Protein: KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

Gene: KAP2, PRKAR2A
Organism: Homo sapiens
Interactions: 156
UniProt ID: P13861

Gene Ontology (top 5):
GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

533780

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

8

20

Small-scale

0.969

High

533786

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

6

20

High-throughput

0.950

High

533822

AKP13
A-kinase anchor protein 13

6

6

Small-scale

0.930

High

533795

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

5

20

High-throughput

0.927

High

414708

CDK1
Cyclin-dependent kinase 1

3

3

Small-scale

0.857

High

533819

AKA12
A-kinase anchor protein 12

3

2

Small-scale

0.847

High

533882

AKA7G
A-kinase anchor protein 7 isoform gamma

3

8

Small-scale

0.840

High

533784

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

2

20

High-throughput

0.811

High

533856

AKAP1
A-kinase anchor protein 1, mitochondrial

9

3

Small-scale

0.753

High

533848

AKA28
A-kinase anchor protein 14

6

2

Small-scale

0.738

High

533829

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

8

High-throughput

0.737

High

533787

AKAP5
A-kinase anchor protein 5

6

5

Small-scale

0.731

High

533837

MARE1
Microtubule-associated protein RP/EB family member 1

4

3

Small-scale

0.692

High

533805

KC1D
Casein kinase I isoform delta

1

5

High-throughput

0.691

High

533806

KC1E
Casein kinase I isoform epsilon

1

9

High-throughput

0.691

High

533824

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

3

High-throughput

0.691

High

533838

MK06
Mitogen-activated protein kinase 6

1

7

High-throughput

0.691

High

211290

AKA7A
A-kinase anchor protein 7 isoforms alpha and beta

1

8

High-throughput

0.665

High

496203

TAU
Microtubule-associated protein tau

3

6

Small-scale

0.650

High

533840

AKAP4
A-kinase anchor protein 4

1

10

Small-scale

0.647

High

215575

AKAP8
A-kinase anchor protein 8

3

0

Small-scale

0.646

High

226406

PRKN
E3 ubiquitin-protein ligase parkin

3

9

High-throughput

0.640

High

533884

AKA11
A-kinase anchor protein 11

3

5

Small-scale

0.635

High

196261

PJA2
E3 ubiquitin-protein ligase Praja-2

2

1

Small-scale

0.634

High

533863

CK5P2
CDK5 regulatory subunit-associated protein 2

3

10

Small-scale

0.633

High

533865

AKAP9
A-kinase anchor protein 9

3

7

Small-scale

0.631

High

533813

DYL1
Dynein light chain 1, cytoplasmic

2

3

High-throughput

0.628

High

279999

AKAP3
A-kinase anchor protein 3

2

9

Small-scale

0.625

High

533775

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

18

Small-scale

0.621

High

533779

KPCA
Protein kinase C alpha type

1

9

High-throughput

0.618

High

533807

GSK3B
Glycogen synthase kinase-3 beta

1

6

Small-scale

0.618

High

533808

KCNQ1
Potassium voltage-gated channel subfamily KQT member 1

1

3

Small-scale

0.618

High

503259

MTAP2
Microtubule-associated protein 2

2

7

Small-scale

0.611

High

533830

RAB32
Ras-related protein Rab-32

2

2

Small-scale

0.594

High

533842

MYOME
Myomegalin

2

12

Small-scale

0.576

High

533831

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.575

High

368909

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

533814

RACK1
Small ribosomal subunit protein RACK1

1

4

Small-scale

0.561

High

506862

LAMP1
Lysosome-associated membrane glycoprotein 1

2

0

High-throughput

0.559

High

533887

PLAK2
PALM2-AKAP2 fusion protein

2

4

Small-scale

0.550

High

164768

SC16A
Protein transport protein Sec16A

1

1

High-throughput

0.536

High

272481

OFD1
Centriole and centriolar satellite protein OFD1

1

4

High-throughput

0.536

High

317207

PCNT
Pericentrin

1

6

High-throughput

0.536

High

318920

CEP43
Centrosomal protein 43

1

1

High-throughput

0.536

High

394038

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.536

High

528459

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

533776

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

1

High-throughput

0.536

High

533793

CLIP1
CAP-Gly domain-containing linker protein 1

1

2

High-throughput

0.536

High

533798

HSP74
Heat shock 70 kDa protein 4

1

4

High-throughput

0.536

High

533815

TBB4B
Tubulin beta-4B chain

1

3

High-throughput

0.536

High

533827

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.536

High

533866

TX101
Testis-expressed protein 101

1

1

High-throughput

0.536

High

100442

APRIO
Alternative prion protein

2

2

High-throughput

0.533

High

533891

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

3

Small-scale

0.527

High

533821

MTG8
Protein CBFA2T1

1

2

Small-scale

0.523

High

200366

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.513

High

533817

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

533885

PRDM4
PR domain zinc finger protein 4

1

0

High-throughput

0.513

High

253963

MTG16
Protein CBFA2T3

1

2

Small-scale

0.512

High

174593

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

345298

FOS
Protein c-Fos

1

1

Small-scale

0.481

High

533804

INAR2
Interferon alpha/beta receptor 2

1

0

Small-scale

0.480

High

533854

WASF1
Actin-binding protein WASF1

1

0

Small-scale

0.480

High

120292

RHOD
Rho-related GTP-binding protein RhoD

1

6

High-throughput

0.479

High

129682

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

2

High-throughput

0.479

High

162377

XPO1
Exportin-1

1

5

High-throughput

0.479

High

261950

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.479

High

294322

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

304781

MFN2
Mitofusin-2

1

1

High-throughput

0.479

High

325015

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.479

High

341185

HPT
Haptoglobin

1

1

High-throughput

0.479

High

364516

TRFE
Serotransferrin

1

1

High-throughput

0.479

High

434128

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

