Protein: NOT
Ubiquitin carboxyl-terminal hydrolase nonstop (EC 3.4.19.12) (Deubiquitinating enzyme nonstop) (Ubiquitin thioesterase nonstop) (Ubiquitin-specific-processing protease nonstop)

Gene: NOT
Organism: Drosophila melanogaster
Interactions: 18
UniProt ID: Q9VVR1

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0006325 - chromatin organization
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1487427

SGF11
SAGA-associated factor 11 homolog

4

4

Small-scale

0.881

High

1487428

ENY2
Enhancer of yellow 2 transcription factor

2

3

Small-scale

0.754

High

509811

UBIQP
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

Small-scale

0.647

High

1302196

TAD2B
Transcriptional adapter 2b

3

6

Small-scale

0.640

High

1486388

Q9VTZ1
histone acetyltransferase

3

14

Small-scale

0.640

High

1470609

TAF5L
Protein will decrease acetylation

1

8

Small-scale

0.618

High

1474602

SPT3
SAGA complex subunit Spt3

2

3

Small-scale

0.584

High

1484080

ATX7
Ataxin-7

2

0

Small-scale

0.559

High

1169497

Q1WWH6
RE42507p

1

1

Small-scale

0.481

High

1304475

TAD12
Transcriptional adapter 1-2

1

3

Small-scale

0.479

High

1472883

Q9VEL2
B-related factor 1

1

3

Small-scale

0.479

High

1487429

SGF29
SAGA-associated factor 29kDa

1

3

Small-scale

0.479

High

99176

F2FB81
Wiskott-Aldrich syndrome protein family member

1

0

Small-scale

0.458

High

120015

M9PC25
SAGA factor-like TAF6, isoform B

1

0

Small-scale

0.458

High

1476224

SF3B5
Splicing factor 3B subunit 5

1

0

Small-scale

0.458

High

356043

O96757
Dof protein

1

1

Small-scale

0.457

High

303755

O76216
histone acetyltransferase

1

14

Small-scale

0.445

High

1473519

Q9VF25
PSEA-binding protein 45kD

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025