Protein: MAP4
Microtubule-associated protein 4 (MAP-4)

Gene: MAP4
Organism: Homo sapiens
Interactions: 226
UniProt ID: P27816

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0003723 - RNA binding
GO:0005198 - structural molecule activity
GO:0005815 - microtubule organizing center
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

496363

TAU
Microtubule-associated protein tau

4

16

High-throughput

0.892

High

653932

YAP1
Transcriptional coactivator YAP1

3

20

Small-scale

0.640

High

369030

ESR1
Estrogen receptor

3

20

High-throughput

0.633

High

427847

CAN1
Calpain-1 catalytic subunit

2

9

High-throughput

0.621

High

262237

ULK1
Serine/threonine-protein kinase ULK1

2

20

Small-scale

0.611

High

501722

BIP
Endoplasmic reticulum chaperone BiP

2

15

High-throughput

0.611

High

654022

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

3

Small-scale

0.584

High

654038

RANB9
Ran-binding protein 9

2

17

Small-scale

0.584

High

592112

RAB5A
Ras-related protein Rab-5A

2

18

High-throughput

0.571

High

654029

OTUB1
Ubiquitin thioesterase OTUB1

2

2

High-throughput

0.571

High

654026

FBXW7
F-box/WD repeat-containing protein 7

1

7

Small-scale

0.561

High

653997

RICTR
Rapamycin-insensitive companion of mTOR

2

0

High-throughput

0.559

High

654060

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

2

0

Small-scale

0.559

High

654034

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

9

High-throughput

0.552

High

654030

NEUL4
Neuralized-like protein 4

2

1

High-throughput

0.549

High

351050

LDLR
Low-density lipoprotein receptor

1

2

High-throughput

0.541

High

447656

ENOG
Gamma-enolase

1

8

High-throughput

0.541

High

653942

TERF1
Telomeric repeat-binding factor 1

1

2

High-throughput

0.541

High

116777

KIF2A
Kinesin-like protein KIF2A

1

10

High-throughput

0.536

High

200503

CP110
Centriolar coiled-coil protein of 110 kDa

1

1

High-throughput

0.536

High

201907

WDR62
WD repeat-containing protein 62

1

9

High-throughput

0.536

High

270579

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

10

High-throughput

0.536

High

311789

TACC2
Transforming acidic coiled-coil-containing protein 2

1

14

High-throughput

0.536

High

319726

HERC2
E3 ubiquitin-protein ligase HERC2

1

12

High-throughput

0.536

High

362848

FINC
Fibronectin

1

10

High-throughput

0.536

High

385842

CPNS1
Calpain small subunit 1

1

11

High-throughput

0.536

High

432562

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

10

High-throughput

0.536

High

653931

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.536

High

653939

NEK4
Serine/threonine-protein kinase Nek4

1

16

High-throughput

0.536

High

653941

BLM
RecQ-like DNA helicase BLM

1

13

High-throughput

0.536

High

653949

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.536

High

653959

RAE1L
mRNA export factor RAE1

1

9

High-throughput

0.536

High

653960

PRKDC
DNA-dependent protein kinase catalytic subunit

1

8

High-throughput

0.536

High

653963

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.536

High

653965

ILF3
Interleukin enhancer-binding factor 3

1

16

High-throughput

0.536

High

653975

EPN4
Clathrin interactor 1

1

10

High-throughput

0.536

High

653977

KIF22
Kinesin-like protein KIF22

1

11

High-throughput

0.536

High

653985

MK06
Mitogen-activated protein kinase 6

1

14

High-throughput

0.536

High

653987

MA7D1
MAP7 domain-containing protein 1

1

20

High-throughput

0.536

High

653989

PDZ11
PDZ domain-containing protein 11

1

17

High-throughput

0.536

High

654011

CKP2L
Cytoskeleton-associated protein 2-like

1

1

High-throughput

0.536

High

654018

MIPT3
TRAF3-interacting protein 1

1

7

Small-scale

0.536

High

654021

CKAP2
Cytoskeleton-associated protein 2

1

1

High-throughput

0.536

High

654035

SPAG5
Sperm-associated antigen 5

1

18

High-throughput

0.536

High

654041

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.536

High

654042

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

3

High-throughput

0.536

High

654043

KIF2C
Kinesin-like protein KIF2C

1

14

High-throughput

0.536

High

654048

TBCD
Tubulin-specific chaperone D

1

1

High-throughput

0.536

High

654056

PKHA5
Pleckstrin homology domain-containing family A member 5

1

18

High-throughput

0.536

High

654064

SLTM
SAFB-like transcription modulator

1

19

High-throughput

0.536

High

654071

RALY
RNA-binding protein Raly

1

5

High-throughput

0.536

High

