Protein: ALDOA
Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase)

Gene: ALDOA
Organism: Homo sapiens
Interactions: 228
UniProt ID: P04075

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003779 - actin binding
GO:0004332 - fructose-bisphosphate aldolase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

375855

ALDOC
Fructose-bisphosphate aldolase C

11

9

High-throughput

0.980

High

375838

ALDOA
Fructose-bisphosphate aldolase A

5

9

Small-scale

0.922

High

375844

ALDOB
Fructose-bisphosphate aldolase B

2

9

High-throughput

0.793

High

226224

PRKN
E3 ubiquitin-protein ligase parkin

4

5

High-throughput

0.686

High

375861

CFTR
Cystic fibrosis transmembrane conductance regulator

3

1

High-throughput

0.662

High

375901

HD
Huntingtin

2

2

High-throughput

0.621

High

375849

ENOA
Alpha-enolase

2

2

High-throughput

0.614

High

375863

ENOB
Beta-enolase

2

2

High-throughput

0.614

High

375939

CUL3
Cullin-3

2

3

High-throughput

0.611

High

337738

EGFR
Epidermal growth factor receptor

2

5

Small-scale

0.608

High

329219

AGR2
Anterior gradient protein 2 homolog

2

1

Small-scale

0.601

High

375845

ISG15
Ubiquitin-like protein ISG15

2

9

High-throughput

0.601

High

375856

TAU
Microtubule-associated protein tau

2

5

High-throughput

0.601

High

375968

CARM1
Histone-arginine methyltransferase CARM1

2

0

High-throughput

0.595

High

336296

SODC
Superoxide dismutase [Cu-Zn]

