Protein: ARGI1
Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase)

Gene: ARGI1, ARG1
Organism: Homo sapiens
Interactions: 136
UniProt ID: P05089

Gene Ontology (top 5):
GO:0000050 - urea cycle
GO:0002250 - adaptive immune response
GO:0004053 - arginase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396220

ARGI2
Arginase-2, mitochondrial

2

3

High-throughput

0.789

High

396245

ZIC1
Zinc finger protein ZIC 1

2

0

High-throughput

0.602

High

396244

EZH2
Histone-lysine N-methyltransferase EZH2

2

2

High-throughput

0.601

High

396294

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.586

High

368806

ESR1
Estrogen receptor

2

0

High-throughput

0.576

High

345673

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.571

High

396242

TNIP1
TNFAIP3-interacting protein 1

2

0

High-throughput

0.559

High

396239

GPR18
N-arachidonyl glycine receptor

2

1

High-throughput

0.558

High

396304

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

0

Small-scale

0.537

High

396209

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.536

High

396210

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.536

High

396216

MAX
Protein max

1

1

High-throughput

0.536

High

396222

CBX1
Chromobox protein homolog 1

1

2

High-throughput

0.536

High

396234

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.536

High

396282

PCGF6
Polycomb group RING finger protein 6

1

3

High-throughput

0.536

High

396293

EHF
ETS homologous factor

1

1

High-throughput

0.536

High

396295

WRP73
WD repeat-containing protein WRAP73

1

3

High-throughput

0.536

High

256931

KDM4A
Lysine-specific demethylase 4A

1

0

High-throughput

0.513

High

265583

E2F6
Transcription factor E2F6

1

0

High-throughput

0.513

High

329067

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

351509

ANF
Natriuretic peptides A

1

0

High-throughput

0.513

High

396195

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

0

High-throughput

0.513

High

396200

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

High-throughput

0.513

High

396202

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

396211

ATX1
Ataxin-1

1

0

High-throughput

0.513

High

396212

DSCR6
Protein ripply3

1

0

High-throughput

0.513

High

396213

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.513

High

396218

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.513

High

396226

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

0

High-throughput

0.513

High

396247

VWA3B
von Willebrand factor A domain-containing protein 3B

1

0

High-throughput

0.513

High

396256

APTX
Aprataxin

1

0

High-throughput

0.513

High

396260

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.513

High

396261

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.513

High

396262

UB2J2
Ubiquitin-conjugating enzyme E2 J2

1

0

High-throughput

0.513

High

396266

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

High-throughput

0.513

High

396268

THAP4
Peroxynitrite isomerase THAP4

1

0

High-throughput

0.513

High

396272

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

396280

ATGA1
Autophagy-related protein 101

1

0

High-throughput

0.513

High

396286

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

0

High-throughput

0.513

High

396287

COE2
Transcription factor COE2

1

0

High-throughput

0.513

High

396288

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.513

High

396299

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

396206

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

1

0

High-throughput

0.493

High

396241

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

396215

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

282471

RNF8
E3 ubiquitin-protein ligase RNF8

1

1

High-throughput

0.479

High

396191

PLAK
Junction plakoglobin

1

1

High-throughput

0.479

High

396194

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

396203

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.479

High

396224

DSG1
Desmoglein-1

1

1

High-throughput

0.479

High

396230

RBBP4
Histone-binding protein RBBP4

1

2

High-throughput

0.479

High

396231

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

396240

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

396263

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

396264

POC1B
POC1 centriolar protein homolog B

1

2

High-throughput

0.479

High

396278

RANB9
Ran-binding protein 9

1

1

Small-scale

0.479

High

396281

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

396296

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

396300

FBW1A
F-box/WD repeat-containing protein 1A

1

3

High-throughput

0.479

High

396301

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

1

Small-scale

0.479

High

396199

AL4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

1

0

High-throughput

0.460

High

224266

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

301534

TRI37
E3 ubiquitin-protein ligase TRIM37

1

0

High-throughput

0.458

High

345039

CYTA
Cystatin-A

1

0

High-throughput

0.458

High

385909

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

396188

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

396189

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

396190

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

396192

DESP
Desmoplakin

1

0

High-throughput

0.458

High

396193

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

396196

SPR1B
Cornifin-B

1

0

High-throughput

0.458

High

396197

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.458

High

396198

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

396201

CASPE
Caspase-14

1

0

High-throughput

0.458

High

396205

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

396208

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

396217

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

396219

1433Z
14-3-3 protein zeta/delta

1

0

Small-scale

0.458

High

396221

DCD
Dermcidin

1

0

High-throughput

0.458

High

396223

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

396225

K1C17
Keratin, type I cytoskeletal 17

1

0

High-throughput

0.458

High

396227

SRSF1
Serine/arginine-rich splicing factor 1

1

0

High-throughput

0.458

High

396228

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.458

High

396233

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

396236

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

396237

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.458

High

396238

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

0

High-throughput

0.458

High

396243

CDSN
Corneodesmosin

1

0

High-throughput

0.458

High

396246

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

396248

FILA2
Filaggrin-2

1

0

High-throughput

0.458

High

396250

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.458

High

396251

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.458

High

396253

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

396257

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

396267

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.458

High

396269

RBP56
TATA-binding protein-associated factor 2N

1

0

High-throughput

0.458

High

396273

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

Small-scale

0.458

High

396277

SPB12
Serpin B12

1

0

High-throughput

0.458

High

396283

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

396285

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

396290

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

396291

ANLN
Anillin

1

0

High-throughput

0.458

High

396297

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.458

High

396298

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

396303

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

305892

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

1

High-throughput

0.445

High

396214

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

1

High-throughput

0.445

High

396232

TRAF2
TNF receptor-associated factor 2

1

1

High-throughput

0.445

High

396270

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.445

High

396254

WDR82
WD repeat-containing protein 82

1

2

High-throughput

0.437

High

396292

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

396235

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.426

High

396249

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

396275

MITOK
Mitochondrial potassium channel

3

0

High-throughput

0.347

High

209303

TSN6
Tetraspanin-6

1

0

High-throughput

0.279

Low

237640

SEP15
Selenoprotein F

1

0

High-throughput

0.279

Low

303626

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

396207

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

396271

PIGT
GPI transamidase component PIG-T

1

0

High-throughput

0.279

Low

396274

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

396276

CABS1
Calcium-binding and spermatid-specific protein 1

1

0

High-throughput

0.279

Low

396279

SH23A
SH2 domain-containing protein 3A

1

0

High-throughput

0.279

Low

396289

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

396302

FCF1
rRNA-processing protein FCF1 homolog

1

0

High-throughput

0.279

Low

279401

FLOT1
Flotillin-1

1

0

Small-scale

0.275

Low

396255

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

0

High-throughput

0.269

Low

100381

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

384084

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

396204

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

396229

DSC1
Desmocollin-1

1

0

High-throughput

0.249

Low

396252

KPLCE
Protein KPLCE

1

0

High-throughput

0.249

Low

396258

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.249

Low

396259

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

396265

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.249

Low

396284

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.249

Low

239702

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024