Protein: TFE2
Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1)

Gene: TFE2, Tcf3
Organism: Mus musculus
Interactions: 116
UniProt ID: P15806

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

550184

ID2
DNA-binding protein inhibitor ID-2

5

20

Small-scale

0.907

High

550202

ASCL1
Achaete-scute homolog 1

4

20

Small-scale

0.888

High

550176

TFE2
Transcription factor E2-alpha

3

13

Small-scale

0.835

High

550182

TWST1
Twist-related protein 1

2

20

Small-scale

0.821

High

550180

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

2

20

Small-scale

0.806

High

550254

ASCL3
Achaete-scute homolog 3

2

20

Small-scale

0.786

High

550183

ID3
DNA-binding protein inhibitor ID-3

2

20

Small-scale

0.783

High

550211

HAND2
Heart- and neural crest derivatives-expressed protein 2

2

20

Small-scale

0.783

High

550252

OLIG2
Oligodendrocyte transcription factor 2

2

20

Small-scale

0.776

High

485935

MYOD1
Myoblast determination protein 1

2

12

Small-scale

0.757

High

550241

FER3L
Fer3-like protein

1

20

Small-scale

0.680

High

550248

BHE41
Class E basic helix-loop-helix protein 41

1

8

Small-scale

0.680

High

550255

OLIG1
Oligodendrocyte transcription factor 1

1

20

Small-scale

0.665

High

550195

PDLI4
PDZ and LIM domain protein 4

1

0

High-throughput

0.663

High

550216

HAND1
Heart- and neural crest derivatives-expressed protein 1

1

20

Small-scale

0.653

High

550197

NGN2
Neurogenin-2

1

20

Small-scale

0.647

High

550204

ITF2
Transcription factor 4

1

13

Small-scale

0.647

High

550212

HTF4
Transcription factor 12

1

13

Small-scale

0.647

High

550193

UBC9
SUMO-conjugating enzyme UBC9

3

2

Small-scale

0.637

High

550181

RBTN2
Rhombotin-2

1

6

Small-scale

0.621

High

550205

TCF15
Transcription factor 15

1

20

Small-scale

0.621

High

550207

NDF1
Neurogenic differentiation factor 1

1

20

Small-scale

0.621

High

550218

Q6GTZ3
Idb1 protein

1

20

Small-scale

0.621

High

550186

ATOH1
Transcription factor Atoh1

1

20

Small-scale

0.618

High

192773

TCF21
Transcription factor 21

1

20

High-throughput

0.590

High

550178

ID1
DNA-binding protein inhibitor ID-1

1

20

High-throughput

0.590

High

454939

CADH1
Cadherin-1

2

0

Small-scale

0.571

High

192265

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

1

High-throughput

0.541

High

222662

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

5

High-throughput

0.541

High

291777

NEMO
NF-kappa-B essential modulator

1

2

High-throughput

0.541

High

550185

BRCA1
Breast cancer type 1 susceptibility protein homolog

1

2

High-throughput

0.541

High

550187

FOXP1
Forkhead box protein P1

1

1

High-throughput

0.541

High

550199

C2TA
MHC class II transactivator

1

1

High-throughput

0.541

High

550224

JADE1
Protein Jade-1

1

7

High-throughput

0.541

High

550234

ERCC8
DNA excision repair protein ERCC-8

1

3

High-throughput

0.541

High

550246

PBX4
Pre-B-cell leukemia transcription factor 4

1

1

High-throughput

0.541

High

550253

RNF14
E3 ubiquitin-protein ligase RNF14

1

3

High-throughput

0.541

High

550260

TLE6
Transducin-like enhancer protein 6

1

6

High-throughput

0.541

High

550219

RGPA1
Ral GTPase-activating protein subunit alpha-1

1

0

Small-scale

0.529

High

93669

ZN277
Zinc finger protein 277

1

0

High-throughput

0.518

High

550196

GFI1
Zinc finger protein Gfi-1

1

0

High-throughput

0.518

High

550200

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

1

0

High-throughput

0.518

High

550201

MEIS2
Homeobox protein Meis2

1

0

High-throughput

0.518

High

550226

RFX4
Transcription factor RFX4

1

0

High-throughput

0.518

High

550239

NS1BP
Influenza virus NS1A-binding protein homolog

1

0

High-throughput

0.518

High

550242

CERS2
Ceramide synthase 2

1

0

High-throughput

0.518

High

550251

RAI14
Ankycorbin

1

0

High-throughput

0.518

High

550256

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.518

High

550257

PHF2
Lysine-specific demethylase PHF2

1

0

High-throughput

0.518

High

550262

PAPOB
Poly(A) polymerase beta

1

0

High-throughput

0.518

High

550264

T22D3
TSC22 domain family protein 3

1

0

High-throughput

0.518

High

550265

ZN292
Zinc finger protein 292

1

0

High-throughput

0.518

High

222892

MTG16
Protein CBFA2T3

1

9

Small-scale

0.501

High

550214

TRI27
Zinc finger protein RFP

1

2

Small-scale

0.501

High

550208

ELAV2
ELAV-like protein 2

1

1

High-throughput

0.494

High

550229

ZDH15
Palmitoyltransferase ZDHHC15

1

2

High-throughput

0.494

High

550232

SWAHC
Ankyrin repeat domain-containing protein SOWAHC