654075

CP131
Centrosomal protein of 131 kDa

1

10

High-throughput

0.536

High

654084

EPN1
Epsin-1

1

11

High-throughput

0.536

High

243972

BRD4
Bromodomain-containing protein 4

2

10

High-throughput

0.533

High

345991

MYC
Myc proto-oncogene protein

2

11

High-throughput

0.533

High

552003

RFA2
Replication protein A 32 kDa subunit

2

5

High-throughput

0.533

High

650429

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

5

High-throughput

0.533

High

653925

RFA3
Replication protein A 14 kDa subunit

2

3

High-throughput

0.533

High

653971

SNTA1
Alpha-1-syntrophin

1

16

Small-scale

0.527

High

654037

ERBIN
Erbin

1

2

Small-scale

0.527

High

558993

H15
Histone H1.5

1

12

High-throughput

0.515

High

653928

CCNF
Cyclin-F

1

1

High-throughput

0.515

High

653986

MIC60
MICOS complex subunit MIC60

1

4

High-throughput

0.515

High

654081

CHTOP
Chromatin target of PRMT1 protein

1

1

High-throughput

0.515

High

654054

FA83D
Protein FAM83D

1

0

High-throughput

0.513

High

653936

GSK3B
Glycogen synthase kinase-3 beta

1

19

High-throughput

0.508

High

414755

CDK1
Cyclin-dependent kinase 1

1

6

Small-scale

0.501

High

475367

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

17

High-throughput

0.501

High

653950

SUMO2
Small ubiquitin-related modifier 2

1

4

High-throughput

0.501

High

653958

SRPK2
SRSF protein kinase 2

1

18

High-throughput

0.501

High

654032

MARK4
MAP/microtubule affinity-regulating kinase 4

1

11

Small-scale

0.501

High

654063

POTE1
Protection of telomeres protein 1

1

1

High-throughput

0.494

High

157295

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

3

High-throughput

0.489

High

231796

MABP1
Mitogen-activated protein kinase-binding protein 1

1

9

High-throughput

0.489

High

653961

CBX1
Chromobox protein homolog 1

1

4

High-throughput

0.489

High

653973

CUL4A
Cullin-4A

1

10

High-throughput

0.489

High

654013

SPRY3
SPRY domain-containing protein 3

1

14

High-throughput

0.489

High

654014

SLAI1
SLAIN motif-containing protein 1

1

3

High-throughput

0.489

High

654015

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.489

High

654047

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

14

High-throughput

0.489

High

654080

EMC9
ER membrane protein complex subunit 9

1

1

High-throughput

0.489

High

653919

RXRB
Retinoic acid receptor RXR-beta

1

20

High-throughput

0.481

High

653946

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.481

High

653978

NR1I3
Nuclear receptor subfamily 1 group I member 3

1

20

High-throughput

0.481

High

654004

CLAP1
CLIP-associating protein 1

1

9

High-throughput

0.481

High

654039

STRBP
Spermatid perinuclear RNA-binding protein

1

16

High-throughput

0.481

High

654078

NOP58
Nucleolar protein 58

1

1

High-throughput

0.481

High

125172

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

11

High-throughput

0.479

High

168736

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

9

Small-scale

0.479

High

205072

TGON2
Trans-Golgi network integral membrane protein 2

1

18

High-throughput

0.479

High

208243

DCX
Neuronal migration protein doublecortin

1

5

Small-scale

0.479

High

232787

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

10

High-throughput

0.479

High

241456

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.479

High

282537

RNF8
E3 ubiquitin-protein ligase RNF8

1

4

High-throughput

0.479

High

301630

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

322215

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

17

High-throughput

0.479

High

324240

BAG3
BAG family molecular chaperone regulator 3

1

3

High-throughput

0.479

High

337976

EGFR
Epidermal growth factor receptor

1

19

High-throughput

0.479

High

373721

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

10

High-throughput

0.479

High

384314

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.479

High

386146

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

397795

ISG15
Ubiquitin-like protein ISG15

1

16

High-throughput

0.479

High

503487

HSP7C
Heat shock cognate 71 kDa protein

1

10

High-throughput

0.479

High

521739

CADH1
Cadherin-1

1

7

High-throughput

0.479

High

523538

XRCC6
X-ray repair cross-complementing protein 6

1

5

High-throughput

0.479

High

557613

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

580935

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

6

High-throughput

0.479

High