2

0

High-throughput

0.585

High

376015

MET14
N6-adenosine-methyltransferase non-catalytic subunit

2

0

High-throughput

0.585

High

375925

1433Z
14-3-3 protein zeta/delta

2

5

Small-scale

0.584

High

375941

DX39B
Spliceosome RNA helicase DDX39B

2

3

High-throughput

0.584

High

375858

PCNA
Proliferating cell nuclear antigen

1

2

Small-scale

0.578

High

375841

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

4

High-throughput

0.576

High

375877

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

5

High-throughput

0.576

High

375949

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

5

High-throughput

0.576

High

375874

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.576

High

375954

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

3

High-throughput

0.571

High

375843

IFNA4
Interferon alpha-4

1

0

High-throughput

0.549

High

375914

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.541

High

376005

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

1

High-throughput

0.541

High

170203

TIF1A
Transcription intermediary factor 1-alpha

1

1

High-throughput

0.536

High

375853

HS90B
Heat shock protein HSP 90-beta

1

2

Small-scale

0.536

High

375869

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

375903

KI67
Proliferation marker protein Ki-67

1

2

High-throughput

0.536

High

375938

CUL2
Cullin-2

1

3

High-throughput

0.536

High

375940

CUL4B
Cullin-4B

1

3

High-throughput

0.536

High

375948

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.536

High

376020

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

1

High-throughput

0.536

High

375850

ADRB2
Beta-2 adrenergic receptor

1

0

Small-scale

0.529

High

375993

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

375900

CCNF
Cyclin-F

1

1

High-throughput

0.515

High

376029

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

High-throughput

0.515

High

128395

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.513

High

146791

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.513

High

362662

FINC
Fibronectin

1

0

High-throughput

0.513

High

375871

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

375878

RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1

1

0

High-throughput

0.513

High

375893

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.513

High

375902

RAD52
DNA repair protein RAD52 homolog

1

0

Small-scale

0.513

High

375944

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

375984

NICA
Nicastrin

1

0

High-throughput

0.513

High

375994

DRC1
Dynein regulatory complex protein 1

1

0

High-throughput

0.513

High

375899

MLH1
DNA mismatch repair protein Mlh1

1

2

Small-scale

0.508

High

375951

HSPB2
Heat shock protein beta-2

1

2

High-throughput

0.508

High

174535

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

375927

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.501

High

376002

OSB10
Oxysterol-binding protein-related protein 10

1

0

High-throughput

0.493

High

132281

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.486

High

375973

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.486

High

375896

VATE1
V-type proton ATPase subunit E 1

1

2

Small-scale

0.481

High

375988

TRI63
E3 ubiquitin-protein ligase TRIM63

1

2

Small-scale

0.481

High

375999

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

Small-scale

0.481

High

375996

CYH2
Cytohesin-2

1

0

Small-scale

0.480

High

376000

MYOC
Myocilin

1

0

Small-scale

0.480

High

282463

RNF8
E3 ubiquitin-protein ligase RNF8

1

1

High-throughput

0.479

High

294250

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

301523

TRI37
E3 ubiquitin-protein ligase TRIM37

1

2

High-throughput

0.479

High

302765

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

373485

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

375840

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.479

High

375851

HS90A
Heat shock protein HSP 90-alpha

1

2

Small-scale

0.479

High

375854

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.479

High

375859

KCRB
Creatine kinase B-type

1

1

High-throughput

0.479

High

375862

ITA4
Integrin alpha-4

1

2

High-throughput

0.479

High

375864

ENPL
Endoplasmin

1

2

High-throughput

0.479

High

375865

PLAK
Junction plakoglobin

1

1

High-throughput

0.479

High

375866

BRAF
Serine/threonine-protein kinase B-raf

1

2

High-throughput

0.479

High

375870

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

375872

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.479

High

375873

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

375880

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.479

High

375885

CALR
Calreticulin

1

1

High-throughput

0.479

High

375886

PML
Protein PML

1

2

High-throughput

0.479

High

375889

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

Small-scale

0.479

High

375890

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

375892

MSX2
Homeobox protein MSX-2

1

1

High-throughput

0.479

High

375894

FUS
RNA-binding protein FUS

1

2

High-throughput

0.479

High

375897

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.479

High

375898

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

375905

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

375906

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.479

High

375908

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.479

High

375910

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

375912

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

2

High-throughput

0.479

High

375913

ATX3
Ataxin-3

1

1

High-throughput

0.479

High

375921

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.479

High

375924

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

5

Small-scale

0.479

High

375934

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

375936

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

375937

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

375942

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

2

High-throughput

0.479

High

375946

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

375953

CEP78
Centrosomal protein of 78 kDa

1

1

High-throughput

0.479

High

375955

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

375956

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

375959

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.479

High

375962

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

1

High-throughput

0.479

High

375965

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

375966

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

375969

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.479

High

375972

SLX4
Structure-specific endonuclease subunit SLX4

1

1

High-throughput

0.479

High

375976

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

375979

FLCN
Folliculin

1

1

Small-scale

0.479

High

375980

JOS2
Josephin-2

1

1

Small-scale

0.479

High

375981

RIN3
Ras and Rab interactor 3

1

1

High-throughput

0.479

High

375985

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

375986

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

375989

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

376001

MEP50
Methylosome protein WDR77

1

1

High-throughput

0.479

High

376003

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

376004

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

376008

