Protein: ARC1B
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)

Gene: ARC1B, ARPC1B
Organism: Homo sapiens
Interactions: 181
UniProt ID: O15143

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

168764

ARP2
Actin-related protein 2

10

15

Small-scale

0.977

High

168683

ARPC5
Actin-related protein 2/3 complex subunit 5

8

5

Small-scale

0.972

High

168763

ARP3
Actin-related protein 3

9

16

Small-scale

0.972

High

168761

ARPC4
Actin-related protein 2/3 complex subunit 4

7

5

Small-scale

0.968

High

168839

ARP3B
Actin-related protein 3B

6

16

High-throughput

0.947

High

168826

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

5

5

Small-scale

0.930

High

168681

ARPC2
Actin-related protein 2/3 complex subunit 2

10

4

Small-scale

0.758

High

168833

ANLN
Anillin

2

5

High-throughput

0.754

High

168682

ARPC3
Actin-related protein 2/3 complex subunit 3

7

4

Small-scale

0.749

High

168729

RASA1
Ras GTPase-activating protein 1

2

4

High-throughput

0.737

High

168762

ACTB
Actin, cytoplasmic 1

1

11

High-throughput

0.691

High

168775

ACTG
Actin, cytoplasmic 2

1

11

High-throughput

0.691

High

168840

POGK
Pogo transposable element with KRAB domain

3

2

High-throughput

0.667

High

168680

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

15

High-throughput

0.665

High

168835

ASH1L
Histone-lysine N-methyltransferase ASH1L

1

11

High-throughput

0.665

High

168720

CFTR
Cystic fibrosis transmembrane conductance regulator

3

4

High-throughput

0.650

High

168815

NT5C
5'(3')-deoxyribonucleotidase, cytosolic type

3

0

High-throughput

0.638

High

148143

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.618

High

168712

RS17
Small ribosomal subunit protein eS17

1

4

Small-scale

0.618

High

168758

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

12

High-throughput

0.618

High

168765

RL27
Large ribosomal subunit protein eL27

1

1

Small-scale

0.618

High

168773

RL30
Large ribosomal subunit protein eL30

1

3

Small-scale

0.618

High

168797

EZH2
Histone-lysine N-methyltransferase EZH2

1

16

High-throughput

0.618

High

168820

ARC1A
Actin-related protein 2/3 complex subunit 1A

1

17

High-throughput

0.618

High

168822

FBXW7
F-box/WD repeat-containing protein 7

1

17

Small-scale

0.618

High

168828

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

4

High-throughput

0.618

High

168832

MYO10
Unconventional myosin-X

1

5

Small-scale

0.618

High

168846

PKHG1
Pleckstrin homology domain-containing family G member 1

1

4

High-throughput

0.618

High

168847

COR1C
Coronin-1C

1

17

Small-scale

0.618

High

168849

COR2B
Coronin-2B

1

18

Small-scale

0.618

High

126880

WASL
Actin nucleation-promoting factor WASL

2

12

Small-scale

0.611

High

168685

ACTN4
Alpha-actinin-4

2

3

Small-scale

0.611

High

168730

FLNA
Filamin-A

2

15

Small-scale

0.611

High

168799

DREB
Drebrin

2

5

Small-scale

0.611

High

168746

WASP
Actin nucleation-promoting factor WAS

2

11

Small-scale

0.595

High

168699

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

168744

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

2

3

Small-scale

0.584

High

160255

AURKA
Aurora kinase A

1

6

Small-scale

0.578

High

168805

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.575

High

168689

SH3L1
Adapter SH3BGRL

2

1

High-throughput

0.571

High

168803

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

8

Small-scale

0.571

High

168811

ARHGP
Rho guanine nucleotide exchange factor 25

2

4

High-throughput

0.571

High

168777

SRPK2
SRSF protein kinase 2

1

17

High-throughput

0.569

High

168785

PAK1
Serine/threonine-protein kinase PAK 1

1

7

Small-scale

0.561

High

168808

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.553

High

117516

MYO1C
Unconventional myosin-Ic

1

10

High-throughput

0.536

High

168700

RASK
GTPase KRas

1

8

High-throughput

0.536

High

168701

ESR1
Estrogen receptor

1

20

High-throughput

0.536

High

168732

CDK2
Cyclin-dependent kinase 2

1

6

High-throughput

0.536

High

168741

MYH9
Myosin-9

1

3

High-throughput

0.536

High

168747

CRK
Adapter molecule crk

1

4

High-throughput

0.536

High

168750

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.536

High

168751

CAPZB
F-actin-capping protein subunit beta

1

7

High-throughput

0.536

High

168757

DAPK1
Death-associated protein kinase 1

1

3

High-throughput

0.536

High

168759

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

11

High-throughput

0.536

High

168779

CALD1
Caldesmon

1

20

High-throughput

0.536

High

168784

TWF1
Twinfilin-1

1

2

High-throughput

