Protein: EI2BD
Translation initiation factor eIF2B subunit delta (eIF2B GDP-GTP exchange factor subunit delta)

Gene: EI2BD, EIF2B4
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q9UI10

Gene Ontology (top 5):
GO:0001541 - ovarian follicle development
GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834459

EI2BB
Translation initiation factor eIF2B subunit beta

8

15

High-throughput

0.971

High

1051853

EI2BA
Translation initiation factor eIF2B subunit alpha

3

14

High-throughput

0.861

High

1328924

OPN3
Opsin-3

3

4

High-throughput

0.667

High

1354595

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

2

High-throughput

0.667

High

1122065

Q53XC2
Translation initiation factor eIF2B subunit beta

1

15

High-throughput

0.665

High

1025703

EI2BE
Translation initiation factor eIF2B subunit epsilon

3

15

Small-scale

0.660

High

599606

SYT1
Synaptotagmin-1

2

4

High-throughput

0.628

High

1344279

EI2BG
Translation initiation factor eIF2B subunit gamma

1

11

High-throughput

0.618

High

686824

GP183
G-protein coupled receptor 183

3

6

High-throughput

0.609

High

793165

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

9

High-throughput

0.609

High

1205396

STX12
Syntaxin-12

3

2

High-throughput

0.609

High

1298944

NECT4
Nectin-4

3

5

High-throughput

0.609

High

1304620

P2RX4
P2X purinoceptor 4

3

2

High-throughput

0.609

High

1355657

CAH14
Carbonic anhydrase 14

3

2

High-throughput

0.609

High

1355656

FZD10
Frizzled-10

2

0

High-throughput

0.602

High

780278

CCNF
Cyclin-F

2

3

High-throughput

0.601

High

339098

EGFR
Epidermal growth factor receptor

2

4

Small-scale

0.584

High

1281458

FBXW7
F-box/WD repeat-containing protein 7

2

1

Small-scale

0.584

High

409805

GLPB
Glycophorin-B

2

2

High-throughput

0.574

High

600699

EPHA1
Ephrin type-A receptor 1

2

4

High-throughput

0.574

High

1237333

SIGL1
SIGLEC family-like protein 1

2

2

High-throughput

0.574

High

1333291

PACC1
Proton-activated chloride channel

2

1

High-throughput

0.574

High

556533

LEUK
Leukosialin

2

2

High-throughput

0.558

High

856582

EFNB2
Ephrin-B2

2

4

High-throughput

0.558

High

1233347

PNKD
Probable hydrolase PNKD

2

1

High-throughput

0.558

High

133722

NOP56
Nucleolar protein 56

1

2

High-throughput

0.536

High

207123

XRCC3
DNA repair protein XRCC3

1

2

High-throughput

0.536

High

264654

MTX2
Metaxin-2

1

1

High-throughput

0.536

High

454774

TACD2
Tumor-associated calcium signal transducer 2

1

2

High-throughput

0.536

High

529872

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

587050

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

649810

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.536

High

780802

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

6

High-throughput

0.536

High

793665

DCC
Netrin receptor DCC

1

2

Small-scale

0.536

High

873885

IF5
Eukaryotic translation initiation factor 5

1

5

High-throughput

0.536

High

957957

EFNB1
Ephrin-B1

1

4

High-throughput

0.536

High

962441

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.536

High

1166567

BTNL9
Butyrophilin-like protein 9

1

3

High-throughput

0.536

High

1272841

FGF14
Fibroblast growth factor 14

1

1

High-throughput

0.536

High

1334384

CHODL
Chondrolectin

1

2

High-throughput

0.536

High

1355659

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

2

High-throughput

0.536

High

1355660

E41L3
Band 4.1-like protein 3

1

1

High-throughput

0.536

High

344385

ANGT
Angiotensinogen

1

1

High-throughput

0.515

High

345568

FOS
Protein c-Fos

1

3

High-throughput

0.515

High

380346

HG2A
HLA class II histocompatibility antigen gamma chain

1

0

High-throughput

0.513

High

403363

LA
Lupus La protein

1

0

High-throughput

0.513

High

418763

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

1342626

EXOS4
Exosome complex component RRP41

1

0

High-throughput

0.513

High

1355662

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.513

High

420692

LIPL
Lipoprotein lipase

1

0

High-throughput

0.493

High

772199

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

924928

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.493

High

150486

ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3

1

1

High-throughput

0.489

High

172270

GP182
G-protein coupled receptor 182

1

7

High-throughput

0.489

High

238932

TPST2
Protein-tyrosine sulfotransferase 2

1

2

High-throughput

0.489

High

626803

PTAFR
Platelet-activating factor receptor

1

8

High-throughput

0.489

High

639659

TNR5
Tumor necrosis factor receptor superfamily member 5

1

2

High-throughput

0.489

High

644654

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

4

High-throughput

0.489

High

702316

CD70
CD70 antigen

1

1

High-throughput

0.489

High

714931

BTC
Probetacellulin [Cleaved into: Betacellulin

1

2

High-throughput

0.489

High

1031106

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

9

High-throughput

0.489

High

1067647

P2RY6
P2Y purinoceptor 6

1

7

High-throughput

0.489

High

1078238

CD226
CD226 antigen

1

6

High-throughput

0.489

High

1202573

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

2

High-throughput

0.489

High

1233671

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.489

