Protein: NEST
Nestin

Gene: NEST, NES
Organism: Homo sapiens
Interactions: 142
UniProt ID: P48681

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0005737 - cytoplasm
GO:0005882 - intermediate filament
GO:0007417 - central nervous system development
GO:0007420 - brain development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

443391

VIME
Vimentin

7

20

High-throughput

0.967

High

422365

NFM
Neurofilament medium polypeptide

3

20

High-throughput

0.861

High

535346

GFAP
Glial fibrillary acidic protein

3

19

High-throughput

0.861

High

409029

K2C8
Keratin, type II cytoskeletal 8

2

20

High-throughput

0.776

High

781868

PERI
Peripherin

2

19

High-throughput

0.754

High

166108

SYNEM
Synemin

1

20

High-throughput

0.691

High

422152

NFL
Neurofilament light polypeptide

1

20

High-throughput

0.691

High

444529

K2C7
Keratin, type II cytoskeletal 7

1

20

High-throughput

0.691

High

569060

DESM
Desmin

1

19

High-throughput

0.691

High

821766

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.691

High

821768

AINX
Alpha-internexin

1

20

High-throughput

0.691

High

821814

K1C23
Keratin, type I cytoskeletal 23

1

20

High-throughput

0.691

High

821816

SYNCI
Syncoilin

1

20

High-throughput

0.691

High

539786

IDE
Insulin-degrading enzyme

3

13

Small-scale

0.670

High

346210

MYC
Myc proto-oncogene protein

3

20

High-throughput

0.640

High

821784

UBR1
E3 ubiquitin-protein ligase UBR1

2

6

High-throughput

0.628

High

821800

RSPRY
RING finger and SPRY domain-containing protein 1

2

15

High-throughput

0.628

High

821754

CDK5
Cyclin-dependent kinase 5

2

20

Small-scale

0.624

High

595135

LMNB1
Lamin-B1

1

20

High-throughput

0.618

High

408760

K1C18
Keratin, type I cytoskeletal 18

1

20

High-throughput

0.618

High

616611

MYF6
Myogenic factor 6

2

7

High-throughput

0.574

High

821802

F167A
Protein FAM167A

2

3

High-throughput

0.574

High

546073

MYOG
Myogenin

2

6

High-throughput

0.558

High

207544

RNF13
E3 ubiquitin-protein ligase RNF13

1

11

High-throughput

0.536

High

230490

TRAK2
Trafficking kinesin-binding protein 2

1

18

High-throughput

0.536

High

304066

UBR5
E3 ubiquitin-protein ligase UBR5

1

20

High-throughput

0.536

High

312904

SLU7
Pre-mRNA-splicing factor SLU7

1

2

High-throughput

0.536

High

313778

SVIL
Supervillin

1

8

High-throughput

0.536

High

427860

CAN1
Calpain-1 catalytic subunit

1

8

High-throughput

0.536

High

431645

HS90A
Heat shock protein HSP 90-alpha

1

10

High-throughput

0.536

High

575330

EGR1
Early growth response protein 1

1

10

High-throughput

0.536

High

725924

ADDA
Alpha-adducin

1

6

High-throughput

0.536

High

821752

ASCL1
Achaete-scute homolog 1

1

7

High-throughput

0.536

High

821756

GOGA2
Golgin subfamily A member 2

1

18

High-throughput

0.536

High

821757

FLII
Protein flightless-1 homolog

1

8

High-throughput

0.536

High

821767

STK11
Serine/threonine-protein kinase STK11

1

8

High-throughput

0.536

High

821769

HIF1A
Hypoxia-inducible factor 1-alpha

1

10

High-throughput

0.536

High

821772

GRDN
Girdin

1

19

High-throughput

0.536

High

821785

UBR2
E3 ubiquitin-protein ligase UBR2

1

6

High-throughput

0.536

High

821808

PKP4
Plakophilin-4

1

15

High-throughput

0.536

High

821810

NPAS1
Neuronal PAS domain-containing protein 1

1

9

High-throughput

0.536

High

821813

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

20

High-throughput

0.536

High

821815

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

12

High-throughput

0.536

High

821821

XPP3
Xaa-Pro aminopeptidase 3

1

2

High-throughput

0.536

High

821826

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

20

High-throughput

0.536

High

821765

RBP1
RalA-binding protein 1