0.536

High

168792

SRC8
Src substrate cortactin

1

9

High-throughput

0.536

High

168810

PIM3
Serine/threonine-protein kinase pim-3

1

7

High-throughput

0.536

High

168812

SYNPO
Synaptopodin

1

11

High-throughput

0.536

High

168818

MY18A
Unconventional myosin-XVIIIa

1

7

High-throughput

0.536

High

168825

MYO19
Unconventional myosin-XIX

1

5

High-throughput

0.536

High

168834

MYO5C
Unconventional myosin-Vc

1

2

High-throughput

0.536

High

168841

STK26
Serine/threonine-protein kinase 26

1

9

High-throughput

0.536

High

168844

LIMA1
LIM domain and actin-binding protein 1

1

2

High-throughput

0.536

High

168802

Q5JYA6
PLEKHG1

1

4

High-throughput

0.514

High

168791

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

168703

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

168752

MAOX
NADP-dependent malic enzyme

1

0

High-throughput

0.493

High

168690

PRAF3
PRA1 family protein 3

1

2

High-throughput

0.489

High

168813

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

1

High-throughput

0.489

High

127940

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

11

High-throughput

0.479

High

128942

PLK4
Serine/threonine-protein kinase PLK4

1

5

Small-scale

0.479

High

162200

XPO1
Exportin-1

1

14

High-throughput

0.479

High

167764

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

168686

SPOP
Speckle-type POZ protein

1

4

High-throughput

0.479

High

168687

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.479

High

168688

NUPR1
Nuclear protein 1

1

4

High-throughput

0.479

High

168691

SRBS2
Sorbin and SH3 domain-containing protein 2

1

10

Small-scale

0.479

High

168692

TRI37
E3 ubiquitin-protein ligase TRIM37

1

11

High-throughput

0.479

High

168693

UBR5
E3 ubiquitin-protein ligase UBR5

1

6

Small-scale

0.479

High

168694

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

10

High-throughput

0.479

High

168696

LDHA
L-lactate dehydrogenase A chain

1

1

Small-scale

0.479

High

168697

A1AT
Alpha-1-antitrypsin

1

6

Small-scale

0.479

High

168698

AACT
Alpha-1-antichymotrypsin

1

6

Small-scale

0.479

High

168704

ADT2
ADP/ATP translocase 2

1

4

Small-scale

0.479

High

168705

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

5

Small-scale

0.479

High

168706

RLA2
Large ribosomal subunit protein P2

1

4

Small-scale

0.479

High

168707

TETN
Tetranectin

1

2

Small-scale

0.479

High

168708

K1C18
Keratin, type I cytoskeletal 18

1

6

Small-scale

0.479

High

168709

K2C8
Keratin, type II cytoskeletal 8

1

4

Small-scale

0.479

High

168711

TPM2
Tropomyosin beta chain

1

1

Small-scale

0.479

High

168713

ANXA5
Annexin A5

1

1

Small-scale

0.479

High

168714

LEG1
Galectin-1

1

4

Small-scale

0.479

High

168715

PARP1
Poly [ADP-ribose] polymerase 1

1

7

Small-scale

0.479

High

168717

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.479

High

168718

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

Small-scale

0.479

High

168719

KCRB
Creatine kinase B-type

1

1

Small-scale

0.479

High

168721

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

168722

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

Small-scale

0.479

High

168723

H12
Histone H1.2

1

7

Small-scale

0.479

High

168724

YBOX3
Y-box-binding protein 3

1

3

Small-scale

0.479

High

168725

NUCL
Nucleolin

1

5

Small-scale

0.479

High

168727

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

168728

PSB1
Proteasome subunit beta type-1

1

1

Small-scale

0.479

High

168731

TBG1
Tubulin gamma-1 chain

1

18

Small-scale

0.479

High

168733

U2AF2
Splicing factor U2AF 65 kDa subunit

1

9

High-throughput

0.479

High

168734

RL13
Large ribosomal subunit protein eL13

1

2

Small-scale

0.479

High

168735

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

168736

MAP4
Microtubule-associated protein 4

1

9

Small-scale

0.479

High

168737

TEAD1
Transcriptional enhancer factor TEF-1

1

1

Small-scale

0.479

High

168738

RL12
Large ribosomal subunit protein uL11

1

3

Small-scale

0.479

High

168742

MYH10
Myosin-10

1

3

Small-scale

0.479

High

168743

SOX3
Transcription factor SOX-3

1

20

Small-scale

0.479

High

168745

RL35
Large ribosomal subunit protein uL29

1

1

Small-scale

0.479

High

168748

RL21
Large ribosomal subunit protein eL21

1

1

Small-scale

0.479

High

168749

RL28
Large ribosomal subunit protein eL28

1

1

Small-scale

0.479

High

168755

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

18

Small-scale

0.479

High

168756

HMGA2
High mobility group protein HMGI-C

1

1

Small-scale

0.479

High

168760

RAB25
