Protein: MBK1
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1 (EC 2.7.12.1) (Dual specificity Yak1-related kinase mbk-1) (Minibrain Kinase 1)

Gene: MBK1, mbk-1
Organism: Caenorhabditis elegans
Interactions: 129
UniProt ID: Q8WQL7

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004712 - protein serine/threonine/tyrosine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

105097

G5ECD7
cGMP-dependent protein kinase interacting domain-containing protein

1

6

High-throughput

0.618

High

106145

G5EDL3
Aurora kinase

1

19

High-throughput

0.618

High

764323

MPK1
Mitogen-activated protein kinase mpk-1

1

16

High-throughput

0.618

High

946379

CDC14
Tyrosine-protein phosphatase cdc-14

1

13

High-throughput

0.618

High

1259289

Q95XK4
PPM-type phosphatase domain-containing protein

1

5

High-throughput

0.618

High

1259299

PAR6
Partitioning defective protein 6

1

1

High-throughput

0.618

High

1259305

GSK3
Glycogen synthase kinase-3

1

20

High-throughput

0.618

High

1259310

SPTF3
Specificity protein transcription factor 3

1

5

High-throughput

0.618

High

1259272

RGS7
Regulator of G-protein signaling rgs-7

1

2

High-throughput

0.553

High

1259292

Q965N4
Chimerin 2

1

7

High-throughput

0.553

High

954253

P91050
Ubiquitin-like domain-containing protein

1

0

High-throughput

0.517

High

104647

G5EC14
Enhancer of polycomb-like protein

1

2

High-throughput

0.479

High

105070

G5ECC0
Kinesin like protein

1

8

High-throughput

0.479

High

106304

LIN35
Retinoblastoma-like protein homolog lin-35

1

14

High-throughput

0.479

High

107242

G5EF11
E2F/DP family winged-helix DNA-binding domain-containing protein

1

11

High-throughput

0.479

High

108158

EGL18
Putative transcription factor egl-18

1

7

High-throughput

0.479

High

110104

H2L033
HAT C-terminal dimerisation domain-containing protein

1

5

High-throughput

0.479

High

137034

O01918
MYND-type domain-containing protein

1

2

High-throughput

0.479

High

184371

GLD2
Poly(A) RNA polymerase gld-2

1

3

High-throughput

0.479

High

184872

PYC1
Pyruvate carboxylase 1

1

3

High-throughput

0.479

High

185144

O18056
RNA helicase

1

16

High-throughput

0.479

High

185209

2A51
Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1

1

3

High-throughput

0.479

High

219965

O45246
Heat shock protein 70

1

11

High-throughput

0.479

High

220062

O45494
C2H2-type domain-containing protein

1

2

High-throughput

0.479

High

220346

NHR49
Nuclear hormone receptor family member nhr-49

1

13

High-throughput

0.479

High

247859

ERGO1
Piwi-like protein ergo-1

1

2

High-throughput

0.479

High

697547

CLAS2
Protein CLASP-2

1

5

High-throughput

0.479

High

711814

KLE2
Condensin-2 complex subunit kle-2

1

1

High-throughput

0.479

High

712077

TBG
Tubulin gamma chain

1

15

High-throughput

0.479

High

712271

CBP1
Protein cbp-1

1

20

High-throughput

0.479

High

953710

P90731
ATP-citrate synthase

1

3

High-throughput

0.479

High

954443

P91400
Kinesin motor domain-containing protein

1

10

High-throughput

0.479

High

1014719

LIN13
Zinc finger protein lin-13

1

3

High-throughput

0.479

High

1088881

CUL3
Cullin-3

1

14

High-throughput

0.479

High

1090850

SCC3
Cohesin subunit scc-3

1

1

High-throughput

0.479

High

1093835

Q20644
RNA helicase

1

8

High-throughput

0.479

High

1094134

APR1
Adenomatous polyposis coli protein-related protein 1

1

1

High-throughput

0.479

High

1094201

NFIL3
Transcription factor atf-2

1

2

High-throughput

0.479

High

1094266

Q21501
YEATS domain-containing protein 4

1

3

High-throughput

0.479

High

1094526

NUF2
Kinetochore protein Nuf2 homolog

1

10

High-throughput

