Protein: CTSL2
CTD small phosphatase-like protein 2 (CTDSP-like 2) (EC 3.1.3.-)

Gene: CTSL2, CTDSPL2
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q05D32

Gene Ontology (top 5):
GO:0004721 - phosphoprotein phosphatase activity
GO:0005654 - nucleoplasm
GO:0006611 - protein export from nucleus
GO:0008420 - RNA polymerase II CTD heptapeptide repeat phosphatase activity
GO:0030514 - negative regulation of BMP signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

985679

PDK1L
Serine/threonine-protein kinase PDIK1L

6

7

Small-scale

0.736

High

985681

STK35
Serine/threonine-protein kinase 35

4

3

Small-scale

0.699

High

853248

IMA1
Importin subunit alpha-1

3

4

Small-scale

0.667

High

134881

IMA3
Importin subunit alpha-3

3

4

Small-scale

0.651

High

985659

CTSL2
CTD small phosphatase-like protein 2

1

6

Small-scale

0.618

High

131420

IMA4
Importin subunit alpha-4

2

4

Small-scale

0.611

High

853575

IMA5
Importin subunit alpha-5

2

4

Small-scale

0.611

High

985666

IMB1
Importin subunit beta-1

2

1

Small-scale

0.611

High

486896

MYBB
Myb-related protein B

1

1

High-throughput

0.536

High

834587

NU153
Nuclear pore complex protein Nup153

1

5

High-throughput

0.536

High

985671

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

985684

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.536

High

801681

RAGP1
Ran GTPase-activating protein 1

1

0

High-throughput

0.513

High

834722

RBP2
E3 SUMO-protein ligase RanBP2

1

0

High-throughput

0.513

High

985667

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.513

High

616801

JAK1
Tyrosine-protein kinase JAK1

1

5

High-throughput

0.489

High

985673

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

5

High-throughput

0.489

High

985682

SCYL1
N-terminal kinase-like protein

1

3

High-throughput

0.489

High

985686

KLF16
Krueppel-like factor 16

1

13

High-throughput

0.489

High

214226

SPOP
Speckle-type POZ protein

1

1

Small-scale

0.481

High

209912

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.479

High

238661

IMA7
Importin subunit alpha-7

1

4

Small-scale

0.479

High

414883

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.479

High

726763

FUS
RNA-binding protein FUS

1

1

Small-scale

0.479

High

917156

H4
Histone H4

1

1

High-throughput

0.479

High

918308

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

934687

H31
Histone H3.1

1

2

High-throughput

0.479

High

952289

H33
Histone H3.3

1

2

High-throughput

0.479

High

985661

ILF2
Interleukin enhancer-binding factor 2

1

1

Small-scale

0.479

High

985662

ILF3
Interleukin enhancer-binding factor 3

1

1

Small-scale

0.479

High

985670

ELOC
Elongin-C

1

1

High-throughput

0.479

High

985676

NIPBL
Nipped-B-like protein

1

4

Small-scale

0.479

High

985688

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

985690

NCOA3
Nuclear receptor coactivator 3

1

1

Small-scale

0.479

High

202130

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

0

Small-scale

0.458

High

233391

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

455354

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.458

High

652826

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

852885

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

Small-scale

0.458

High

985665

TADBP
TAR DNA-binding protein 43

1

0

Small-scale

0.458

High

985685

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

502007

BIP
Endoplasmic reticulum chaperone BiP

1

2

Small-scale

0.437

High

551678

DESP
Desmoplakin

1

1

Small-scale

0.437

High

649474

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.437

High

880450

ATP5E
ATP synthase subunit epsilon, mitochondrial

1

1

High-throughput

0.437

High

885235

EPIPL
Epiplakin

1

1

Small-scale

0.437

High

950771

ERH
Enhancer of rudimentary homolog

1

1

Small-scale

0.437

High

985664

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

3

High-throughput

0.437

High

985668

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

985669

BRD3
Bromodomain-containing protein 3

1

4

High-throughput

0.437

High

985683

FGD4
FYVE, RhoGEF and PH domain-containing protein 4

1

3

High-throughput

0.437

High

985687

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

91330

E5RHG8
Elongin-C

1

1

High-throughput

0.407

High

101763

F8W7C6
Large ribosomal subunit protein uL16

1

1

High-throughput

0.407

High

985674

AT5EL
ATP synthase subunit epsilon-like protein, mitochondrial

1

1

High-throughput

0.407

High

161519

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.279

Low

985663

MYO1E
Unconventional myosin-Ie

1

0

High-throughput

0.279

Low

985672

PPR29
Protein phosphatase 1 regulatory subunit 29

1

0

High-throughput

0.279

Low

985677

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.279

Low

985678

CPNE8
Copine-8

1

0

High-throughput

0.279

Low

985680

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.279

Low

985689

IPP
Actin-binding protein IPP

1

0

High-throughput

0.279

Low

100699

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

559388

H13
Histone H1.3

1

0

Small-scale

0.249

Low

973036

RL6
Large ribosomal subunit protein eL6

1

0

Small-scale

0.249

Low

985660

NU160
Nuclear pore complex protein Nup160

1

0

Small-scale

0.249

Low

985675

H2A2A
Histone H2A type 2-A

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024