Protein: DBLOH
Diablo IAP-binding mitochondrial protein (Diablo homolog, mitochondrial) (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) [Cleaved into: Diablo IAP-binding mitochondrial protein, cleaved form]

Gene: DBLOH, DIABLO
Organism: Homo sapiens
Interactions: 230
UniProt ID: Q9NR28

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0006919 - activation of cysteine-type endopeptidase activity involved in apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

957787

XIAP
E3 ubiquitin-protein ligase XIAP

52

11

Small-scale

0.996

High

1344002

BIRC6
Baculoviral IAP repeat-containing protein 6

14

9

Small-scale

0.988

High

1036359

BIRC2
Baculoviral IAP repeat-containing protein 2

18

11

Small-scale

0.988

High

1036115

BIRC3
Baculoviral IAP repeat-containing protein 3

10

11

Small-scale

0.974

High

1286581

BIRC7
Baculoviral IAP repeat-containing protein 7

8

11

Small-scale

0.973

High

177726

BIRC5
Baculoviral IAP repeat-containing protein 5

6

11

Small-scale

0.953

High

1298966

BIRC8
Baculoviral IAP repeat-containing protein 8

4

11

Small-scale

0.892

High

1344085

DBLOH
Diablo IAP-binding mitochondrial protein

5

0

Small-scale

0.863

High

1020948

TRAF2
TNF receptor-associated factor 2

5

4

High-throughput

0.720

High

1072887

MTFR1
Mitochondrial fission regulator 1

5

1

High-throughput

0.717

High

1023812

TRAF1
TNF receptor-associated factor 1

4

3

Small-scale

0.697

High

1065330

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

4

0

High-throughput

0.675

High

1291301

DYL2
Dynein light chain 2, cytoplasmic

3

1

High-throughput

0.667

High

1305281

PHB2
Prohibitin-2

3

1

High-throughput

0.656

High

896382

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

1

Small-scale

0.629

High

928480

DYL1
Dynein light chain 1, cytoplasmic

2

1

High-throughput

0.628

High

204063

HTRA2
Serine protease HTRA2, mitochondrial

2

1

Small-scale

0.624

High

738703

TNR3
Tumor necrosis factor receptor superfamily member 3

2

1

Small-scale

0.621

High

1023642

BIRC1
Baculoviral IAP repeat-containing protein 1

1

11

Small-scale

0.618

High

1191208

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

1

High-throughput

0.606

High

878618

ALR
FAD-linked sulfhydryl oxidase ALR

2

0

High-throughput

0.602

High

1344087

DUS22
Dual specificity protein phosphatase 22

2

0

High-throughput

0.602

High

307219

KLHL2
Kelch-like protein 2

2

0

High-throughput

0.585

High

325415

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

1

High-throughput

0.584

High

719174

PHB1
Prohibitin 1

2

1

High-throughput

0.584

High

1344110

TRAF6
TNF receptor-associated factor 6

2

4

Small-scale

0.584

High

316451

MPC2
Mitochondrial pyruvate carrier 2

2

0

High-throughput

0.580

High

1140503

MIC13
MICOS complex subunit MIC13

2

0

High-throughput

0.580

High

1231824

S66A2
Solute carrier family 66 member 2

2

0

High-throughput

0.580

High

1297574

RMD2
Regulator of microtubule dynamics protein 2

2

0

High-throughput

0.580

High

1342977

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.580

High

476432

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

0

Small-scale

0.569

High

1156132

RHBD2
Rhomboid domain-containing protein 2

2

1

High-throughput

0.553

High

1294717

SC22A
Vesicle-trafficking protein SEC22a

2

1

High-throughput

0.553

High

165293

AREL1
Apoptosis-resistant E3 ubiquitin protein ligase 1

1

0

Small-scale

0.537

High

949063

HTRA4
Serine protease HTRA4

1

1

High-throughput

0.536

High

1268598

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

1

High-throughput

0.536

High

1344106

MKLN1
Muskelin

1

1

High-throughput

0.536

High

452892

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

636523

DNJB2
DnaJ homolog subfamily B member 2

1

0

High-throughput

0.513

High

739410

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

0

High-throughput

0.513

High

905154

1433G
14-3-3 protein gamma

1

0

High-throughput

0.513

High

1216842

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.513

High

1271765

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1327585

TOLIP
Toll-interacting protein

1

0

High-throughput

0.513

High

1344103

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.513

High

1344104

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.513

High

1024768

TRAF3
TNF receptor-associated factor 3

1

4

Small-scale

0.506

High

828028

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

Small-scale

0.501

High

207274

TNF14
Tumor necrosis factor ligand superfamily member 14

1

0

Small-scale

