Protein: PRKN
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)

Gene: PRKN
Organism: Rattus norvegicus
Interactions: 14
UniProt ID: Q9JK66

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0000266 - mitochondrial fission

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1337501

PRKN
E3 ubiquitin-protein ligase parkin

4

17

Small-scale

0.888

High

1144074

CSKP
Peripheral plasma membrane protein CASK

1

13

Small-scale

0.665

High

88504

D3Z8W5
E2 ubiquitin-conjugating enzyme

1

20

Small-scale

0.647

High

88856

D4A054
RAN binding protein 2

1

7

Small-scale

0.618

High

974746

CDK5
Cyclin-dependent kinase 5

1

11

Small-scale

0.618

High

1144287

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]

1

19

Small-scale

0.618

High

1337502

TRIB3
Tribbles homolog 3

1

13

Small-scale

0.618

High

621442

SC6A3
Sodium-dependent dopamine transporter

1

4

Small-scale

0.561

High

193558

AFAD
Afadin

1

11

Small-scale

0.479

High

653427

CAC1D
Voltage-dependent L-type calcium channel subunit alpha-1D

1

1

Small-scale

0.479

High

663948

ARRB1
Beta-arrestin-1

1

9

Small-scale

0.479

High

838410

SYT4
Synaptotagmin-4

1

4

Small-scale

0.479

High

1265171

BECN1
Beclin-1

1

3

Small-scale

0.479

High


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Last updated: 15 Jul 2024