653918

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

8

High-throughput

0.479

High

653920

PML
Protein PML

1

20

High-throughput

0.479

High

653921

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

653922

GRK5
G protein-coupled receptor kinase 5

1

19

High-throughput

0.479

High

653924

PHB1
Prohibitin 1

1

9

High-throughput

0.479

High

653926

SYUA
Alpha-synuclein

1

5

High-throughput

0.479

High

653927

BRCA1
Breast cancer type 1 susceptibility protein

1

9

High-throughput

0.479

High

653929

EPS15
Epidermal growth factor receptor substrate 15

1

6

High-throughput

0.479

High

653938

HDGF
Hepatoma-derived growth factor

1

7

High-throughput

0.479

High

653940

KIF11
Kinesin-like protein KIF11

1

15

High-throughput

0.479

High

653943

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

4

High-throughput

0.479

High

653945

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.479

High

653947

UBC12
NEDD8-conjugating enzyme Ubc12

1

4

High-throughput

0.479

High

653948

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.479

High

653951

WDR5
WD repeat-containing protein 5

1

13

High-throughput

0.479

High

653952

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

16

High-throughput

0.479

High

653953

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

653954

RS14
Small ribosomal subunit protein uS11

1

4

Small-scale

0.479

High

653955

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

653957

TBA1B
Tubulin alpha-1B chain

1

20

High-throughput

0.479

High

653962

SET
Protein SET

1

3

High-throughput

0.479

High

653964

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

653966

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

High-throughput

0.479

High

653967

TADBP
TAR DNA-binding protein 43

1

19

High-throughput

0.479

High

653968

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.479

High

653970

G3BP1
Ras GTPase-activating protein-binding protein 1

1

6

High-throughput

0.479

High

653972

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

653974

DCTN1
Dynactin subunit 1

1

19

High-throughput

0.479

High

653976

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

8

Small-scale

0.479

High

653980

TNIP1
TNFAIP3-interacting protein 1

1

13

High-throughput

0.479

High

653981

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

653982

PCBP1
Poly(rC)-binding protein 1

1

13

Small-scale

0.479

High

653988

CRY2
Cryptochrome-2

1

1

High-throughput

0.479

High

653990

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.479

High

653991

CE170
Centrosomal protein of 170 kDa

1

20

High-throughput

0.479

High

653993

A16L1
Autophagy-related protein 16-1

1

16

High-throughput

0.479

High

653994

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

653995

ANO7
Anoctamin-7

1

1

Small-scale

0.479

High

653996

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.479

High

653999

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

5

High-throughput

0.479

High

654005

PABP2
Polyadenylate-binding protein 2

1

12

High-throughput

0.479

High

654007

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

654008

ZCH18
Zinc finger CCCH domain-containing protein 18

1

19

High-throughput

0.479

High

654010

SMC5
Structural maintenance of chromosomes protein 5

1

9

High-throughput

0.479

High

654016

NUP43
Nucleoporin Nup43

1

19

High-throughput

0.479

High

654017

TIP
T-cell immunomodulatory protein

1

2

High-throughput

0.479

High

654023

HDAC2
Histone deacetylase 2

1

11

High-throughput

0.479

High

654027

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

High-throughput

0.479

High

654028

AP2M1
AP-2 complex subunit mu

1

10

High-throughput

0.479

High

654033

SNX27
Sorting nexin-27

1

20

High-throughput

0.479

High

654044

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

20

High-throughput

0.479

High

654045

ANM1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.479

High

654046

H2B1L
Histone H2B type 1-L

1

20

High-throughput

0.479

High

654049

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

3

High-throughput

0.479

High

654055

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

654057

NGB
Neuroglobin

1

1

High-throughput

0.479

High

654058

BRD7
Bromodomain-containing protein 7

1

16

High-throughput

0.479

High

654059

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.479

High

654061

ANLN
Anillin

1

3

High-throughput

0.479

High

654067