2

20

High-throughput

0.521

High

821783

ARHGJ
Rho guanine nucleotide exchange factor 19

2

20

High-throughput

0.521

High

821796

DEP1B
DEP domain-containing protein 1B

2

12

High-throughput

0.521

High

821817

CCSE2
Serine-rich coiled-coil domain-containing protein 2

1

2

High-throughput

0.515

High

518608

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.513

High

685638

PRDX2
Peroxiredoxin-2

1

0

High-throughput

0.513

High

782871

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.513

High

215327

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

14

High-throughput

0.489

High

233976

NMD3B
Glutamate receptor ionotropic, NMDA 3B

1

9

High-throughput

0.489

High

254327

ATP9A
Probable phospholipid-transporting ATPase IIA

1

1

High-throughput

0.489

High

312210

IPO7
Importin-7

1

5

High-throughput

0.489

High

418911

TPM3
Tropomyosin alpha-3 chain

1

6

High-throughput

0.489

High

451217

TPM1
Tropomyosin alpha-1 chain

1

7

High-throughput

0.489

High

451391

CLCA
Clathrin light chain A

1

3

High-throughput

0.489

High

451648

CLCB
Clathrin light chain B

1

3

High-throughput

0.489

High

551090

ITF2
Transcription factor 4

1

1

High-throughput

0.489

High

599065

ZNF10
Zinc finger protein 10

1

3

High-throughput

0.489

High

631057

LAMA1
Laminin subunit alpha-1

1

1

High-throughput

0.489

High

661219

S10A2
Protein S100-A2

1

18

High-throughput

0.489

High

789210

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.489

High

821753

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

1

High-throughput

0.489

High

821758

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

12

High-throughput

0.489

High

821770

T132A
Transmembrane protein 132A

1

1

High-throughput

0.489

High

821771

S35G1
Solute carrier family 35 member G1

1

1

High-throughput

0.489

High

821773

CE162
Centrosomal protein of 162 kDa

1

20

High-throughput

0.489

High

821774

GRTP1
Growth hormone-regulated TBC protein 1

1

6

High-throughput

0.489

High

821778

FIGLA
Factor in the germline alpha

1

6

High-throughput

0.489

High

821782

CCD71
Coiled-coil domain-containing protein 71

1

1

High-throughput

0.489

High

821786

MILK2
MICAL-like protein 2

1

9

High-throughput

0.489

High

821787

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

9

High-throughput

0.489

High

821792

ZBT44
Zinc finger and BTB domain-containing protein 44

1

6

High-throughput

0.489

High

821794

CTCFL
Transcriptional repressor CTCFL

1

7

High-throughput

0.489

High

821798

NGN1
Neurogenin-1

1

8

High-throughput

0.489

High

821804

RN145
RING finger protein 145

1

20

High-throughput

0.489

High

821806

FER3L
Fer3-like protein

1

7

High-throughput

0.489

High

821812

SCRT1
Transcriptional repressor scratch 1

1

20

High-throughput

0.489

High

821819

GHC1
Mitochondrial glutamate carrier 1

1

3

High-throughput

0.489

High

821827

LAS1L
Ribosomal biogenesis protein LAS1L

1

1

High-throughput

0.489

High

148526

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.479

High

209768

PRC1
Protein regulator of cytokinesis 1

1

18

High-throughput

0.479

High

232807

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

20

High-throughput

0.479

High

233282

NUPR1
Nuclear protein 1

1

6

High-throughput

0.479

High

255587

OBSL1
Obscurin-like protein 1

1

20

High-throughput

0.479

High

277991

PIAS1
E3 SUMO-protein ligase PIAS1

1

11

High-throughput

0.479

High

384471

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.479

High

386300

P53
Cellular tumor antigen p53

1

11

Small-scale

0.479

High

503662

HSP7C
Heat shock cognate 71 kDa protein

1

9

High-throughput

0.479

High

590710

BTF3
Transcription factor BTF3

1

8

High-throughput

