Protein: HEN1
Helix-loop-helix protein 1 (HEN-1) (Class A basic helix-loop-helix protein 35) (bHLHa35) (Nescient helix loop helix 1) (NSCL-1)

Gene: HEN1, NHLH1
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q02575

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

551504

TFE2
Transcription factor E2-alpha

2

20

Small-scale

0.793

High

551121

ITF2
Transcription factor 4

1

20

High-throughput

0.691

High

971805

HTF4
Transcription factor 12

1

20

High-throughput

0.691

High

971788

CENPP
Centromere protein P

3

1

High-throughput

0.654

High

638265

RBTN2
Rhombotin-2

1

15

Small-scale

0.621

High

971790

MGAP
MAX gene-associated protein

1

3

High-throughput

0.618

High

550367

ZEP1
Zinc finger protein 40

2

7

High-throughput

0.586

High

971781

NFIA
Nuclear factor 1 A-type

1

5

High-throughput

0.561

High

135104

NFIB
Nuclear factor 1 B-type

1

5

High-throughput

0.501

High

971779

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.500

High

971804

HEXI2
Protein HEXIM2

1

3

High-throughput

0.500

High

971830

PDIP2
Polymerase delta-interacting protein 2

1

1

High-throughput

0.500

High

507562

PIM1
Serine/threonine-protein kinase pim-1

1

3

High-throughput

0.481

High

282058

CLPX
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

1

0

High-throughput

0.479

High

128144

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

2

High-throughput

0.479

High

152628

KMT2D
Histone-lysine N-methyltransferase 2D

1

11

High-throughput

0.479

High

183103

KDM6A
Lysine-specific demethylase 6A

1

4

High-throughput

0.479

High

299355

UBXN7
UBX domain-containing protein 7

1

2

High-throughput

0.479

High

321760

WIZ
Protein Wiz

1

7

High-throughput

0.479

High

741029

ZEB1
Zinc finger E-box-binding homeobox 1

1

6

High-throughput

0.479

High

801092

KI67
Proliferation marker protein Ki-67

1

5

High-throughput

0.479

High

830929

CTCF
Transcriptional repressor CTCF

1

5

High-throughput

0.479

High

846752

SMCA2
Probable global transcription activator SNF2L2

1

14

High-throughput

0.479

High

867574

BLM
RecQ-like DNA helicase BLM

1

4

High-throughput

0.479

High

952796

FOXK1
Forkhead box protein K1

1

2

High-throughput

0.479

High

964167

FOXK2
Forkhead box protein K2

1

2

High-throughput

0.479

High

971778

KMT2A
Histone-lysine N-methyltransferase 2A

1

5

High-throughput

0.479

High

971780

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

971782

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.479

High

971783

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.479

High

971785

ZN260
Zinc finger protein 260

1

3

High-throughput

0.479

High

971786

ARI4B
AT-rich interactive domain-containing protein 4B

1

8

High-throughput

0.479

High

971789

UBN2
Ubinuclein-2

1

5

High-throughput

0.479

High

971794

PHF10
PHD finger protein 10

1

10

High-throughput

0.479

High

971795

REQU
Zinc finger protein ubi-d4

1

15

High-throughput

0.479

High

971796

RL36L
Ribosomal protein eL42-like

1

1

High-throughput

0.479

High

971797

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

1

High-throughput

0.479

High

971798

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

6

High-throughput

0.479

High

971800

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

2

High-throughput

0.479

High

971801

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

5

High-throughput

0.479

High

971803

ZN512
Zinc finger protein 512

1

4

High-throughput

0.479

High

971806

NP1L4
Nucleosome assembly protein 1-like 4

1

1

High-throughput

0.479

High

971809

ARI3A
AT-rich interactive domain-containing protein 3A

1

5

High-throughput

0.479

High

971812

PCGF6
Polycomb group RING finger protein 6

1

2

High-throughput

0.479

High

971813

GTPB4
GTP-binding protein 4

1

2

High-throughput

0.479

High

971818

ZN644
Zinc finger protein 644

1

6

High-throughput

0.479

High

971820

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

4

High-throughput

0.479

High

971821

BRD7
Bromodomain-containing protein 7

1

14

High-throughput

0.479

High

971824

DDX56
Probable ATP-dependent RNA helicase DDX56

1

2

High-throughput

0.479

High

971827

TRPS1
Zinc finger transcription factor Trps1

1

9

High-throughput

0.479

High

971829

ZBT21
Zinc finger and BTB domain-containing protein 21

1

3

High-throughput

0.479

High

172421

NKRF
NF-kappa-B-repressing factor

1

0

High-throughput

0.458

High

836208

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.458

High

900132

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.458

High

971787

CDCA2
Cell division cycle-associated protein 2

1

0

High-throughput

0.458

High

971814

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

971815

REXO4
RNA exonuclease 4

1

0

High-throughput

0.458

High

971819

DDX31
ATP-dependent DNA helicase DDX31

1

0

High-throughput

0.458

High

971822

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

971826

CFDP1
Craniofacial development protein 1

1

0

High-throughput

0.458

High

971817

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.457

High

133447

NOP56
Nucleolar protein 56

1

1

High-throughput

0.437

High

271310

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.437

High

273079

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.437

High

802065

NOP2
Probable 28S rRNA

1

1

High-throughput

0.437

High

971784

BMS1
Ribosome biogenesis protein BMS1 homolog

1

1

High-throughput

0.437

High

971791

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

4

High-throughput

0.437

High

971792

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.437

High

971802

EP400
E1A-binding protein p400

1

12

High-throughput

0.437

High

971808

EBP2
Probable rRNA-processing protein EBP2

1

1

High-throughput

0.437

High

971816

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.437

High

971823

RBM28
RNA-binding protein 28

1

1

High-throughput

0.437

High

971831

NOP16
Nucleolar protein 16

1

1

High-throughput

0.437

High

971807

TCPH
T-complex protein 1 subunit eta

2

0

High-throughput

0.316

High

971793

IN80E
INO80 complex subunit E

1

0

High-throughput

0.251

Low

971828

PSME2
Proteasome activator complex subunit 2

1

0

High-throughput

0.251

Low

92211

E9PAV9
G patch domain-containing protein 4

1

0

High-throughput

0.249

Low

603148

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

0

High-throughput

0.249

Low

789428

RBM34
RNA-binding protein 34

1

0

High-throughput

0.249

Low

971799

DDX27
Probable ATP-dependent RNA helicase DDX27

1

0

High-throughput

0.249

Low

971810

CG050
Uncharacterized protein C7orf50

1

0

High-throughput

0.249

Low

971811

LLPH
Protein LLP homolog

1

0

High-throughput

0.249

Low

971825

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024