Protein: TOP2
DNA topoisomerase 2 top-2 (EC 5.6.2.2) (DNA topoisomerase II)

Gene: TOP2, top-2
Organism: Caenorhabditis elegans
Interactions: 13
UniProt ID: Q23670

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000712 - resolution of meiotic recombination intermediates
GO:0000819 - sister chromatid segregation
GO:0003677 - DNA binding
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

185123

BLM
RecQ-like DNA helicase blm-1

3

1

High-throughput

0.847

High

784747

SSP1A
FACT complex subunit SSRP1-A

2

6

Small-scale

0.584

High

1094561

PFD5
Probable prefoldin subunit 5

2

0

High-throughput

0.551

High

1095094

TPM1
Tropomyosin isoforms a/b/d/f

2

0

High-throughput

0.551

High

185023

RN113
Probable E3 ubiquitin-protein ligase rnf113

1

1

High-throughput

0.541

High

873629

LIN2
Protein lin-2

1

1

High-throughput

0.541

High

219107

O44490
ELKS/RAB6-interacting/CAST family member 2

2

2

High-throughput

0.533

High

136712

SSP1B
FACT complex subunit ssrp1-B

1

7

Small-scale

0.479

High

1095449

Q9TXM1
Uncharacterized protein

1

0

High-throughput

0.458

High

87670

D0IMZ6
FiLamiN

1

1

High-throughput

0.439

High

1094583

PSF1
Probable DNA replication complex GINS protein PSF1

1

1

Small-scale

0.437

High

712143

YMX1
Uncharacterized protein K06H7.1

2

0

High-throughput

0.300

High

91964

E9P875
Neurexin-3-beta

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024