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

654068

HDAC6
Histone deacetylase 6

1

12

High-throughput

0.479

High

654069

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

654070

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

9

Small-scale

0.479

High

654072

BAG5
BAG family molecular chaperone regulator 5

1

3

High-throughput

0.479

High

654074

FZR1
Fizzy-related protein homolog

1

15

High-throughput

0.479

High

654077

MARE3
Microtubule-associated protein RP/EB family member 3

1

16

High-throughput

0.479

High

654009

H2A2B
Histone H2A type 2-B

1

14

High-throughput

0.470

High

547448

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

615650

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

653944

BID
BH3-interacting domain death agonist

1

0

Small-scale

0.458

High

654052

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

330865

PAK4
Serine/threonine-protein kinase PAK 4

1

9

High-throughput

0.445

High

377944

PRIO
Major prion protein

1

3

High-throughput

0.445

High

401463

JUN
Transcription factor Jun

1

8

High-throughput

0.445

High

581457

VCAM1
Vascular cell adhesion protein 1

1

15

High-throughput

0.445

High

653923

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.445

High

653956

YBOX1
Y-box-binding protein 1

1

4

Small-scale

0.445

High

654006

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

20

High-throughput

0.445

High

654019

RBCC1
RB1-inducible coiled-coil protein 1

1

18

High-throughput

0.445

High

654024

B2CL2
Bcl-2-like protein 2

1

1

High-throughput

0.445

High

654050

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.445

High

654053

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

12

High-throughput

0.445

High

653933

RXRG
Retinoic acid receptor RXR-gamma

1

20

High-throughput

0.439

High

100507

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

302938

HEXI1
Protein HEXIM1

1

1

High-throughput

0.437

High

520102

BMP4
Bone morphogenetic protein 4

1

1

High-throughput

0.437

High

569232

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.437

High

575281

EGR1
Early growth response protein 1

1

3

High-throughput

0.437

High

653934

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

653937

CDK9
Cyclin-dependent kinase 9

1

17

High-throughput

0.437

High

653969

RFA4
Replication protein A 30 kDa subunit

1

5

High-throughput

0.437

High

653979

EMC2
ER membrane protein complex subunit 2

1

11

High-throughput

0.437

High

653983

EZH2
Histone-lysine N-methyltransferase EZH2

1

11

High-throughput

0.437

High

653984

E2F4
Transcription factor E2F4

1

6

High-throughput

0.437

High

653992

DCA15
DDB1- and CUL4-associated factor 15

1

2

High-throughput

0.437

High

653998

LRC31
Leucine-rich repeat-containing protein 31

1

1

High-throughput

0.437

High

654000

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

654001

MOB3C
MOB kinase activator 3C

1

5

High-throughput

0.437

High

654003

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.437

High

654025

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.437

High

654040

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

654051

RNF38
E3 ubiquitin-protein ligase RNF38

1

1

Small-scale

0.437

High

654062

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.437

High

654065

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.437

High

654066

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

654073

HECD1
E3 ubiquitin-protein ligase HECTD1

1

19

High-throughput

0.437

High

654076

TRI33
E3 ubiquitin-protein ligase TRIM33

1

20

High-throughput

0.437

High

654082

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.437

High

654083

HYOU1
Hypoxia up-regulated protein 1

1

20

High-throughput

0.437

High

101656

F8VRK0
Tubulin alpha 1b

1

18

High-throughput

0.407

High

654031

C170L
Cep170-like protein

1

4

High-throughput

0.407

High

653935

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.373

High

653930

RAD52
DNA repair protein RAD52 homolog

1

0

High-throughput

0.279

Low

654002

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.279

Low

654036

PEO1
Twinkle mtDNA helicase

1

0

High-throughput

0.279

Low

182566

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

654020

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.249

Low

654079

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

654012

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024