Protein: TRM2A
tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.35) (mRNA (uracil-5-)-methyltransferase TRMT2A) (EC 2.1.1.-)

Gene: TRM2A, TRMT2A
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q8IZ69

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005829 - cytosol
GO:0006397 - mRNA processing
GO:0008033 - tRNA processing
GO:0008169 - C-methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1224062

PASK
PAS domain-containing serine/threonine-protein kinase

3

1

High-throughput

0.667

High

403279

LA
Lupus La protein

3

0

High-throughput

0.646

High

166965

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

2

5

High-throughput

0.628

High

257196

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

2

2

High-throughput

0.628

High

257655

ANR17
Ankyrin repeat domain-containing protein 17

2

5

High-throughput

0.628

High

1074176

SF3A1
Splicing factor 3A subunit 1

2

1

High-throughput

0.628

High

1126006

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

2

2

High-throughput

0.628

High

1224082

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

2

2

High-throughput

0.628

High

1219781

ANKH1
Ankyrin repeat and KH domain-containing protein 1

2

5

High-throughput

0.611

High

1075607

TRBP2
RISC-loading complex subunit TARBP2

2

0

High-throughput

0.602

High

1224060

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

2

0

High-throughput

0.602

High

1224083

DICER
Endoribonuclease Dicer

2

0

High-throughput

0.602

High

617604

CRCM
Colorectal mutant cancer protein

2

0

High-throughput

0.580

High

1224074

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

395155

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.577

High

779718

CCNF
Cyclin-F

2

0

High-throughput

0.576

High

1224046

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

2

5

High-throughput

0.574

High

1224047

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

2

5

High-throughput

0.574

High

1224052

APBP2
Amyloid protein-binding protein 2

2

1

High-throughput

0.553

High

933887

TBB4B
Tubulin beta-4B chain

1

1

High-throughput

0.536

High

1224053

IRF7
Interferon regulatory factor 7

1

1

High-throughput

0.536

High

347291

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.533

High

501066

IRF1
Interferon regulatory factor 1

1

1

High-throughput

0.515

High

135464

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

0

High-throughput

0.513

High

216759

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

High-throughput

0.513

High

243493

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.513

High

513879

DMD
Dystrophin

1

0

High-throughput

0.513

High

614220

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.513

High

840520

VASP
Vasodilator-stimulated phosphoprotein

1

0

High-throughput

0.513

High

1018833

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.513

High

1146353

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

0

High-throughput

0.513

High

1185218

DHX32
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

1

0

High-throughput

0.513

High

1224069

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.513

High

1224070

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.513

High

1224075

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.513

High

1224076

ANM7
Protein arginine N-methyltransferase 7

1

0

High-throughput

0.513

High

515468

CDK4
Cyclin-dependent kinase 4

1

1

High-throughput

0.508

High

596413

RASA1
Ras GTPase-activating protein 1

1

1

High-throughput

0.508

High

1224051

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

2

High-throughput

0.508

High

665627

EPHB2
Ephrin type-B receptor 2

1

2

High-throughput

0.500

High

208920

FOXS1
Forkhead box protein S1

1

2

High-throughput

0.489

High

270815

FOXH1
Forkhead box protein H1

1

2

High-throughput

0.489

High

622961

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

1

High-throughput

0.489

High

665498

EPHA8
Ephrin type-A receptor 8

1

2

High-throughput

0.489

High

885171

FOXL2
Forkhead box protein L2

1

2

High-throughput

0.489

High

1021320

FOXL1
Forkhead box protein L1

1

2

High-throughput

0.489

High

1046510

TBB2A
Tubulin beta-2A chain

1

1

High-throughput

0.489

High

1072542

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.489

High

1224050

OIT3
Oncoprotein-induced transcript 3 protein

1

1

High-throughput

0.489

High

378739

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

589216

ANXA7
Annexin A7

1

0

High-throughput

0.486

High

758283

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

1026313

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.486

High

1037989

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.486

High

1084833

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

476038

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

846492

BLK
Tyrosine-protein kinase Blk

1

1

High-throughput

0.479

High

882424

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

1151114

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

309861

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

1

High-throughput

0.464

High

578459

RCC1
Regulator of chromosome condensation

1

1

High-throughput

0.464

High

296946

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.458

High

319914

