Protein: DOK2
Docking protein 2 (Dok-related protein) (Dok-R) (Downstream of tyrosine kinase 2) (IL-four receptor-interacting protein) (FRIP) (p56(dok-2))

Gene: DOK2
Organism: Mus musculus
Interactions: 13
UniProt ID: O70469

Gene Ontology (top 5):
GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005737 - cytoplasm
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007265 - Ras protein signal transduction
GO:0043409 - negative regulation of MAPK cascade

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

93301

E9PYG6
RAS p21 protein activator 1

3

20

Small-scale

0.739

High

223005

NCK2
Cytoplasmic protein NCK2

2

20

Small-scale

0.705

High

250952

DOK1
Docking protein 1

1

11

High-throughput

0.691

High

250949

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.690

High

250956

Q91YX7
RAS p21 protein activator 1

2

20

Small-scale

0.679

High

250948

ABL1
Tyrosine-protein kinase ABL1

1

20

Small-scale

0.665

High

250951

CSK
Tyrosine-protein kinase CSK

1

20

Small-scale

0.665

High

250957

NCK1
SH2/SH3 adapter protein Nck1

1

20

High-throughput

0.618

High

250953

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.618

High

250954

BCR
Breakpoint cluster region protein

1

4

High-throughput

0.553

High

250950

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.527

High

250958

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

1

7

High-throughput

0.489

High

250955

BICD1
Protein bicaudal D homolog 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024