Interactions: 40
UniProt ID: P01019

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0001819 - positive regulation of cytokine production
GO:0001822 - kidney development
GO:0001974 - blood vessel remodeling
GO:0002016 - regulation of blood volume by renin-angiotensin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341605

RENI
Renin

2

1

Small-scale

0.841

High

198329

KLK10
Kallikrein-10

1

20

High-throughput

0.691

High

344382

ACE2
Angiotensin-converting enzyme 2

3

4

Small-scale

0.672

High

344361

ACE
Angiotensin-converting enzyme

3

4

Small-scale

0.646

High

344360

BIP
Endoplasmic reticulum chaperone BiP

2

10

High-throughput

0.628

High

344362

CALX
Calnexin

2

6

High-throughput

0.628

High

344369

AGTR2
Type-2 angiotensin II receptor

2

13

Small-scale

0.595

High

204895

TGON2
Trans-Golgi network integral membrane protein 2

2

3

High-throughput

0.549

High

344383

Q9H4D1
Protein kinase

2

8

High-throughput

0.533

High

153525

ANM5
Protein arginine N-methyltransferase 5

1

2

High-throughput

0.515

High

344379

Q8TAS3
PRRG2 protein

1

11

High-throughput

0.515

High

344385

EI2BD
Translation initiation factor eIF2B subunit delta

1

1

High-throughput

0.515

High

344371

GRB2
Growth factor receptor-bound protein 2

1

10

High-throughput

0.508

High

274890

RENR
Renin receptor

1

7

Small-scale

0.501

High

344358

HS90A
Heat shock protein HSP 90-alpha

1

4

Small-scale

0.501

High

344359

NEP
Neprilysin

1

2

Small-scale

0.501

High

344366

PCP
Lysosomal Pro-X carboxypeptidase

1

6

Small-scale

0.501

High

344367

ECE1
Endothelin-converting enzyme 1

1

2

Small-scale

0.501

High

344372

EWS
RNA-binding protein EWS

1

5

High-throughput

0.494

High

344376

SLN12
Ribonuclease SLFN12

1

0

High-throughput

0.493

High

344373

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

7

High-throughput

0.489

High

344375

CIR1
Corepressor interacting with RBPJ 1

1

2

High-throughput

0.489

High

344386

PHF11
PHD finger protein 11

1

9

High-throughput

0.489

High

344357

P53
Cellular tumor antigen p53

1

4

Small-scale

0.481

High

344384

ITSN2
Intersectin-2

1

6

High-throughput

0.481

High

344387

LCAP
Leucyl-cystinyl aminopeptidase

1

0

Small-scale

0.480

High

344363

AGTR1
Type-1 angiotensin II receptor

1

12

Small-scale

0.479

High

344364

STAT3
Signal transducer and activator of transcription 3

1

1

Small-scale

0.479

High

344365

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

Small-scale

0.479

High

344368

SOX2
Transcription factor SOX-2

1

12

High-throughput

0.479

High

344377

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

1

High-throughput

0.470

High

344388

SNX12
Sorting nexin-12

1

1

High-throughput

0.470

High

344370

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.445

High

344380

GSDMB
Gasdermin-B

1

1

High-throughput

0.439

High

344374

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

344381

Q96T11
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to ANKYRIN R

1

9

High-throughput

0.407

High

306379

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

2

0

High-throughput

0.328

High

87234

C9J082
Nephrocystin 1

1

0

High-throughput

0.268

Low

135556

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.268

Low

344378

T185A
Transmembrane protein 185A

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024