Protein: MK03
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)

Gene: MK03, Mapk3
Organism: Mus musculus
Interactions: 28
UniProt ID: Q63844

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001784 - phosphotyrosine residue binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1142162

KSR1
Kinase suppressor of Ras 1

3

13

Small-scale

0.827

High

1143246

PEA15
Astrocytic phosphoprotein PEA-15

1

4

Small-scale

0.724

High

1112584

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

5

High-throughput

0.691

High

1115944

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

9

High-throughput

0.691

High

1144377

SQSTM
Sequestosome-1

1

6

Small-scale

0.691

High

1141388

KLF4
Krueppel-like factor 4

1

8

Small-scale

0.653

High

578264

KS6A3
Ribosomal protein S6 kinase alpha-3

1

20

Small-scale

0.647

High

803846

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

2

Small-scale

0.647

High

432433

HS90A
Heat shock protein HSP 90-alpha

1

19

Small-scale

0.618

High

724171

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

10

Small-scale

0.618

High

1144380

SEGN
Secretagogin

1

9

Small-scale

0.618

High

1144381

DLGP1
Disks large-associated protein 1

2

1

High-throughput

0.611

High

381388

MBP
Myelin basic protein

2

6

Small-scale

0.602

High

786542

STAT3
Signal transducer and activator of transcription 3

2

5

Small-scale

0.602

High

139598

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

20

Small-scale

0.584

High

1144379

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

1

20

Small-scale

0.584

High

554917

KPCE
Protein kinase C epsilon type

1

9

Small-scale

0.575

High

1144378

NANOG
Homeobox protein NANOG

1

2

Small-scale

0.573

High

1143328

DLG4
Disks large homolog 4

2

9

High-throughput

0.571

High

723588

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

3

High-throughput

0.536

High

562980

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

16

Small-scale

0.501

High

785338

ELK1
ETS domain-containing protein Elk-1

1

19

Small-scale

0.501

High

99998

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

8

High-throughput

0.479

High

139656

MAP2
Methionine aminopeptidase 2

1

2

Small-scale

0.479

High

192972

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

5

High-throughput

0.479

High

626869

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

3

Small-scale

0.479

High

963733

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

3

High-throughput

0.479

High

1141562

SC6A4
Sodium-dependent serotonin transporter

1

0

High-throughput

0.458

High


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Last updated: 15 Jul 2024