Protein: INVO
Involucrin

Gene: INVO, IVL
Organism: Homo sapiens
Interactions: 133
UniProt ID: P07476

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0010224 - response to UV-B

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

428627

RBM24
RNA-binding protein 24

3

7

High-throughput

0.667

High

365127

FRIH
Ferritin heavy chain

2

2

High-throughput

0.628

High

428620

CDK15
Cyclin-dependent kinase 15

2

5

High-throughput

0.628

High

428590

MYOME
Myomegalin

2

3

High-throughput

0.611

High

428650

DD19B
ATP-dependent RNA helicase DDX19B

2

2

High-throughput

0.611

High

428552

ZSC20
Zinc finger and SCAN domain-containing protein 20

3

1

High-throughput

0.609

High

428583

KI3S1
Killer cell immunoglobulin-like receptor 3DS1

3

1

High-throughput

0.609

High

428617

GMCL1
Germ cell-less protein-like 1

3

2

High-throughput

0.609

High

428635

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

3

1

High-throughput

0.609

High

351511

ANF
Natriuretic peptides A

2

0

High-throughput

0.602

High

428585

ZIC1
Zinc finger protein ZIC 1

2

0

High-throughput

0.602

High

428615

RNF25
E3 ubiquitin-protein ligase RNF25

2

0

High-throughput

0.602

High

428561

MPI
Mannose-6-phosphate isomerase

2

0

High-throughput

0.585

High

428602

FRMD1
FERM domain-containing protein 1

2

7

High-throughput

0.574

High

428637

SHCAF
SIN3-HDAC complex-associated factor

2

1

High-throughput

0.574

High

428640

TB22B
TBC1 domain family member 22B

2

1

High-throughput

0.574

High

428653

FCF1
rRNA-processing protein FCF1 homolog

2

1

High-throughput

0.574

High

428614

ACD
Adrenocortical dysplasia protein homolog

1

1

High-throughput

0.568

High

428580

ITA9
Integrin alpha-9

2

3

High-throughput

0.558

High

125959

UPK1A
Uroplakin-1a

1

5

High-throughput

0.536

High

209306

TSN6
Tetraspanin-6

1

4

High-throughput

0.536

High

428553

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.536

High

428560

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.536

High

428571

SSBP2
Single-stranded DNA-binding protein 2

1

2

High-throughput

0.536

High

428575

EF1A2
Elongation factor 1-alpha 2

1

2

High-throughput

0.536

High

428577

FSTL1
Follistatin-related protein 1

1

2

High-throughput

0.536

High

428578

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

1

High-throughput

0.536

High

428584

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.536

High

428596

CERS3
Ceramide synthase 3

1

2

High-throughput

0.536

High

428619

FMNL2
Formin-like protein 2

1

2

High-throughput

0.536

High

428629

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.536

High

428638

MBNL1
Muscleblind-like protein 1

1

2

High-throughput

0.536

High

428642

KLH11
Kelch-like protein 11

1

3

High-throughput

0.536

High

428643

GID8
Glucose-induced degradation protein 8 homolog

1

1

High-throughput

0.536

High

428648

HDAC9
Histone deacetylase 9

1

7

High-throughput

0.536

High

428652

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.536

High

428654

CHMP3
Charged multivesicular body protein 3

1

3

High-throughput

0.536

High

428656

RN115
E3 ubiquitin-protein ligase RNF115

1

1

High-throughput

0.536

High

183014

P2RX6
P2X purinoceptor 6

1

0

High-throughput

0.513

High

274902

RENR
Renin receptor

1

0

High-throughput

0.513

High

329072

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

428566

PCP4
Calmodulin regulator protein PCP4

1

0

High-throughput

0.513

High

428568

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

428572

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

428573

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

0

High-throughput

0.513

High

428574

HSF2
Heat shock factor protein 2

1

0

High-throughput

0.513

High

428591

JADE1
Protein Jade-1

1

0

High-throughput

0.513

High

428611

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

428613

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

428623

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.513

High

428625

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.513

High

428628

5NT1A
Cytosolic 5'-nucleotidase 1A

1

0

High-throughput

0.513

High

428630

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

380536

K2C1
Keratin, type II cytoskeletal 1

1

2

Small-scale

0.501

High

428546

INVO
Involucrin

1

11

Small-scale

0.501

High

428551

DESP
Desmoplakin

1

6

Small-scale

0.501

High

428564

CRK
Adapter molecule crk

1

14

High-throughput

0.501

High

428657

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

2

Small-scale

0.501

High

428641

POTE1
Protection of telomeres protein 1

1

1

High-throughput

0.494

High

428579

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.493

High

239717

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.489

High

303632

OR2A4
Olfactory receptor 2A4

1

1

High-throughput

0.489

High

319492

LY86
Lymphocyte antigen 86

1

1

High-throughput

0.489

High

428554

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

2

High-throughput

0.489

High

428555

PO3F3