0.493

High

984536

KPCD
Protein kinase C delta type

1

0

Small-scale

0.493

High

1273581

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

0

High-throughput

0.493

High

995594

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.493

High

932886

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.486

High

1156399

ZN746
Zinc finger protein 746

1

0

High-throughput

0.486

High

1163061

S2547
Solute carrier family 25 member 47

1

1

High-throughput

0.481

High

864876

MK10
Mitogen-activated protein kinase 10

1

0

Small-scale

0.480

High

895924

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

0

Small-scale

0.480

High

180938

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.479

High

224663

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

2

High-throughput

0.479

High

264640

MTX2
Metaxin-2

1

2

High-throughput

0.479

High

274641

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

1

High-throughput

0.479

High

325904

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.479

High

509736

UBL4A
Ubiquitin-like protein 4A

1

1

High-throughput

0.479

High

639650

TNR5
Tumor necrosis factor receptor superfamily member 5

1

1

Small-scale

0.479

High

909180

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

994811

GOGA3
Golgin subfamily A member 3

1

1

High-throughput

0.479

High

1135346

ATD3B
ATPase family AAA domain-containing protein 3B

1

1

High-throughput

0.479

High

1159101

CEP85
Centrosomal protein of 85 kDa

1

1

High-throughput

0.479

High

1159601

MTFR2
Mitochondrial fission regulator 2

1

1

High-throughput

0.479

High

1223682

MICU2
Calcium uptake protein 2, mitochondrial

1

2

High-throughput

0.479

High

1230726

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

1

High-throughput

0.479

High

1240316

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1293054

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.479

High

1303114

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

1

High-throughput

0.479

High

1308655

MICU1
Calcium uptake protein 1, mitochondrial

1

2

High-throughput

0.479

High

1310405

MIC25
MICOS complex subunit MIC25

1

1

High-throughput

0.479

High

1317805

NUF2
Kinetochore protein Nuf2

1

2

High-throughput

0.479

High

1331805

RNF41
E3 ubiquitin-protein ligase NRDP1

1

2

Small-scale

0.479

High

1335667

TPC
Mitochondrial thiamine pyrophosphate carrier

1

1

High-throughput

0.479

High

1344092

DJC11
DnaJ homolog subfamily C member 11

1

1

High-throughput

0.479

High

1344093

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.479

High

1344095

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.479

High

1344111

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.479

High

1344113

TIM8B
Mitochondrial import inner membrane translocase subunit Tim8 B

1

2

High-throughput

0.479

High

1344114

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

2

High-throughput

0.479

High

611513

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

0

High-throughput

0.460

High

118468

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

121380

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

1

0

High-throughput

0.458

High

160797

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

201446

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.458

High

215487

SCO2
Protein SCO2 homolog, mitochondrial

1

0

High-throughput

0.458

High

217607

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.458

High

231164

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.458

High

237325

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

262986

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

266830

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

297105

TOM70
Mitochondrial import receptor subunit TOM70

1

0

High-throughput

0.458

High

320423

SNP29
Synaptosomal-associated protein 29

1

0

High-throughput

0.458

High

330735

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.458

High

335319

DYR
Dihydrofolate reductase

1

0

High-throughput

0.458

High

335873

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.458

High

519829

KCRU
Creatine kinase U-type, mitochondrial

1

0

High-throughput

0.458

High

525652

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

540764

CX6B1
Cytochrome c oxidase subunit 6B1

1

0

High-throughput

0.458

High

583370

HXK1
Hexokinase-1

1

0

High-throughput

0.458

High

658174

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.458

High

736193

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

1

0

High-throughput

0.458