0.479

High

742123

SYUA
Alpha-synuclein

1

7

High-throughput

0.479

High

821755

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

821762

KEAP1
Kelch-like ECH-associated protein 1

1

6

Small-scale

0.479

High

821763

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

821764

CD5R1
Cyclin-dependent kinase 5 activator 1

1

1

Small-scale

0.479

High

821780

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

821790

CGAS
Cyclic GMP-AMP synthase

1

2

High-throughput

0.479

High

821797

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

19

High-throughput

0.479

High

821818

ECT2
Protein ECT2

1

20

High-throughput

0.479

High

821823

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

15

High-throughput

0.479

High

821779

DYH12
Dynein axonemal heavy chain 12

1

5

High-throughput

0.470

High

821801

TNIP3
TNFAIP3-interacting protein 3

1

20

High-throughput

0.470

High

821761

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

Small-scale

0.458

High

717551

BMI1
Polycomb complex protein BMI-1

1

20

High-throughput

0.445

High

821760

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

20

High-throughput

0.445

High

821795

CE192
Centrosomal protein of 192 kDa

1

2

High-throughput

0.445

High

821807

CK5P2
CDK5 regulatory subunit-associated protein 2

1

19

High-throughput

0.445

High

268625

SF3B1
Splicing factor 3B subunit 1

1

2

High-throughput

0.437

High

308501

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.437

High

649371

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.437

High

708577

MCM5
DNA replication licensing factor MCM5

1

19

High-throughput

0.437

High

821781

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

821788

SRRM1
Serine/arginine repetitive matrix protein 1

1

20

High-throughput

0.437

High

821793

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

19

Small-scale

0.437

High

821799

CHM4C
Charged multivesicular body protein 4c

1

12

High-throughput

0.437

High

821822

ANLN
Anillin

1

20

High-throughput

0.437

High

101761

F8W7C6
Large ribosomal subunit protein uL16

1

2

High-throughput

0.407

High

101798

F8WC19
Splicing factor 3b subunit 1

1

1

High-throughput

0.407

High

239853

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

8

High-throughput

0.407

High

302490

CE152
Centrosomal protein of 152 kDa

1

16

High-throughput

0.407

High

821759

CTBP1
C-terminal-binding protein 1

1

10

High-throughput

0.407

High

821776

CP135
Centrosomal protein of 135 kDa

1

19

High-throughput

0.407

High

821791

POC5
Centrosomal protein POC5

1

6

High-throughput

0.407

High

821805

CEP63
Centrosomal protein of 63 kDa

1

19

High-throughput

0.407

High

821809

ZBT18
Zinc finger and BTB domain-containing protein 18

1

13

High-throughput

0.407

High

92180

E9PAV9
G patch domain-containing protein 4

1

0

High-throughput

0.279

Low

127471

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

245191

RAMP1
Receptor activity-modifying protein 1

1

0

High-throughput

0.279

Low

604128

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.279

Low

821775

GKAP1
G kinase-anchoring protein 1

1

0

High-throughput

0.279

Low

821777

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

821789

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.279

Low

821811

CMS1
Protein CMSS1

1

0

High-throughput

0.279

Low

821824

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.279

Low

821825

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

409730

CO5A2

1

0

High-throughput

0.269

Low

821803

FA81B
Protein FAM81B

1

0

High-throughput

0.269

Low

821820

COE2
Transcription factor COE2

1

0

High-throughput

0.269

Low

390767

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024