Protein: PPIA
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) (SP18) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]

Gene: PPIA
Organism: Mus musculus
Interactions: 35
UniProt ID: P17742

Gene Ontology (top 5):
GO:0000413 - protein peptidyl-prolyl isomerization
GO:0001666 - response to hypoxia
GO:0001933 - negative regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

570757

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

3

3

High-throughput

0.656

High

570761

DLG4
Disks large homolog 4

3

1

High-throughput

0.656

High

570753

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

1

High-throughput

0.536

High

570781

HOME1
Homer protein homolog 1

1

4

High-throughput

0.536

High

570780

MBD2
Methyl-CpG-binding domain protein 2

1

0

Small-scale

0.480

High

140223

HDAC1
Histone deacetylase 1

1

6

Small-scale

0.479

High

371541

CFAD
Complement factor D

1

2

High-throughput

0.479

High

570754

STING
Stimulator of interferon genes protein

1

3

High-throughput

0.479

High

570755

CDKL5
Cyclin-dependent kinase-like 5

1

6

High-throughput

0.479

High

570756

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

2

High-throughput

0.479

High

570758

SC6A4
Sodium-dependent serotonin transporter

1

1

High-throughput

0.479

High

570762

TFE3
Transcription factor E3

1

5

High-throughput

0.479

High

570763

RIGI
Antiviral innate immune response receptor RIG-I

1

10

Small-scale

0.479

High

570766

WDTC1
WD and tetratricopeptide repeats protein 1

1

6

High-throughput

0.479

High

570769

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.479

High

570772

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.479

High

570773

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

7

High-throughput

0.479

High

570775

EED
Polycomb protein EED

1

9

High-throughput

0.479

High

570776

RHEB
GTP-binding protein Rheb

1

1

High-throughput

0.479

High

570779

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

2

Small-scale

0.479

High

570765

ERBIN
Erbin

1

0

High-throughput

0.458

High

570770

CNOT3
CCR4-NOT transcription complex subunit 3

1

0

High-throughput

0.458

High

139813

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.445

High

437599

SODC
Superoxide dismutase [Cu-Zn]

1

4

High-throughput

0.445

High

570759

VDAC1
Voltage-dependent anion-selective channel protein 1

1

2

High-throughput

0.445

High

570767

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

4

High-throughput

0.445

High

570771

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

2

High-throughput

0.445

High

570778

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.445

High

99908

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

2

High-throughput

0.437

High

570774

MAVS
Mitochondrial antiviral-signaling protein

1

2

Small-scale

0.437

High

570777

CNTP2
Contactin-associated protein-like 2

1

2

High-throughput

0.437

High

570760

SOAT1
Sterol O-acyltransferase 1

1

2

High-throughput

0.407

High

570768

COX15
Heme A synthase COX15

1

1

High-throughput

0.407

High

291557

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.249

Low

570764

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024