0.479

High

1094550

NAA25
N-terminal acetyltransferase B complex subunit NAA25 homolog

1

1

High-throughput

0.479

High

1094936

Q22590
Protein ECT2

1

9

High-throughput

0.479

High

1094988

TFDP1
Transcription factor dpl-1

1

7

High-throughput

0.479

High

1095007

Q22743
GTP-binding protein

1

7

High-throughput

0.479

High

1095208

Q23138
NET domain-containing protein

1

3

High-throughput

0.479

High

1099772

LI15B
Protein lin-15B

1

4

High-throughput

0.479

High

1122569

Q565A8
SUZ domain-containing protein

1

1

High-throughput

0.479

High

1259285

Q93759
WD_REPEATS_REGION domain-containing protein

1

20

High-throughput

0.479

High

1259295

RUVB2
RuvB-like 2

1

3

High-throughput

0.479

High

1259297

Q9N3F4
RNA helicase

1

10

High-throughput

0.479

High

1259300

SSL1
Helicase ssl-1

1

4

High-throughput

0.479

High

1259302

TIP60
Histone acetyltransferase Tip60 homolog

1

4

High-throughput

0.479

High

1259307

Q9U3F2
DNA replication ATP-dependent helicase/nuclease

1

8

High-throughput

0.479

High

1259311

PP4C1
Serine/threonine-protein phosphatase 4 catalytic subunit 1

1

19

High-throughput

0.479

High

88110

D3NQC0
C2H2-type domain-containing protein

1

0

High-throughput

0.458

High

136767

SBNO
Protein strawberry notch homolog

1

0

High-throughput

0.458

High

1099737

LIN26
Transcription factor lin-26

1

0

High-throughput

0.458

High

1099742

LI15A
Protein lin-15A

1

0

High-throughput

0.458

High

1125980

NFI1
Nuclear factor I family protein

1

0

High-throughput

0.458

High

1228699

Q8MNW1
RNA-binding protein 5

1

0

High-throughput

0.458

High

1259284

Q93230
Vacuolar protein sorting-associated protein 72 homolog

1

0

High-throughput

0.458

High

1259306

DCN1
Defective in cullin neddylation protein 1

1

0

High-throughput

0.458

High

110566

H2L2C8
Alpha-actinin, sarcomeric

1

9

High-throughput

0.439

High

103460

G4SF97
E3 ubiquitin-protein ligase TRIP12

1

14

High-throughput

0.437

High

104436

G5EBS9
Rab-GAP TBC domain-containing protein

1

6

High-throughput

0.437

High

109517

H2KYI3
WAPL domain-containing protein

1

4

High-throughput

0.437

High

109659

H2KZ07
C-type lectin domain-containing protein

1

2

High-throughput

0.437

High

136553

O01585
Rho-GAP domain-containing protein

1

9

High-throughput

0.437

High

137101

O01976
Enhanced RNAI

1

8

High-throughput

0.437

High

183884

O16393
BZIP domain-containing protein

1

3

High-throughput

0.437

High

183902

O16454
Cathepsin F

1

2

High-throughput

0.437

High

218190

O44191
EGF-like domain-containing protein

1

9

High-throughput

0.437

High

247756

O61770
CABIT domain-containing protein

1

1

High-throughput

0.437

High

247918

O62055
EGF-like domain-containing protein

1

10

High-throughput

0.437

High

675349

LIN9
Protein lin-9

1

2

High-throughput

0.437

High

711195

ECHH
Probable 3-ketoacyl-CoA thiolase

1

6

High-throughput

0.437

High

712406

SOR1
Sop-2-related protein 1

1

1

High-throughput

0.437

High

788144

CED3
Cell death protein 3

1

6

High-throughput

0.437

High

1088780

PAR3
Partitioning defective protein 3

1

9

High-throughput

0.437

High

1090505

Q19130
glutamine--fructose-6-phosphate transaminase

1

1

High-throughput

0.437

High

1090920

Q19752
Protein farnesyltransferase subunit beta

1

1

High-throughput

0.437

High

1093776

CNEP1
CTD nuclear envelope phosphatase 1 homolog

1

4

High-throughput

0.437

High

1093840

Q20652
PID domain-containing protein

1

4

High-throughput

0.437

High

1094943

Q22601
AP-2 complex subunit alpha

1

7

High-throughput

0.437

High

1099921

PIMT
Protein-L-isoaspartate O-methyltransferase

1

3

High-throughput