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

1

Small-scale

0.479

High

376012

MT21D
Protein N-lysine methyltransferase METTL21D

1

1

High-throughput

0.479

High

376013

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

1

High-throughput

0.479

High

376021

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

3

High-throughput

0.479

High

376022

HDAC6
Histone deacetylase 6

1

1

High-throughput

0.479

High

376024

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

376025

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

376026

HDAC5
Histone deacetylase 5

1

1

High-throughput

0.479

High

376027

FND3A
Fibronectin type-III domain-containing protein 3A

1

2

High-throughput

0.479

High

376030

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.479

High

173333

S22A1
Solute carrier family 22 member 1

1

0

Small-scale

0.460

High

176527

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.460

High

375974

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.460

High

376023

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.460

High

119070

LEG9
Galectin-9

1

0

High-throughput

0.458

High

165902

PER2
Period circadian protein homolog 2

1

0

Small-scale

0.458

High

197177

SERA
D-3-phosphoglycerate dehydrogenase

1

0

Small-scale

0.458

High

204592

E41L2
Band 4.1-like protein 2

1

0

High-throughput

0.458

High

214022

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

233807

HBP1
HMG box-containing protein 1

1

0

High-throughput

0.458

High

298037

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

314190

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.458

High

345650

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

375852

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

0

Small-scale

0.458

High

375857

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

375860

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

375867

GLNA
Glutamine synthetase

1

0

High-throughput

0.458

High

375868

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

375875

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

375876

RAB4A
Ras-related protein Rab-4A

1

0

High-throughput

0.458

High

375879

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.458

High

375881

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

375882

MT3
Metallothionein-3

1

0

Small-scale

0.458

High

375883

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.458

High

375884

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

375887

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

375888

PDIA3
Protein disulfide-isomerase A3

1

0

High-throughput

0.458

High

375895

TRI23
E3 ubiquitin-protein ligase TRIM23

1

0

High-throughput

0.458

High

375904

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.458

High

375907

CD151
CD151 antigen

1

0

High-throughput

0.458

High

375911

DNLI4
DNA ligase 4

1

0

High-throughput

0.458

High

375915

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.458

High

375918

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

375919

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

375920

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

375923

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

375926

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

375928

VIGLN
Vigilin

1

0

High-throughput

0.458

High

375929

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

375930

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

375931

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

375932

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

375933

ZP4
Zona pellucida sperm-binding protein 4

1

0

Small-scale

0.458

High

375935

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

375943

RBM39
RNA-binding protein 39

1

0

High-throughput

0.458

High

375945

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

375947

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

375950

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

375952

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.458

High

375958

CDC73
Parafibromin

1

0

High-throughput

0.458

High

375960

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

375967

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

375970

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

375975

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

375978

LS14A
Protein LSM14 homolog A

1

0

High-throughput

0.458

High

375982

DJB14
DnaJ homolog subfamily B member 14

1

0

High-throughput

0.458

High

375987

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.458

High

375995

RANB9
Ran-binding protein 9

1

0

Small-scale

0.458

High

375998

NECD
Necdin

1

0

High-throughput

0.458

High

376006

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.458

High

376009

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.458

High

376010

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

376014

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

376016

NGB
Neuroglobin

1

0

High-throughput

0.458

High

376017

ANLN
Anillin

1

0

High-throughput

0.458

High

376018

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

358946

CRYAB
Alpha-crystallin B chain

1

2

High-throughput

0.457

High

173806

MK13
Mitogen-activated protein kinase 13

1

2

Small-scale

0.445

High

375846

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

375848

PRGR
Progesterone receptor

1

1

Small-scale

0.445

High

375957

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.445

High

375847

AP2A
Transcription factor AP-2-alpha

1

0

High-throughput

0.438

High

375992

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

225457

PCDH7
Protocadherin-7

1

1

High-throughput

0.437

High

375842

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

375963

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

375971

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

376011

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

275361

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.426

High

330803

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

375839

PRIO
Major prion protein

1

0

Small-scale

0.426

High

375916

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

375922

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.426

High

375961

CLC4G
C-type lectin domain family 4 member G

1

0

Small-scale

0.426

High

375990

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

375997

ZBT18
Zinc finger and BTB domain-containing protein 18

1

0

High-throughput

0.426

High

376007

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

375909

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.408

High

99538

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

159314

PLD2
Phospholipase D2

1

0

Small-scale

0.292

High

375977

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

0

High-throughput

0.282

High

177572

BCAT2
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

High-throughput

0.251

Low

375891

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

375964

KCTD9
BTB/POZ domain-containing protein KCTD9

1

0

High-throughput

0.249

Low

375983

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.249

Low

375991

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

376019

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

376028

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

375917

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024