Protein: KDM1B
Lysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B)

Gene: KDM1B
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q8NB78

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000786 - nucleosome
GO:0003682 - chromatin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

934992

H31
Histone H3.1

3

8

Small-scale

0.817

High

1239574

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

6

5

Small-scale

0.730

High

1176246

ASXL2
Putative Polycomb group protein ASXL2

5

5

High-throughput

0.718

High

1087268

H2B2E
Histone H2B type 2-E

1

5

High-throughput

0.691

High

1115548

GLYR1
Cytokine-like nuclear factor N-PAC

3

2

High-throughput

0.667

High

1086222

H31T
Histone H3.1t

1

8

Small-scale

0.647

High

1239570

KDM1B
Lysine-specific histone demethylase 2

1

6

Small-scale

0.647

High

918526

H2B1C
Histone H2B type 1-C/E/F/G/I

1

5

High-throughput

0.618

High

952473

H33
Histone H3.3

1

8

High-throughput

0.618

High

1239580

NSD3
Histone-lysine N-methyltransferase NSD3

2

8

Small-scale

0.611

High

311266

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

3

1

High-throughput

0.609

High

1239582

SH22A
SH2 domain-containing protein 2A

3

3

High-throughput

0.609

High

244669

BRD4
Bromodomain-containing protein 4

2

3

High-throughput

0.584

High

1067052

BRD3
Bromodomain-containing protein 3

2

7

High-throughput

0.584

High

370019

ESR1
Estrogen receptor

2

13

High-throughput

0.571

High

175044

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

Small-scale

0.561

High

172882

CASC3
Protein CASC3

1

6

High-throughput

0.536

High

416659

S10A6
Protein S100-A6

1

1

High-throughput

0.536

High

949847

CBX1
Chromobox protein homolog 1

1

6

High-throughput

0.536

High

1069426

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1218824

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1239585

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

0

High-throughput

0.513

High

427758

CO8B
Complement component C8 beta chain

1

2

High-throughput

0.489

High

1033298

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

5

High-throughput

0.489

High

1151799

ABLM2
Actin-binding LIM protein 2

1

4

High-throughput

0.489

High

895847

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

0

Small-scale

0.480

High

631509

BRD2
Bromodomain-containing protein 2

1

5

High-throughput

0.479

High

632818

TYY1
Transcriptional repressor protein YY1

1

7

High-throughput

0.479

High

692162

ELF1
ETS-related transcription factor Elf-1

1

2

High-throughput

0.479

High

903369

WDR5
WD repeat-containing protein 5

1

4

Small-scale

0.479

High

917604

H4
Histone H4

1

1

High-throughput

0.479

High

964215

FOXK2
Forkhead box protein K2

1

2

High-throughput

0.479

High

1042055

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1056891

MDC1
Mediator of DNA damage checkpoint protein 1

1

2

High-throughput

0.479

High

1057318

SMC1A
Structural maintenance of chromosomes protein 1A

1

2

Small-scale

0.479

High

1173183

PAXI1
PAX-interacting protein 1

1

5

Small-scale

0.479

High

1239571

KMT2C
Histone-lysine N-methyltransferase 2C

1

10

Small-scale

0.479

High

1239575

ESR2
Estrogen receptor beta

1

13

High-throughput

0.479

High

1239577

MBD6
Methyl-CpG-binding domain protein 6

1

6

High-throughput

0.479

High

1239578

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

9

Small-scale

0.479

High

1239584

MBD5
Methyl-CpG-binding domain protein 5

1

1

High-throughput

0.479

High

236802

CCNT1
Cyclin-T1

1

0

Small-scale

0.458

High

1239583

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

91561

E7EWD6
ASXL transcriptional regulator 2

1

6

High-throughput

0.445

High

101753

F8W6N3
Ubiquitin carboxyl-terminal hydrolase

1

5

High-throughput

0.445

High

1239581

Q9HCK3
KIAA1569 protein

1

1

High-throughput

0.437

High

1239573

CE192
Centrosomal protein of 192 kDa

1

1

High-throughput

0.407

High

1239579

SPT17
Spermatogenesis-associated protein 17

3

0

High-throughput

0.342

High

1190908

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

1239572

HAVR2
Hepatitis A virus cellular receptor 2

2

0

High-throughput

0.328

High

594930

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.279

Low

1190548

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

1239576

ANKR9
Ankyrin repeat domain-containing protein 9

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024