High

739309

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.458

High

795053

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

808956

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

851978

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

1

0

High-throughput

0.458

High

868342

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

878749

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

0

High-throughput

0.458

High

896981

ARP2
Actin-related protein 2

1

0

High-throughput

0.458

High

949177

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

960335

CDK5
Cyclin-dependent kinase 5

1

0

High-throughput

0.458

High

997642

DMPK
Myotonin-protein kinase

1

0

High-throughput

0.458

High

1014519

MPPA
Mitochondrial-processing peptidase subunit alpha

1

0

High-throughput

0.458

High

1022669

AF1Q
Protein AF1q

1

0

High-throughput

0.458

High

1034629

GOGA4
Golgin subfamily A member 4

1

0

High-throughput

0.458

High

1042620

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1052388

NUCG
Endonuclease G, mitochondrial

1

0

High-throughput

0.458

High

1061630

CUL7
Cullin-7

1

0

High-throughput

0.458

High

1063127

ABRX2
BRISC complex subunit Abraxas 2

1

0

High-throughput

0.458

High

1067477

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

1077965

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.458

High

1088663

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

1150496

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

1

0

High-throughput

0.458

High

1166791

MIC27
MICOS complex subunit MIC27

1

0

High-throughput

0.458

High

1183233

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1184053

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.458

High

1190102

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.458

High

1191384

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

1

0

High-throughput

0.458

High

1220674

MIRO2
Mitochondrial Rho GTPase 2

1

0

High-throughput

0.458

High

1232213

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

0

High-throughput

0.458

High

1233635

TOM5
Mitochondrial import receptor subunit TOM5 homolog

1

0

High-throughput

0.458

High

1233806

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.458

High

1241427

MTMRE
Myotubularin-related protein 14

1

0

High-throughput

0.458

High

1245199

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1252130

PUM2
Pumilio homolog 2

1

0

High-throughput

0.458

High

1268801

RT31
Small ribosomal subunit protein mS31

1

0

High-throughput

0.458

High

1285030

TOM6
Mitochondrial import receptor subunit TOM6 homolog

1

0

High-throughput

0.458

High

1285870

COA7
Cytochrome c oxidase assembly factor 7

1

0

High-throughput

0.458

High

1290643

PTCD3
Small ribosomal subunit protein mS39

1

0

High-throughput

0.458

High

1293824

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

High-throughput

0.458

High

1296918

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1297472

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.458

High

1326930

NAA50
N-alpha-acetyltransferase 50

1

0

High-throughput

0.458

High

1327248

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.458

High

1334158

SFXN1
Sideroflexin-1

1

0

High-throughput

0.458

High

1334401

CSN7B
COP9 signalosome complex subunit 7b

1

0

High-throughput

0.458

High

1344088

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.458

High

1344089

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1344090

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.458

High

1344091

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1344096

ITSN2
Intersectin-2

1

0

High-throughput

0.458

High

1344097

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.458

High

1344099

ATX10
Ataxin-10

1

0

High-throughput

0.458

High

1344101

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

0

Small-scale

0.458

High

1344102

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1344105

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.458

High

1344107

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.458

High

1344108

TMX2
Thioredoxin-related transmembrane protein 2

1

0

High-throughput

0.458

High

1344109

RT02
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.458

High

1344112

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.458

High

279727

FLOT1
Flotillin-1

1

1

High-throughput

0.437

High

885615

MLF1
Myeloid leukemia factor 1

1

1

High-throughput

0.437

High

1037160

MTX1
Metaxin-1

1

2

High-throughput

0.437

High

1078360

MLF2