POU domain, class 3, transcription factor 3

1

3

High-throughput

0.489

High

428576

GABPA
GA-binding protein alpha chain

1

3

High-throughput

0.489

High

428586

CR021
UPF0711 protein C18orf21

1

1

High-throughput

0.489

High

428588

FNDC1
Fibronectin type III domain-containing protein 1

1

8

High-throughput

0.489

High

428589

LRC10
Leucine-rich repeat-containing protein 10

1

2

High-throughput

0.489

High

428592

DPPA4
Developmental pluripotency-associated protein 4

1

2

High-throughput

0.489

High

428593

ZN550
Zinc finger protein 550

1

2

High-throughput

0.489

High

428600

AN36B
Ankyrin repeat domain-containing protein 36B

1

9

High-throughput

0.489

High

428604

FNDC5
Fibronectin type III domain-containing protein 5

1

4

High-throughput

0.489

High

428606

O13C3
Olfactory receptor 13C3

1

1

High-throughput

0.489

High

428607

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

1

High-throughput

0.489

High

428610

ZDH19
Palmitoyltransferase ZDHHC19

1

1

High-throughput

0.489

High

428622

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

1

High-throughput

0.489

High

428624

SH23A
SH2 domain-containing protein 3A

1

17

High-throughput

0.489

High

428632

ZDHC6
Palmitoyltransferase ZDHHC6

1

2

High-throughput

0.489

High

428647

PHF11
PHD finger protein 11

1

4

High-throughput

0.489

High

428649

COR1C
Coronin-1C

1

9

High-throughput

0.489

High

345043

CYTA
Cystatin-A

1

0

Small-scale

0.480

High

428556

LORI
Loricrin

1

0

Small-scale

0.480

High

427027

CATD
Cathepsin D

1

1

High-throughput

0.479

High

428547

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

6

High-throughput

0.479

High

428548

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

428550

CADH1
Cadherin-1

1

4

High-throughput

0.479

High

428557

SPB3
Serpin B3

1

1

High-throughput

0.479

High

428558

CASPE
Caspase-14

1

1

High-throughput

0.479

High

428559

1433S
14-3-3 protein sigma

1

15

High-throughput

0.479

High

428562

SPB5
Serpin B5

1

1

High-throughput

0.479

High

428565

LEG7
Galectin-7

1

1

High-throughput

0.479

High

428570

ACTA
Actin, aortic smooth muscle

1

9

High-throughput

0.479

High

428581

PKP1
Plakophilin-1

1

6

High-throughput

0.479

High

428587

Q4LE69
1-phosphatidylinositol 4-kinase

1

7

High-throughput

0.479

High

428631

FACD2
Fanconi anemia group D2 protein

1

4

High-throughput

0.479

High

428633

RANB3
Ran-binding protein 3

1

1

High-throughput

0.479

High

309648

KAT7
Histone acetyltransferase KAT7

1

0

High-throughput

0.458

High

428582

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.458

High

428605

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

428644

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

428563

PI4KA
Phosphatidylinositol 4-kinase alpha

1

7

High-throughput

0.445

High

428645

CALL5
Calmodulin-like protein 5

1

1

High-throughput

0.437

High

428655

LOXL2
Lysyl oxidase homolog 2

1

3

High-throughput

0.437

High

92433

E9PDS3
Integrin subunit alpha 9

1

3

High-throughput

0.407

High

428603

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

5

High-throughput

0.407

High

428618

SUSD3
Sushi domain-containing protein 3

3

0

High-throughput

0.347

High

428636

UD110
UDP-glucuronosyltransferase 1A10

3

0

High-throughput

0.347

High

428601

CCYL1
Cyclin-Y-like protein 1

2

0

High-throughput

0.328

High

428634

ACAD9
Complex I assembly factor ACAD9, mitochondrial

2

0

High-throughput

0.328

High

200802

ZSC12
Zinc finger and SCAN domain-containing protein 12

2

0

High-throughput

0.288

High

213684

LIAS
Lipoyl synthase, mitochondrial

1

0

High-throughput

0.279

Low

215797

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

0

High-throughput

0.279

Low

305341

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.279

Low

309355

MBD4
Methyl-CpG-binding domain protein 4

1

0

High-throughput

0.279

Low

428549

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.279

Low

428567

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

428569

DSCR6
Protein ripply3

1

0

High-throughput

0.279

Low

428594

BPHL
Valacyclovir hydrolase

1

0

High-throughput

0.279

Low

428595

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.279

Low

428598

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.279

Low

428599

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

428608

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

428612

PIGT
GPI transamidase component PIG-T

1

0

High-throughput

0.279

Low

428616

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

428621

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

428626

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

428639

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.279

Low

428646

DKK2
Dickkopf-related protein 2

1

0

High-throughput

0.279

Low

428651

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.279

Low

428609

POF1B
Protein POF1B

1

0

High-throughput

0.249

Low

428597

LACC1
Purine nucleoside phosphorylase LACC1

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024