Protein: PYGB
Glycogen phosphorylase, brain form (EC 2.4.1.1)

Gene: PYGB
Organism: Homo sapiens
Interactions: 101
UniProt ID: P11216

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005980 - glycogen catabolic process
GO:0008184 - glycogen phosphorylase activity
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

417480

PYGL
Glycogen phosphorylase, liver form

5

5

High-throughput

0.940

High

506148

PYGM
Glycogen phosphorylase, muscle form

3

5

High-throughput

0.858

High

506147

PYGB
Glycogen phosphorylase, brain form

1

5

High-throughput

0.698

High

307582

STBD1
Starch-binding domain-containing protein 1

3

2

High-throughput

0.667

High

506156

NTF3
Neurotrophin-3

2

1

High-throughput

0.611

High

506198

ZFP41
Zinc finger protein 41 homolog

3

1

High-throughput

0.609

High

506191

PPR3B
Protein phosphatase 1 regulatory subunit 3B

3

6

High-throughput

0.607

High

506176

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

2

High-throughput

0.601

High

226360

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

506180

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

1

High-throughput

0.552

High

506192

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

0

High-throughput

0.549

High

180628

GLYG2
Glycogenin-2

1

1

High-throughput

0.536

High

212350

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

1

High-throughput

0.536

High

506152

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

506153

GYS1
Glycogen [starch] synthase, muscle

1

2

High-throughput

0.536

High

506167

GLYG
Glycogenin-1

1

1

High-throughput

0.536

High

506186

PPR3F
Protein phosphatase 1 regulatory subunit 3F

1

2

High-throughput

0.536

High

506202

GASP2
G-protein coupled receptor-associated sorting protein 2

1

2

High-throughput

0.536

High

506209

TX101
Testis-expressed protein 101

1

1

High-throughput

0.536

High

506216

HSPB8
Heat shock protein beta-8

1

2

High-throughput

0.536

High

310377

EPM2A
Laforin

1

0

High-throughput

0.513

High

361811

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

0

High-throughput

0.513

High

398818

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.513

High

506162

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.513

High

506190

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

506204

CERS2
Ceramide synthase 2

1

0

High-throughput

0.513

High

329285

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.493

High

167739

FYB1
FYN-binding protein 1

1

1

High-throughput

0.489

High

319085

PPR3D
Protein phosphatase 1 regulatory subunit 3D

1

6

High-throughput

0.489

High

506169

PMS1
PMS1 protein homolog 1

1

1

High-throughput

0.489

High

506184

CXB7
Gap junction beta-7 protein

1

1

High-throughput

0.489

High

506151

ACTN1
Alpha-actinin-1

1

0

Small-scale

0.480

High

301574

TRI37
E3 ubiquitin-protein ligase TRIM37

1

4

High-throughput

0.479

High

345786

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

452336

PGFRB
Platelet-derived growth factor receptor beta

1

4

High-throughput

0.479

High

456479

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

1

Small-scale

0.479

High

503320

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

506158

PML
Protein PML

1

1

High-throughput

0.479

High

506160

MCM5
DNA replication licensing factor MCM5

1

5

High-throughput

0.479

High

506166

MLH1
DNA mismatch repair protein Mlh1

1

1

High-throughput

0.479

High

506168

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.479

High

506171

H2B1D
Histone H2B type 1-D

1

1

High-throughput

0.479

High

506178

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.479

High

506187

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

506194

RHG24
Rho GTPase-activating protein 24

1

1

High-throughput

0.479

High

506195

EMC5
ER membrane protein complex subunit 5

1

1

High-throughput

0.479

High

506197

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.479

High

506207

H2B1L
Histone H2B type 1-L

1

1

High-throughput

0.479

High

506208

FSD1
Fibronectin type III and SPRY domain-containing protein 1

1

7

High-throughput

0.479

High

506210

SENP3
Sentrin-specific protease 3

1

1

Small-scale

0.479

High

506211

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

506213

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

506215

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

373596

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

417884

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

506150

SKI
Ski oncogene

1

0

Small-scale

0.458

High

506159

UFO
Tyrosine-protein kinase receptor UFO

1

0

High-throughput

0.458

High

506170

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

506174

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

506199

T185A
Transmembrane protein 185A

1

0

High-throughput

0.458

High

239740

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.457

High

120814

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

High-throughput

0.445

High

496169

TAU
Microtubule-associated protein tau

1

10

High-throughput

0.445

High

506172

SMS
Somatostatin

1

1

Small-scale

0.445

High

506217

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

506149

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

100426

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

243845

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.437

High

488879

H14
Histone H1.4

1

1

High-throughput

0.437

High

506154

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

506155

VGFR1
Vascular endothelial growth factor receptor 1

1

3

High-throughput

0.437

High

506157

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

506161

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

506164

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

3

High-throughput

0.437

High

506173

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

506183

FBX42
F-box only protein 42

1

1

High-throughput

0.437

High

506200

COP1
E3 ubiquitin-protein ligase COP1

1

1

High-throughput

0.437

High

506201

DPF3
Zinc finger protein DPF3

1

1

Small-scale

0.437

High

377897

PRIO
Major prion protein

1

0

High-throughput

0.426

High

506177

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

388851

CP1A1
Cytochrome P450 1A1

2

0

High-throughput

0.318

High

323465

NDST3
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

1

0

High-throughput

0.279

Low

506163

PDE6B
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta

1

0

High-throughput

0.279

Low

506175

CD69
Early activation antigen CD69

1

0

High-throughput

0.279

Low

506181

CTSRE
Cation channel sperm-associated auxiliary subunit epsilon

1

0

High-throughput

0.279

Low

506182

KIF24
Kinesin-like protein KIF24

1

0

High-throughput

0.279

Low

506188

CDHR3
Cadherin-related family member 3

1

0

High-throughput

0.279

Low

506193

SUGP1
SURP and G-patch domain-containing protein 1

1

0

High-throughput

0.279

Low

506203

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.279

Low

506212

BIN3
Bridging integrator 3

1

0

High-throughput

0.279

Low

384166

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

506165

DHB3
17-beta-hydroxysteroid dehydrogenase type 3

1

0

High-throughput

0.249

Low

506179

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

506185

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

506189

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

0

Small-scale

0.249

Low

506196

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

0

High-throughput

0.249

Low

506205

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.249

Low

506206

CCNL2
Cyclin-L2

1

0

High-throughput

0.249

Low

506214

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

200485

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024