Protein: TRIM8
E3 ubiquitin-protein ligase TRIM8 (EC 2.3.2.27) (Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8)

Gene: TRIM8
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q9BZR9

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007249 - canonical NF-kappaB signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

159090

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

3

20

High-throughput

0.861

High

849436

UB2D1
Ubiquitin-conjugating enzyme E2 D1

3

20

High-throughput

0.861

High

1318358

UB2D4
Ubiquitin-conjugating enzyme E2 D4

3

20

High-throughput

0.861

High

1318343

TRIM8
E3 ubiquitin-protein ligase TRIM8

3

19

Small-scale

0.858

High

919850

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

20

Small-scale

0.800

High

872209

RD23A
UV excision repair protein RAD23 homolog A

2

20

High-throughput

0.783

High

170468

TIF1A
Transcription intermediary factor 1-alpha

1

18

High-throughput

0.698

High

585056

RO52
E3 ubiquitin-protein ligase TRIM21

1

18

High-throughput

0.698

High

895902

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

High-throughput

0.698

High

1033140

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

20

High-throughput

0.698

High

1052763

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

19

High-throughput

0.698

High

1284881

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.698

High

1297109

TRI47
E3 ubiquitin-protein ligase TRIM47

1

19

High-throughput

0.698

High

1299584

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

9

High-throughput

0.698

High

1318344

TRI15
E3 ubiquitin-protein ligase TRIM15

1

20

High-throughput

0.698

High

1318345

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

20

High-throughput

0.698

High

1318346

TRIM2
Tripartite motif-containing protein 2

1

19

High-throughput

0.698

High

1318352

TRI39
E3 ubiquitin-protein ligase TRIM39

1

20

High-throughput

0.698

High

201425

M3K7
Mitogen-activated protein kinase kinase kinase 7

4

11

Small-scale

0.692

High

1288092

OTUB2
Ubiquitin thioesterase OTUB2

3

15

High-throughput

0.654

High

1296353

TNIP3
TNFAIP3-interacting protein 3

3

12

Small-scale

0.653

High

307212

KLHL2
Kelch-like protein 2

2

8

High-throughput

0.611

High

155633

TNPO2
Transportin-2

2

6

High-throughput

0.606

High

299466

UBXN7
UBX domain-containing protein 7

2

6

High-throughput

0.606

High

800626

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

2

20

High-throughput

0.606

High

830013

HXA1
Homeobox protein Hox-A1

2

20

High-throughput

0.606

High

883385

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

15

High-throughput

0.606

High

1089378

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

17

High-throughput

0.606

High

1138859

OTU1
Ubiquitin thioesterase OTU1

2

3

High-throughput

0.606

High

1144617

TENS2
Tensin-2

2

6

High-throughput

0.606

High

1223726

RN168
E3 ubiquitin-protein ligase RNF168

2

3

High-throughput

0.606

High

1232311

MTURN
Maturin

2

3

High-throughput

0.606

High

1252462

LNX1
E3 ubiquitin-protein ligase LNX

2

12

High-throughput

0.606

High

1292385

DCNL1
DCN1-like protein 1

2

2

High-throughput

0.606

High

537045

TRI27
Zinc finger protein RFP

1

18

Small-scale

0.590

High

1273855

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

13

High-throughput

0.584

High

1244918

NUD10
Diphosphoinositol polyphosphate phosphohydrolase 3-alpha

2

0

High-throughput

0.580

High

370380

ESR1
Estrogen receptor

1

20

Small-scale

0.578

High

438499

HS90B
Heat shock protein HSP 90-beta

1

20

Small-scale

0.561

High

1216102

TCAM1
TIR domain-containing adapter molecule 1

1

3

Small-scale

0.561

High

1243109

CTSR1
Cation channel sperm-associated protein 1

2

9

High-throughput

0.553

High

1318348

F124B
Protein FAM124B

2

4

High-throughput

0.553

High

129595

TRAF5
TNF receptor-associated factor 5

1

20

High-throughput

0.541

