Protein: BRCA1
Breast cancer type 1 susceptibility protein homolog (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BRCA1)

Gene: BRCA1
Organism: Mus musculus
Interactions: 26
UniProt ID: P48754

Gene Ontology (top 5):
GO:0000152 - nuclear ubiquitin ligase complex
GO:0000724 - double-strand break repair via homologous recombination
GO:0000793 - condensed chromosome
GO:0000794 - condensed nuclear chromosome
GO:0000800 - lateral element

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476705

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

18

High-throughput

0.647

High

822732

BRCA1
Breast cancer type 1 susceptibility protein homolog

1

15

Small-scale

0.647

High

822733

BRCA2
Breast cancer type 2 susceptibility protein homolog

3

4

Small-scale

0.642

High

822736

PALB2
Partner and localizer of BRCA2

2

1

Small-scale

0.571

High

562974

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

9

Small-scale

0.561

High

631273

PO2F1
POU domain, class 2, transcription factor 1

1

6

Small-scale

0.561

High

550185

TFE2
Transcription factor E2-alpha

1

2

High-throughput

0.541

High

678760

HXA2
Homeobox protein Hox-A2

1

4

High-throughput

0.541

High

822739

EWS
RNA-binding protein EWS

1

19

High-throughput

0.541

High

822744

HXC12
Homeobox protein Hox-C12

1

11

High-throughput

0.541

High

822746

OLIG1
Oligodendrocyte transcription factor 1

1

3

High-throughput

0.541

High

822738

EZH2
Histone-lysine N-methyltransferase EZH2

1

14

Small-scale

0.536

High

822742

SUZ12
Polycomb protein Suz12

1

3

Small-scale

0.536

High

822734

NF1
Neurofibromin

1

2

Small-scale

0.501

High

93886

E9QPK4
Serine/threonine-protein kinase ATR

1

16

Small-scale

0.479

High

404126

JUN
Transcription factor Jun

1

15

Small-scale

0.479

High

587096

ESR1
Estrogen receptor

1

20

Small-scale

0.479

High

657803

ETV4
ETS translocation variant 4

1

7

Small-scale

0.479

High

822735

RAD51
DNA repair protein RAD51 homolog 1

1

6

Small-scale

0.479

High

822737

ACACA
Acetyl-CoA carboxylase 1

1

6

Small-scale

0.479

High

822740

NPM
Nucleophosmin

1

5

Small-scale

0.479

High

822741

SMCA2
Probable global transcription activator SNF2L2

1

12

Small-scale

0.479

High

822743

NANOG
Homeobox protein NANOG

1

7

High-throughput

0.479

High

822745

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

1

Small-scale

0.479

High

822747

CAF1A
Chromatin assembly factor 1 subunit A

1

8

High-throughput

0.479

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024