0.437

High

1103694

Q304D5
Thioredoxin domain-containing protein

1

5

High-throughput

0.437

High

1125701

Q5FC73
Uncharacterized protein

1

3

High-throughput

0.437

High

1150009

NU301
Nucleosome-remodeling factor subunit NURF301-like

1

20

High-throughput

0.437

High

1187227

Q7YTG9
Cleavage and polyadenylation specificity factor subunit 4

1

2

High-throughput

0.437

High

1215783

Q8ITV6
FHA domain-containing protein

1

3

High-throughput

0.437

High

1229389

Q8MYM6
REPS

1

11

High-throughput

0.437

High

1259290

Q95XR0
protein-synthesizing GTPase

1

9

High-throughput

0.437

High

1259291

GLD3
Defective in germ line development protein 3

1

2

High-throughput

0.437

High

1259294

Q965V4
Exportin-2

1

7

High-throughput

0.437

High

1259298

Q9N592
U4/U6 small nuclear ribonucleoprotein Prp31

1

2

High-throughput

0.437

High

1259301

Q9TXM1
Uncharacterized protein

1

2

High-throughput

0.437

High

1259303

Q9TZK8
J domain-containing protein

1

2

High-throughput

0.437

High

1259304

Q9U2C2
Protein MCM10 homolog

1

1

High-throughput

0.437

High

1259308

MEX5
Zinc finger protein mex-5

1

7

High-throughput

0.437

High

1259312

Q9XWJ8
Inhibitor of growth protein

1

1

High-throughput

0.437

High

1259313

PLBL1
Putative phospholipase B-like 1

1

1

High-throughput

0.437

High

1095223

Q23158
Alpha-actinin, sarcomeric

1

6

High-throughput

0.417

High

1180460

Q7K7J0
GEX Interacting protein

1

0

High-throughput

0.282

High

816761

ACH2
Acetylcholine receptor subunit beta-type unc-29

1

0

High-throughput

0.269

Low

107127

G5EEQ7
SH3 domain-containing protein

1

0

High-throughput

0.251

Low

90277

D9PTP8
Sorting nexin/Vps5-like C-terminal domain-containing protein

1

0

High-throughput

0.249

Low

104539

G5EBW5
FErroChelatase-Like

1

0

High-throughput

0.249

Low

109330

H2KML5
RING-type E3 ubiquitin transferase

1

0

High-throughput

0.249

Low

109770

H2KZ79
Ig-like domain-containing protein

1

0

High-throughput

0.249

Low

185199

O18167
INTegrator complex Subunit homolog

1

0

High-throughput

0.249

Low

247559

O61522
TransThyretin-Related family domain

1

0

High-throughput

0.249

Low

248063

DCP2
m7GpppN-mRNA hydrolase dcap-2

1

0

High-throughput

0.249

Low

711982

RETR1
Retrotransposon-like protein 1

1

0

High-throughput

0.249

Low

712369

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.249

Low

954797

SPD2
Spindle-defective protein 2

1

0

High-throughput

0.249

Low

1001251

Q0G832
JAKMIP_CC3 domain-containing protein

1

0

High-throughput

0.249

Low

1090598

Q19276
Ferritin

1

0

High-throughput

0.249

Low

1090951

Q19816
Calponin-homology

1

0

High-throughput

0.249

Low

1090964

RPAB3
Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.249

Low

1094182

LET99
Protein let-99

1

0

High-throughput

0.249

Low

1094284

Q21504
FAD-dependent oxidoreductase domain-containing protein 1

1

0

High-throughput

0.249

Low

1094906

Q22500
Transthyretin-like family protein

1

0

High-throughput

0.249

Low

1259286

Q94314
Flocculation protein FLO11-like

1

0

High-throughput

0.249

Low

1259287

Q95Q05
MITD1 C-terminal phospholipase D-like domain-containing protein

1

0

High-throughput

0.249

Low

1259288

Q95XJ5
Cilia- and flagella-associated protein 157

1

0

High-throughput

0.249

Low

1259293

Q965Q6
Drf_GBD domain-containing protein

1

0

High-throughput

0.249

Low

1259296

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.249

Low

1259309

Q9XUU5
Armadillo repeat-containing protein 1

1

0

High-throughput

0.249

Low

1259314

ACKMT
ATP synthase subunit C lysine N-methyltransferase

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024