Protein: SYWC
Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS]

Gene: SYWC, WARS1
Organism: Homo sapiens
Interactions: 78
UniProt ID: P23381

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0004830 - tryptophan-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

616039

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

5

Small-scale

0.647

High

226542

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

397779

ISG15
Ubiquitin-like protein ISG15

2

4

High-throughput

0.584

High

295935

MTA2
Metastasis-associated protein MTA2

2

1

High-throughput

0.571

High

616053

PTN12
Tyrosine-protein phosphatase non-receptor type 12

2

0

High-throughput

0.547

High

616049

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.543

High

616045

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.541

High

616066

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.536

High

616048

DNLI4
DNA ligase 4

1

0

High-throughput

0.529

High

616071

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

571084

EGLN
Endoglin

1

0

High-throughput

0.513

High

616082

DCA13
DDB1- and CUL4-associated factor 13

1

2

High-throughput

0.508

High

616083

DNM3B
DNA

1

1

High-throughput

0.508

High

616043

CADH5
Cadherin-5

1

0

Small-scale

0.505

High

174628

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

394133

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

475343

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

232781

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

4

High-throughput

0.479

High

322193

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

329362

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.479

High

345941

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

384275

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

455093

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.479

High

501689

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.479

High

551962

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

569195

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

607587

NDKB
Nucleoside diphosphate kinase B

1

1

High-throughput

0.479

High

616041

U2AF2
Splicing factor U2AF 65 kDa subunit

1

3

High-throughput

0.479

High

616042

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

616051

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

616052

UBE3A
Ubiquitin-protein ligase E3A

1

3

High-throughput

0.479

High

616054

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

616055

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

616057

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

616060

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.479

High

616062

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

616063

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

616064

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

1

High-throughput

0.479

High

616068

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

616069

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.479

High

616070

OPTN
Optineurin

1

2

High-throughput

0.479

High

616074

NECD
Necdin

1

3

High-throughput

0.479

High

616079

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

616080

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

616081

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

616084

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

616086

FBW1B
F-box/WD repeat-containing protein 11

1

4

High-throughput

0.479

High

616087

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.479

High

616089

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

422348

NFM
Neurofilament medium polypeptide

1

0

High-throughput

0.458

High

616040

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.458

High

616050

CD81
CD81 antigen

1

0

High-throughput

0.458

High

616065

MTMRE
Myotubularin-related protein 14

1

0

High-throughput

0.458

High

616067

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

616073

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

616077

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

616078

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

616085

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.458

High

616088

MTMR7
Myotubularin-related protein 7

1

0

High-throughput

0.458

High

401428

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

496314

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

528559

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.445

High

616058

Q32Q12
Nucleoside diphosphate kinase

1

1

High-throughput

0.445

High

616059

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

616061

Q6IAV4
Cyclin-dependent kinase 2-associated protein

1

0

High-throughput

0.438

High

100485

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

616044

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

616046

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

616056

PTC1
Protein patched homolog 1

1

1

Small-scale

0.437

High

377931

PRIO
Major prion protein

1

0

High-throughput

0.426

High

616072

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.426

High

616047

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.408

High

616076

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.407

High

234475

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.282

High

616075

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

205054

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

259419

NIPS2
Protein NipSnap homolog 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024