4

High-throughput

0.479

High

501625

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

533777

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

533781

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

533782

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

4

High-throughput

0.479

High

533785

CBL
E3 ubiquitin-protein ligase CBL

1

1

High-throughput

0.479

High

533788

CCNE1
G1/S-specific cyclin-E1

1

1

Small-scale

0.479

High

533790

PDE4A
3',5'-cyclic-AMP phosphodiesterase 4A

1

5

Small-scale

0.479

High

533791

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

533792

CCND3
G1/S-specific cyclin-D3

1

2

Small-scale

0.479

High

533794

GCH1
GTP cyclohydrolase 1

1

1

Small-scale

0.479

High

533797

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

533801

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

533802

INGR2
Interferon gamma receptor 2

1

2

Small-scale

0.479

High

533803

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

533810

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

533811

H4
Histone H4

1

1

High-throughput

0.479

High

533812

RAC1
Ras-related C3 botulinum toxin substrate 1

1

4

High-throughput

0.479

High

533816

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.479

High

533820

CAV1
Caveolin-1

1

2

Small-scale

0.479

High

533826

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

533828

CUL3
Cullin-3

1

3

High-throughput

0.479

High

533832

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.479

High

533833

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

2

Small-scale

0.479

High

533835

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.479

High

533844

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

533845

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

533846

MOB3C
MOB kinase activator 3C

1

2

High-throughput

0.479

High

533849

TAXB1
Tax1-binding protein 1

1

4

High-throughput

0.479

High

533850

MIRO2
Mitochondrial Rho GTPase 2

1

8

High-throughput

0.479

High

533853

DPTOR
DEP domain-containing mTOR-interacting protein

1

1

Small-scale

0.479

High

533855

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

533859

DYL2
Dynein light chain 2, cytoplasmic

1

3

High-throughput

0.479

High

533862

SCLT1
Sodium channel and clathrin linker 1

1

4

High-throughput

0.479

High

533864

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.479

High

533867

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

533868

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.479

High

533870

RHOJ
Rho-related GTP-binding protein RhoJ

1

4

High-throughput

0.479

High

533871

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

533873

RHOF
Rho-related GTP-binding protein RhoF

1

5

High-throughput

0.479

High

533875

ANLN
Anillin

1

1

High-throughput

0.479

High

533877

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.479

High

533878

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

533879

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.479

High

533881

MTCH1
Mitochondrial carrier homolog 1

1

4

High-throughput

0.479

High

533883

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

533886

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

2

High-throughput

0.479

High

533888

PTN22
Tyrosine-protein phosphatase non-receptor type 22

1

2

High-throughput

0.479

High

533889

FIS1
Mitochondrial fission 1 protein

1

1

High-throughput

0.479

High

533890

MTCH2
Mitochondrial carrier homolog 2

1

5

High-throughput

0.479

High

430029

PROF1
Profilin-1

1

0

High-throughput

0.458

High

533783

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.458

High

533809

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

533818

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

533839

MIDN
Midnolin

1

0

High-throughput

0.458

High

533843

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

533852

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

533876

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

533880

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

High-throughput

0.458

High

533796

1433S
14-3-3 protein sigma

1

5

Small-scale

0.457

High

377909

PRIO
Major prion protein

1

1

High-throughput

0.445

High

401338

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

483969

CALM2
Calmodulin-2

1

3

High-throughput

0.445

High

484053

CALM3
Calmodulin-3

1

3

High-throughput

0.445

High

533799

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

533851

POC5
Centrosomal protein POC5

1

1

High-throughput

0.445

High

533861

CEP63
Centrosomal protein of 63 kDa

1

4

High-throughput

0.445

High

533869

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

5

High-throughput

0.445

High

533778

H12
Histone H1.2

1

3

High-throughput

0.437

High

533789

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

533825

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.437

High

533834

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.437

High

533836

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

1

High-throughput

0.437

High

533847

MAVS
Mitochondrial antiviral-signaling protein

1

2

High-throughput

0.437

High

533857

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

533858

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.437

High

533872

WDR76
WD repeat-containing protein 76

1

3

High-throughput

0.437

High

533874

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.437

High

533823

AKAP6
A-kinase anchor protein 6

1

4

Small-scale

0.408

High

533860

C170L
Cep170-like protein

1

1

High-throughput

0.407

High

533841

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

2

0

High-throughput

0.316

High

452602

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

533800

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024