Protein: SYT1
Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)

Gene: SYT1
Organism: Homo sapiens
Interactions: 82
UniProt ID: P21579

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0001786 - phosphatidylserine binding
GO:0005509 - calcium ion binding
GO:0005513 - detection of calcium ion
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

129080

SYT5
Synaptotagmin-5

3

17

High-throughput

0.861

High

599585

SYT2
Synaptotagmin-2

2

18

High-throughput

0.811

High

599575

STX1A
Syntaxin-1A

2

8

Small-scale

0.778

High

599595

S10AD
Protein S100-A13

2

0

Small-scale

0.716

High

599558

SNP25
Synaptosomal-associated protein 25

4

8

Small-scale

0.680

High

599551

STX2
Syntaxin-2

1

8

Small-scale

0.647

High

599566

STX4
Syntaxin-4

1

8

Small-scale

0.647

High

599569

STX3
Syntaxin-3

1

8

Small-scale

0.647

High

599576

DGUOK
Deoxyguanosine kinase, mitochondrial

3

0

High-throughput

0.638

High

599602

KTU
Protein kintoun

3

0

High-throughput

0.638

High

599554

EI2BB
Translation initiation factor eIF2B subunit beta

2

4

High-throughput

0.628

High

599561

VLDLR
Very low-density lipoprotein receptor

2

3

High-throughput

0.628

High

599568

EI2BE
Translation initiation factor eIF2B subunit epsilon

2

3

High-throughput

0.628

High

599601

EI2BG
Translation initiation factor eIF2B subunit gamma

2

3

High-throughput

0.628

High

599606

EI2BD
Translation initiation factor eIF2B subunit delta

2

4

High-throughput

0.628

High

399131

FGF1
Fibroblast growth factor 1

1

0

Small-scale

0.614

High

599549

MIP
Lens fiber major intrinsic protein

2

1

High-throughput

0.606

High

599550

HMOX2
Heme oxygenase 2

2

1

High-throughput

0.606

High

599567

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

1

High-throughput

0.606

High

599588

BT2A2
Butyrophilin subfamily 2 member A2

2

2

High-throughput

0.606

High

599596

SNAB
Beta-soluble NSF attachment protein

2

1

High-throughput

0.606

High

599589

STON2
Stonin-2

2

4

Small-scale

0.602

High

599608

RRP7A
Ribosomal RNA-processing protein 7 homolog A

2

0

High-throughput

0.602

High

599611

NEMO
NF-kappa-B essential modulator

1

3

High-throughput

0.594

High

305357

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.580

High

599609

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.580

High

422681

PGK2
Phosphoglycerate kinase 2

2

1

High-throughput

0.574

High

599599

CWC22
Pre-mRNA-splicing factor CWC22 homolog

2

1

High-throughput

0.574

High

560483

TSHR
Thyrotropin receptor

1

0

High-throughput

0.558

High

196730

CYB5B
Cytochrome b5 type B

2

1

High-throughput

0.553

High

124973

CACB4
Voltage-dependent L-type calcium channel subunit beta-4

1

1

Small-scale

0.552

High

599574

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.537

High

155883

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

1

High-throughput

0.536

High

446009

CD63
CD63 antigen

1

1

High-throughput

0.536

High

496296

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.536

High

599562

LRP2
Low-density lipoprotein receptor-related protein 2

1

3

High-throughput

0.536

High

599570

BLMH
Bleomycin hydrolase

1

1

High-throughput

0.536

High

599607

MCTS1
Malignant T-cell-amplified sequence 1

1

1

High-throughput

0.536

High

599586

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.518

High

599552

SDC2
Syndecan-2

1

0

High-throughput

0.513

High

599556

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

599610

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

132287

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

12

Small-scale

0.501

High

599598

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.501

High

599592

RBM18
Probable RNA-binding protein 18

1

1

High-throughput

0.489

High

599590

CBP
CREB-binding protein

1

1

Small-scale

0.481

High

599553

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.480

High

599593

RBM14
RNA-binding protein 14

1

0

Small-scale

0.480

High

384256

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

599555

RB27A
Ras-related protein Rab-27A

1

19

Small-scale

0.479

High

599560

VAMP2
Vesicle-associated membrane protein 2

1

4

Small-scale

0.479

High

599573

RB33A
Ras-related protein Rab-33A

1

5

Small-scale

0.479

High

599577

SV2C
Synaptic vesicle glycoprotein 2C

1

4

Small-scale

0.479

High

599581

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

599582

SV2B
Synaptic vesicle glycoprotein 2B

1

4

Small-scale

0.479

High

599583

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

582062

NUCL
Nucleolin

1

0

High-throughput

0.458

High

235707

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

Small-scale

0.457

High

599557

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

1

1

Small-scale

0.457

High

599564

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.457

High

239777

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

377926

PRIO
Major prion protein

1

1

High-throughput

0.445

High

599563

ANK2
Ankyrin-2

1

1

High-throughput

0.445

High

599571

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

12

High-throughput

0.445

High

100476

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

498388

CMGA
Chromogranin-A

1

1

Small-scale

0.437

High

599600

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

2

High-throughput

0.407

High

118200

HAX1
HCLS1-associated protein X-1

3

0

High-throughput

0.347

High

599603

ARMC1
Armadillo repeat-containing protein 1

3

0

High-throughput

0.347

High

599605

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.347

High

599578

BOREA
Borealin

2

0

High-throughput

0.328

High

599584

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

0

High-throughput

0.316

High

599587

TM254
Transmembrane protein 254

2

0

High-throughput

0.316

High

599591

GIMA5
GTPase IMAP family member 5

2

0

High-throughput

0.316

High

599597

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

599604

TM14C
Transmembrane protein 14C

2

0

High-throughput

0.316

High

599594

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.275

Low

599559

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.249

Low

599565

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.249

Low

599572

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.249

Low

599579

A16L1
Autophagy-related protein 16-1

1

0

Small-scale

0.249

Low

599580

CF015
Uncharacterized protein C6orf15

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024