High

1238367

SYT2
Synaptotagmin-2

1

4

High-throughput

0.489

High

1253053

F174A
Membrane protein FAM174A

1

1

High-throughput

0.489

High

1265968

CLC2B
C-type lectin domain family 2 member B

1

4

High-throughput

0.489

High

1303624

SEC62
Translocation protein SEC62

1

2

High-throughput

0.489

High

1326397

DNAI2
Dynein axonemal intermediate chain 2

1

1

High-throughput

0.489

High

1328628

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.489

High

1335804

PCDH9
Protocadherin-9

1

1

High-throughput

0.489

High

1355653

CC018
Uncharacterized protein C3orf18

1

2

High-throughput

0.489

High

1355658

CLC4A
C-type lectin domain family 4 member A

1

1

High-throughput

0.489

High

1355661

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

1

High-throughput

0.489

High

163430

XPO1
Exportin-1

1

6

High-throughput

0.479

High

228998

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

246400

SCN2B
Sodium channel subunit beta-2

1

4

High-throughput

0.479

High

375058

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

669053

PML
Protein PML

1

3

High-throughput

0.479

High

734804

TRI23
E3 ubiquitin-protein ligase TRIM23

1

1

High-throughput

0.479

High

854841

GDIR1
Rho GDP-dissociation inhibitor 1

1

1

High-throughput

0.479

High

921769

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.479

High

959749

VIGLN
Vigilin

1

1

High-throughput

0.479

High

1052794

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

5

High-throughput

0.479

High

1054106

GRB7
Growth factor receptor-bound protein 7

1

1

Small-scale

0.479

High

1064815

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1146933

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.479

High

1148853

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

1172164

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1270509

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.479

High

1284150

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1294114

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

1296112

DNJC1
DnaJ homolog subfamily C member 1

1

1

High-throughput

0.479

High

1331565

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

1354763

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1355663

5MP1
eIF5-mimic protein 1

1

8

High-throughput

0.479

High

348169

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

818570

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

847921

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

1262629

LMO7
LIM domain only protein 7

1

0

High-throughput

0.458

High

1267228

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1310540

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

1342883

DCP1A
mRNA-decapping enzyme 1A

1

0

High-throughput

0.458

High

1343758

ANLN
Anillin

1

0

High-throughput

0.458

High

1345158

DUS22
Dual specificity protein phosphatase 22

1

0

High-throughput

0.458

High

1348889

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1355073

TES
Testin

1

0

High-throughput

0.458

High

1302348

CK5P2
CDK5 regulatory subunit-associated protein 2

1

3

High-throughput

0.445

High

1303830

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.445

High

1355654

AGO1
Protein argonaute-1

1

1

High-throughput

0.445

High

1281718

UBE2F
NEDD8-conjugating enzyme UBE2F

1

0

High-throughput

0.438

High

385677

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

442576

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.437

High

903586

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

1029989

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.437

High

1166046

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1189001

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1222119

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

1243008

MCU
Calcium uniporter protein, mitochondrial

1

2

High-throughput

0.437

High

1269867

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1281796

IGSF8
Immunoglobulin superfamily member 8

1

1

High-throughput

0.437

High

1331113

EMRE
Essential MCU regulator, mitochondrial

1

2

High-throughput

0.437

High

1355655

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

497754

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

99695

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

402591

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

353310

CD4
T-cell surface glycoprotein CD4

2

0

High-throughput

0.328

High

134337

MFNG
Beta-1,3-N-acetylglucosaminyltransferase manic fringe

1

0

High-throughput

0.279

Low

146421

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

0

High-throughput

0.279

Low

872924

ARSF
Arylsulfatase F

1

0

High-throughput

0.279

Low

1295707

M4A4A
Membrane-spanning 4-domains subfamily A member 4A

1

0

High-throughput

0.279

Low

1328933

TSN10
Tetraspanin-10

1

0

High-throughput

0.279

Low

371475

KLKB1
Plasma kallikrein

1

0

High-throughput

0.268

Low

682406

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.268

Low

839387

GATM
Glycine amidinotransferase, mitochondrial

1

0

High-throughput

0.268

Low

352303

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

824510

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024