1

3

High-throughput

0.494

High

550249

ZDHC6
Palmitoyltransferase ZDHHC6

1

2

High-throughput

0.494

High

550222

MED16
Mediator of RNA polymerase II transcription subunit 16

1

1

High-throughput

0.481

High

140178

GATA2
Endothelial transcription factor GATA-2

1

2

Small-scale

0.479

High

250866

1433S
14-3-3 protein sigma

1

2

High-throughput

0.479

High

449412

NUCL
Nucleolin

1

2

High-throughput

0.479

High

502742

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

1

High-throughput

0.479

High

521649

PDCD6
Programmed cell death protein 6

1

1

High-throughput

0.479

High

533895

DNMT1
DNA

1

1

High-throughput

0.479

High

550188

IF4A1
Eukaryotic initiation factor 4A-I

1

6

High-throughput

0.479

High

550191

H4
Histone H4

1

1

High-throughput

0.479

High

550194

1433T
14-3-3 protein theta

1

2

High-throughput

0.479

High

550198

LDB1
LIM domain-binding protein 1

1

2

Small-scale

0.479

High

550203

SMCA4
Transcription activator BRG1

1

4

High-throughput

0.479

High

550206

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

550209

RBBP4
Histone-binding protein RBBP4

1

1

High-throughput

0.479

High

550210

RBBP7
Histone-binding protein RBBP7

1

1

High-throughput

0.479

High

550217

H2A2B
Histone H2A type 2-B

1

1

High-throughput

0.479

High

550220

SRSF1
Serine/arginine-rich splicing factor 1

1

1

High-throughput

0.479

High

550221

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

4

High-throughput

0.479

High

550223

RIGI
Antiviral innate immune response receptor RIG-I

1

3

High-throughput

0.479

High

550225

DACT2
Dapper homolog 2

1

2

Small-scale

0.479

High

550227

H2A3
Histone H2A type 3

1

1

High-throughput

0.479

High

550231

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

2

High-throughput

0.479

High

550243

FOXP3
Forkhead box protein P3

1

1

Small-scale

0.479

High

550244

NONO
Non-POU domain-containing octamer-binding protein

1

3

High-throughput

0.479

High

550247

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.479

High

550259

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

Small-scale

0.479

High

550263

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

2

High-throughput

0.479

High

93239

E9PWG6
Non-SMC condensin I complex, subunit G

1

0

High-throughput

0.458

High

193560

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

0

High-throughput

0.458

High

250565

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.458

High

476666

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

0

High-throughput

0.458

High

524502

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

534676

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

536037

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

550177

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

550189

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.458

High

550190

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.458

High

550192

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

550213

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

550230

Q8BQ46
TAF15 RNA polymerase II, TATA box binding protein

1

0

High-throughput

0.458

High

550233

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

High-throughput

0.458

High

550235

PAK2
Serine/threonine-protein kinase PAK 2

1

0

High-throughput

0.458

High

550236

CND1
Condensin complex subunit 1

1

0

High-throughput

0.458

High

550237

RFC3
Replication factor C subunit 3

1

0

High-throughput

0.458

High

550238

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.458

High

550240

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.458

High

550245

PARK7
Parkinson disease protein 7 homolog

1

0

High-throughput

0.458

High

550250

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

550258

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.458

High

550261

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

0

High-throughput

0.458

High

102304

G3UW74
Mediator of RNA polymerase II transcription subunit 16

1

1

High-throughput

0.457

High

550215

PHLA1
Pleckstrin homology-like domain family A member 1

1

0

High-throughput

0.438

High

496126

IF4A2
Eukaryotic initiation factor 4A-II

1

4

High-throughput

0.437

High

550179

FCER2
Low affinity immunoglobulin epsilon Fc receptor

1

1

Small-scale

0.437

High

192458

PKD2
Polycystin-2

1

0

Small-scale

0.426

High

515981

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

Small-scale

0.305

High

550228

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024