Ras-related protein Rab-25

1

5

High-throughput

0.479

High

168766

RS7
Small ribosomal subunit protein eS7

1

4

Small-scale

0.479

High

168767

RS8
Small ribosomal subunit protein eS8

1

5

Small-scale

0.479

High

168768

RS23
Small ribosomal subunit protein uS12

1

2

Small-scale

0.479

High

168769

RS29
Small ribosomal subunit protein uS14

1

1

Small-scale

0.479

High

168770

RS11
Small ribosomal subunit protein uS17

1

4

Small-scale

0.479

High

168771

RL23A
Large ribosomal subunit protein uL23

1

4

Small-scale

0.479

High

168772

RS15
Small ribosomal subunit protein uS19

1

3

Small-scale

0.479

High

168774

RL31
Large ribosomal subunit protein eL31

1

2

Small-scale

0.479

High

168776

YBOX1
Y-box-binding protein 1

1

3

Small-scale

0.479

High

168778

RL24
Large ribosomal subunit protein eL24

1

2

Small-scale

0.479

High

168780

RL18
Large ribosomal subunit protein eL18

1

3

Small-scale

0.479

High

168781

ZO1
Tight junction protein ZO-1

1

4

Small-scale

0.479

High

168782

SRSF1
Serine/arginine-rich splicing factor 1

1

11

Small-scale

0.479

High

168786

TIF1B
Transcription intermediary factor 1-beta

1

10

High-throughput

0.479

High

168787

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.479

High

168789

SMAD4
Mothers against decapentaplegic homolog 4

1

4

High-throughput

0.479

High

168790

PKP1
Plakophilin-1

1

8

Small-scale

0.479

High

168793

NC2A
Dr1-associated corepressor

1

2

Small-scale

0.479

High

168794

TNIP1
TNFAIP3-interacting protein 1

1

9

High-throughput

0.479

High

168795

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

168796

ELAV1
ELAV-like protein 1

1

3

Small-scale

0.479

High

168800

IF16
Gamma-interferon-inducible protein 16

1

2

Small-scale

0.479

High

168801

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

11

High-throughput

0.479

High

168809

H2AV
Histone H2A.V

1

9

Small-scale

0.479

High

168814

NHLC2
NHL repeat-containing protein 2

1

2

High-throughput

0.479

High

168817

H1X
Histone H1.10

1

2

Small-scale

0.479

High

168819

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

168821

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

168829

SIK2
Serine/threonine-protein kinase SIK2

1

3

Small-scale

0.479

High

168831

NMRL1
NmrA-like family domain-containing protein 1

1

3

High-throughput

0.479

High

168836

NDE1
Nuclear distribution protein nudE homolog 1

1

12

Small-scale

0.479

High

168842

HDAC6
Histone deacetylase 6

1

20

High-throughput

0.479

High

168843

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

168845

TBK1
Serine/threonine-protein kinase TBK1

1

4

High-throughput

0.479

High

168848

MAFF
Transcription factor MafF

1

2

Small-scale

0.479

High

168710

PROF1
Profilin-1

1

0

Small-scale

0.458

High

168716

PPGB
Lysosomal protective protein

1

0

Small-scale

0.458

High

168798

ECM1
Extracellular matrix protein 1

1

0

Small-scale

0.458

High

168838

IL36G
Interleukin-36 gamma

1

0

Small-scale

0.458

High

168695

PAK4
Serine/threonine-protein kinase PAK 4

1

6

High-throughput

0.445

High

168739

BMI1
Polycomb complex protein BMI-1

1

11

High-throughput

0.445

High

168788

CTBP1
C-terminal-binding protein 1

1

6

High-throughput

0.445

High

168702

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.437

High

168726

PO3F2
POU domain, class 3, transcription factor 2

1

5

Small-scale

0.437

High

168740

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

168753

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.437

High

168783

CGNL1
Cingulin-like protein 1

1

3

Small-scale

0.437

High

168816

CHUR
Protein Churchill

1

1

High-throughput

0.437

High

168823

EFHD2
EF-hand domain-containing protein D2

1

4

Small-scale

0.437

High

168850

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

8

Small-scale

0.437

High

168754

CEBPA
CCAAT/enhancer-binding protein alpha

1

11

High-throughput

0.408

High

168804

LITD1
LINE-1 type transposase domain-containing protein 1

1

2

High-throughput

0.407

High

168806

CLC4G
C-type lectin domain family 4 member G

1

2

Small-scale

0.407

High

168824

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.279

Low

168827

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

99728

F227A
Protein FAM227A

1

0

High-throughput

0.269

Low

168830

UBTD1
Ubiquitin domain-containing protein 1

1

0

High-throughput

0.269

Low

168684

ADCY6
Adenylate cyclase type 6

1

0

Small-scale

0.249

Low

168807

CA122
Uncharacterized protein C1orf122

1

0

Small-scale

0.249

Low

168837

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024