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

442301

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

848420

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.458

High

1034923

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

1042001

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1063945

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1101155

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1215856

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.458

High

1224054

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1224057

RBM33
RNA-binding protein 33

1

0

High-throughput

0.458

High

1224065

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1224077

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1224079

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

838113

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

338680

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.437

High

379600

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

1224073

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1224081

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

Small-scale

0.437

High

374518

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.426

High

402233

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1085431

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.426

High

92424

E9PDP5
Ankyrin repeat and KH domain containing 1

1

5

High-throughput

0.407

High

1223430

THNS1
Threonine synthase-like 1

2

0

High-throughput

0.328

High

1224061

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

2

0

High-throughput

0.328

High

1224064

ERBIN
Erbin

2

0

High-throughput

0.328

High

1224066

ATP5S
ATP synthase subunit s, mitochondrial

2

0

High-throughput

0.328

High

1224072

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

2

0

High-throughput

0.328

High

1224080

FEZ2
Fasciculation and elongation protein zeta-2

2

0

High-throughput

0.328

High

1224086

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

2

0

High-throughput

0.328

High

993498

TLE5
TLE family member 5

2

0

High-throughput

0.316

High

1058363

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

1224056

ZN837
Zinc finger protein 837

2

0

High-throughput

0.316

High

146368

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

0

High-throughput

0.279

Low

224987

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

245368

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

420749

KLK1
Kallikrein-1

1

0

High-throughput

0.279

Low

441622

TRFM
Melanotransferrin

1

0

High-throughput

0.279

Low

516078

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.279

Low

557192

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.279

Low

606908

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.279

Low

661345

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

789640

I12R1
Interleukin-12 receptor subunit beta-1

1

0

High-throughput

0.279

Low

796131

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.279

Low

873722

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.279

Low

885380

LOXL3
Lysyl oxidase homolog 3

1

0

High-throughput

0.279

Low

989248

FMOD
Fibromodulin

1

0

High-throughput

0.279

Low

1037480

ASAH1
Acid ceramidase

1

0

High-throughput

0.279

Low

1044380

PTC1
Protein patched homolog 1

1

0

High-throughput

0.279

Low

1128467

EFHC1
EF-hand domain-containing protein 1

1

0

High-throughput

0.279

Low

1191646

BTLA
B- and T-lymphocyte attenuator

1

0

High-throughput

0.279

Low

1202295

TXND2
Thioredoxin domain-containing protein 2

1

0

High-throughput

0.279

Low

1205531

TMM25
Transmembrane protein 25

1

0

High-throughput

0.279

Low

1224044

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.279

Low

1224045

KCD17
BTB/POZ domain-containing protein KCTD17

1

0

High-throughput

0.279

Low

1224048

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1224049

DCA11
DDB1- and CUL4-associated factor 11

1

0

High-throughput

0.279

Low

1224055

TTC28
Tetratricopeptide repeat protein 28

1

0

High-throughput

0.279

Low

1224059

DCAF5
DDB1- and CUL4-associated factor 5

1

0

High-throughput

0.279

Low

1224067

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.279

Low

1224068

UPK3B
Uroplakin-3b

1

0

High-throughput

0.279

Low

1224071

RTN4R
Reticulon-4 receptor

1

0

High-throughput

0.279

Low

1224084

LAMP3
Lysosome-associated membrane glycoprotein 3

1

0

High-throughput

0.279

Low

1224085

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.279

Low

997658

DMWD
Dystrophia myotonica WD repeat-containing protein

1

0

High-throughput

0.269

Low

155695

TNF11
Tumor necrosis factor ligand superfamily member 11

1

0

High-throughput

0.265

Low

393463

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

High-throughput

0.265

Low

164418

TRI66
Tripartite motif-containing protein 66

1

0

High-throughput

0.249

Low

319258

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

1019021

TP53B
TP53-binding protein 1

1

0

High-throughput

0.249

Low

1170751

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1224058

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1224063

CIC
Protein capicua homolog

1

0

High-throughput

0.249

Low

1224078

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024