High

182893

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.541

High

610502

CBL
E3 ubiquitin-protein ligase CBL

1

9

High-throughput

0.541

High

819668

NRIP1
Nuclear receptor-interacting protein 1

1

1

High-throughput

0.541

High

957775

XIAP
E3 ubiquitin-protein ligase XIAP

1

5

High-throughput

0.541

High

1023553

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

5

High-throughput

0.541

High

1169187

RN111
E3 ubiquitin-protein ligase Arkadia

1

4

High-throughput

0.541

High

1190828

BRAP
BRCA1-associated protein

1

20

High-throughput

0.541

High

1197589

PCGF5
Polycomb group RING finger protein 5

1

19

High-throughput

0.541

High

1216702

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

13

High-throughput

0.541

High

1261298

RN138
E3 ubiquitin-protein ligase RNF138

1

19

High-throughput

0.541

High

1285825

TRI43
Tripartite motif-containing protein 43

1

18

High-throughput

0.541

High

1318347

RNF41
E3 ubiquitin-protein ligase NRDP1

1

20

High-throughput

0.541

High

1318349

RC3H2
Roquin-2

1

11

High-throughput

0.541

High

1318353

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.541

High

1318354

RN181
E3 ubiquitin-protein ligase RNF181

1

6

High-throughput

0.541

High

1318356

RBX2
RING-box protein 2

1

4

High-throughput

0.541

High

535924

MIF
Macrophage migration inhibitory factor

1

2

High-throughput

0.536

High

1183390

RUFY3
Protein RUFY3

1

11

High-throughput

0.536

High

1299468

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.518

High

1318351

MSL2
E3 ubiquitin-protein ligase MSL2

1

0

High-throughput

0.518

High

1025952

TADBP
TAR DNA-binding protein 43

1

20

High-throughput

0.515

High

724463

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

High-throughput

0.513

High

1074570

CDSN
Corneodesmosin

1

0

High-throughput

0.513

High

1261319

RN141
RING finger protein 141

1

7

High-throughput

0.494

High

271187

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

20

High-throughput

0.481

High

599725

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

12

High-throughput

0.481

High

851224

CCNH
Cyclin-H

1

5

High-throughput

0.481

High

1078905

ITSN1
Intersectin-1

1

4

High-throughput

0.481

High

1121194

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

20

High-throughput

0.481

High

1318355

MAGC2
Melanoma-associated antigen C2

1

20

Small-scale

0.481

High

1318357

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

20

High-throughput

0.481

High

181891

SOCS1
Suppressor of cytokine signaling 1

1

15

Small-scale

0.479

High

318719

EYA4
Eyes absent homolog 4

1

7

High-throughput

0.479

High

377659

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

387455

P53
Cellular tumor antigen p53

1

13

Small-scale

0.479

High

422636

GPX1
Glutathione peroxidase 1

1

2

Small-scale

0.479

High

507502

ERG
Transcriptional regulator ERG

1

12

Small-scale

0.479

High

639799

IKBA
NF-kappa-B inhibitor alpha

1

15

Small-scale

0.479

High

795665

MAGA1
Melanoma-associated antigen 1

1

20

Small-scale

0.479

High

855728

KIF11
Kinesin-like protein KIF11

1

18

Small-scale

0.479

High

967411

EWS
RNA-binding protein EWS

1

11

Small-scale

0.479

High

1023231

FLII
Protein flightless-1 homolog

1

2

Small-scale

0.479

High

1042477

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1314331

KIFC1
Kinesin-like protein KIFC1

1

18

Small-scale

0.479

High

1318360

PIAS3
E3 SUMO-protein ligase PIAS3

1

15

Small-scale

0.479

High

989102

FMR1
Fragile X messenger ribonucleoprotein 1

1

12

High-throughput

0.457

High

1318350

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

18

Small-scale

0.457

High

1318359

CD2AP
CD2-associated protein

1

10

High-throughput

0.457

High

89983

D6R9G5
Kelch like family member 2

1

14

High-throughput

0.407

High


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Last updated: 15 Jul 2024