Myeloid leukemia factor 2

1

1

High-throughput

0.437

High

1126185

MTX3
Metaxin-3

1

2

High-throughput

0.437

High

497643

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

89988

D6R9G5
Kelch like family member 2

1

1

High-throughput

0.407

High

963688

E2F1
Transcription factor E2F1

1

0

Small-scale

0.391

High

1164273

ATRAP
Type-1 angiotensin II receptor-associated protein

3

0

High-throughput

0.348

High

439183

SYPH
Synaptophysin

2

0

High-throughput

0.316

High

874427

APOC4
Apolipoprotein C-IV

2

0

High-throughput

0.316

High

1169575

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

2

0

High-throughput

0.316

High

1224741

CKLF4
CKLF-like MARVEL transmembrane domain-containing protein 4

2

0

High-throughput

0.316

High

1238384

FADS6
Fatty acid desaturase 6

2

0

High-throughput

0.316

High

1260988

SFT2A
Vesicle transport protein SFT2A

2

0

High-throughput

0.316

High

1297162

DHRS1
Dehydrogenase/reductase SDR family member 1

2

0

High-throughput

0.316

High

1317400

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

2

0

High-throughput

0.316

High

1326102

DERL2
Derlin-2

2

0

High-throughput

0.316

High

1328487

STMN4
Stathmin-4

2

0

High-throughput

0.316

High

1344115

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

0

High-throughput

0.316

High

848572

CAV2
Caveolin-2

2

0

High-throughput

0.298

High

649163

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

0

High-throughput

0.282

High

1224503

MAML2
Mastermind-like protein 2

1

0

High-throughput

0.282

High

449006

GROA
Growth-regulated alpha protein

1

0

High-throughput

0.279

Low

792734

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.279

Low

801408

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.279

Low

1218045

GID4
Glucose-induced degradation protein 4 homolog

1

0

High-throughput

0.279

Low

1334492

RPF1
Ribosome production factor 1

1

0

High-throughput

0.279

Low

648082

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.268

Low

902851

UFM1
Ubiquitin-fold modifier 1

1

0

High-throughput

0.265

Low

1315365

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.261

Low

361679

APOC2
Apolipoprotein C-II

1

0

High-throughput

0.251

Low

1344100

HSFX1
Heat shock transcription factor, X-linked

1

0

High-throughput

0.251

Low

209488

PLRG1
Pleiotropic regulator 1

1

0

High-throughput

0.249

Low

214677

MYO1B
Unconventional myosin-Ib

1

0

High-throughput

0.249

Low

236460

RNBP6
Ran-binding protein 6

1

0

High-throughput

0.249

Low

297200

IPO13
Importin-13

1

0

High-throughput

0.249

Low

330360

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.249

Low

354571

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

594981

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.249

Low

749880

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.249

Low

763107

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.249

Low

789353

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.249

Low

958328

AT2C1
Calcium-transporting ATPase type 2C member 1

1

0

High-throughput

0.249

Low

1054606

RBM39
RNA-binding protein 39

1

0

High-throughput

0.249

Low

1085072

DREB
Drebrin

1

0

High-throughput

0.249

Low

1086501

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

0

High-throughput

0.249

Low

1127321

TGO1
Transport and Golgi organization protein 1 homolog

1

0

High-throughput

0.249

Low

1131021

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.249

Low

1138633

OTUD1
OTU domain-containing protein 1

1

0

Small-scale

0.249

Low

1171862

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1173030

TM1L2
TOM1-like protein 2

1

0

High-throughput

0.249

Low

1174425

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.249

Low

1216997

LRC49
Leucine-rich repeat-containing protein 49

1

0

High-throughput

0.249

Low

1218575

MA7D3
MAP7 domain-containing protein 3

1

0

High-throughput

0.249

Low

1220478

DJC10
DnaJ homolog subfamily C member 10

1

0

High-throughput

0.249

Low

1252215

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1295324

TMX3
Protein disulfide-isomerase TMX3

1

0

High-throughput

0.249

Low

1344086

DPOE4
DNA polymerase epsilon subunit 4

1

0

High-throughput

0.249

Low

1344094

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

1344098

RERE
Arginine-glutamic acid dipeptide repeats protein

1

0

High-throughput

0.249

Low

1103091

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.232

Low

1344116

CCD61
Centrosomal protein CCDC61

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024