Protein: NPM
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)

Gene: NPM, Npm1
Organism: Mus musculus
Interactions: 63
UniProt ID: Q61937

Gene Ontology (top 5):
GO:0000054 - ribosomal subunit export from nucleus
GO:0000055 - ribosomal large subunit export from nucleus
GO:0000056 - ribosomal small subunit export from nucleus
GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001558 - regulation of cell growth

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1143206

NPM3
Nucleoplasmin-3

1

6

Small-scale

0.653

High

815150

RL5
Large ribosomal subunit protein uL18

2

2

Small-scale

0.584

High

1143203

FBXW7
F-box/WD repeat-containing protein 7

1

5

Small-scale

0.561

High

1142833

FXR1
RNA-binding protein FXR1

1

2

High-throughput

0.536

High

956331

CDK2
Cyclin-dependent kinase 2

1

3

Small-scale

0.501

High

99992

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

2

High-throughput

0.479

High

139413

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.479

High

250453

DHX9
ATP-dependent RNA helicase A

1

5

Small-scale

0.479

High

291878

PARP2
Poly [ADP-ribose] polymerase 2

1

1

Small-scale

0.479

High

348429

MYC
Myc proto-oncogene protein

1

5

Small-scale

0.479

High

356863

P53
Cellular tumor antigen p53

1

1

Small-scale

0.479

High

449428

NUCL
Nucleolin

1

3

Small-scale

0.479

High

535709

RL7
Large ribosomal subunit protein uL30

1

3

Small-scale

0.479

High

581238

RL13A
Large ribosomal subunit protein uL13

1

2

Small-scale

0.479

High

589633

VIME
Vimentin

1

1

Small-scale

0.479

High

655956

BRAF
Serine/threonine-protein kinase B-raf

1

5

High-throughput

0.479

High

822740

BRCA1
Breast cancer type 1 susceptibility protein homolog

1

5

Small-scale

0.479

High

825784

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

5

Small-scale

0.479

High

885400

EF2
Elongation factor 2

1

2

Small-scale

0.479

High

899902

RL27
Large ribosomal subunit protein eL27

1

2

Small-scale

0.479

High

905795

RS7
Small ribosomal subunit protein eS7

1

1

Small-scale

0.479

High

917007

RS6
Small ribosomal subunit protein eS6

1

2

Small-scale

0.479

High

922777

RS3
Small ribosomal subunit protein uS3

1

1

Small-scale

0.479

High

932083

RL22
Large ribosomal subunit protein eL22

1

2

Small-scale

0.479

High

936563

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

6

Small-scale

0.479

High

936585

ROCK2
Rho-associated protein kinase 2

1

4

Small-scale

0.479

High

956282

RS3A
Small ribosomal subunit protein eS1

1

4

Small-scale

0.479

High

956511

RS5
Small ribosomal subunit protein uS7

1

1

Small-scale

0.479

High

978114

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

7

Small-scale

0.479

High

1103182

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog

1

2

Small-scale

0.479

High

1115937

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

5

High-throughput

0.479

High

1143190

NUP62
Nuclear pore glycoprotein p62

1

2

Small-scale

0.479

High

1143191

TFE3
Transcription factor E3

1

2

High-throughput

0.479

High

1143194

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

3

Small-scale

0.479

High

1143198

FACD2
Fanconi anemia group D2 protein homolog

1

1

High-throughput

0.479

High

1143199

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

1

Small-scale

0.479

High

1143200

MT21E
Protein-lysine methyltransferase METTL21E

1

1

High-throughput

0.479

High

1143204

DDX1
ATP-dependent RNA helicase DDX1

1

3

Small-scale

0.479

High

1143205

EED
Polycomb protein EED

1

8

High-throughput

0.479

High

1143207

CNTP2
Contactin-associated protein-like 2

1

1

High-throughput

0.479

High

1143209

RL4
Large ribosomal subunit protein uL4

1

2

Small-scale

0.479

High

1143210

NUP50
Nuclear pore complex protein Nup50

1

1

Small-scale

0.479

High

1143211

CAF1A
Chromatin assembly factor 1 subunit A

1

3

High-throughput

0.479

High

1143212

FZR1
Fizzy-related protein homolog

1

8

High-throughput

0.479

High

1143213

MECP2
Methyl-CpG-binding protein 2

1

2

Small-scale

0.479

High

550213

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.458

High

868993

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

956607

RGS14
Regulator of G-protein signaling 14

1

0

High-throughput

0.458

High

1110714

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

1143192

ARF
Tumor suppressor ARF

1

0

Small-scale

0.458

High

1143193

BRSK2
Serine/threonine-protein kinase BRSK2

1

0

High-throughput

0.458

High

1143195

NEB2
Neurabin-2

1

0

High-throughput

0.458

High

1143197

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

920128

RS15
Small ribosomal subunit protein uS19

1

2

Small-scale

0.457

High

923894

YBOX1
Y-box-binding protein 1

1

4

Small-scale

0.457

High

1143196

RS27
Small ribosomal subunit protein eS27

1

2

Small-scale

0.457

High

1143201

FTM
Protein fantom

1

2

High-throughput

0.445

High

371936

CFAD
Complement factor D

1

3

High-throughput

0.437

High

558877

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.249

Low

620962

GRIA2
Glutamate receptor 2

1

0

High-throughput

0.249

Low

1143202

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low

1143208

EBPL
Emopamil-binding protein-like

1

0

Small-scale

0.249

Low

1143163

GPAN1
G patch domain and ankyrin repeat-containing protein 1

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024