Protein: Q8I103
Tight junction protein ZO-1

Gene: Q8I103, zoo-1
Organism: Caenorhabditis elegans
Interactions: 21
UniProt ID: Q8I103

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0005923 - bicellular tight junction
GO:0007015 - actin filament organization
GO:0009792 - embryo development ending in birth or egg hatching

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

232983

O44490
ELKS/RAB6-interacting/CAST family member 2

2

3

High-throughput

0.533

High

195521

O16500
Activated in Blocked Unfolded protein response

1

3

High-throughput

0.518

High

195548

O16511
Activated in Blocked Unfolded protein response

1

5

High-throughput

0.494

High

233411

O44606

1

5

High-throughput

0.494

High

233600

O44820
Ubiquitin-like domain-containing protein

1

5

High-throughput

0.494

High

1170253

Q21465
Ig-like domain-containing protein

1

12

High-throughput

0.494

High

1170929

Q22574
Laminin G domain-containing protein

1

8

High-throughput

0.494

High

1301287

Q8MXU3
ATP-grasp domain-containing protein

1

3

High-throughput

0.494

High

1301289

Q9TXM1
Uncharacterized protein

1

0

High-throughput

0.458

High

1301286

Q8IU04
RING-type domain-containing protein

1

1

High-throughput

0.439

High

758971

PLK1
Serine/threonine-protein kinase plk-1

1

2

High-throughput

0.437

High

1197153

Q4VNJ8
LIN-65S

1

1

High-throughput

0.417

High

1301285

CDK17
Cyclin-dependent kinase 17

1

7

High-throughput

0.417

High

145411

CNP3
Calcineurin-interacting protein 3

1

0

High-throughput

0.282

High

195300

O16274
Histone H3-K79 methyltransferase

1

0

High-throughput

0.282

High

303929

O76449
Protein F37C4.5

1

0

High-throughput

0.282

High

1165934

Q18257
Methyltransferase BUD23

1

0

High-throughput

0.282

High

1165940

Q18271
Ig-like domain-containing protein

1

0

High-throughput

0.282

High

1170300

Q21563
Activated in Blocked Unfolded protein response

1

0

High-throughput

0.282

High

96435

E9P875
Neurexin-3-beta

1

0

High-throughput

0.249

Low

1301288

Q9N413
Platelet-derived growth factor

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025