Protein: TMOD1
Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)

Gene: TMOD1
Organism: Homo sapiens
Interactions: 147
UniProt ID: P28289

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005523 - tropomyosin binding
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005865 - striated muscle thin filament

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

657487

FLII
Protein flightless-1 homolog

4

12

High-throughput

0.895

High

413834

GELS
Gelsolin

3

11

High-throughput

0.861

High

657569

SCIN
Scinderin

3

11

High-throughput

0.861

High

657477

ACTB
Actin, cytoplasmic 1

2

12

High-throughput

0.789

High

657551

MYO5C
Unconventional myosin-Vc

4

6

High-throughput

0.699

High

657503

LRRF1
Leucine-rich repeat flightless-interacting protein 1

4

6

High-throughput

0.694

High

657481

ACTG
Actin, cytoplasmic 2

1

11

High-throughput

0.691

High

232643

TBCD4
TBC1 domain family member 4

3

1

High-throughput

0.667

High

657489

SNX1
Sorting nexin-1

3

2

High-throughput

0.667

High

657561

MYO5B
Unconventional myosin-Vb

3

8

High-throughput

0.667

High

657568

LRRF2
Leucine-rich repeat flightless-interacting protein 2

4

11

High-throughput

0.633

High

117599

MYO1C
Unconventional myosin-Ic

2

12

High-throughput

0.628

High

657501

DREB
Drebrin

2

2

High-throughput

0.628

High

313758

SVIL
Supervillin

1

11

High-throughput

0.618

High

657479

ACTA
Actin, aortic smooth muscle

1

11

High-throughput

0.618

High

657550

ANLN
Anillin

2

3

High-throughput

0.611

High

657523

NIN
Ninein

3

8

High-throughput

0.609

High

657565

CBPC1
Cytosolic carboxypeptidase 1

2

0

High-throughput

0.585

High

167069

ARHGB
Rho guanine nucleotide exchange factor 11

2

10

High-throughput

0.571

High

210987

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

3

High-throughput

0.541

High

521741

CADH1
Cadherin-1

1

2

High-throughput

0.541

High

657466

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.541

High

657468

DCC
Netrin receptor DCC

1

1

High-throughput

0.541

High

657532

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.541

High

657540

RHG07
Rho GTPase-activating protein 7

1

3

High-throughput

0.541

High

214510

MYO1B
Unconventional myosin-Ib

1

12

High-throughput

0.536

High

597969

FLNA
Filamin-A

1

2

High-throughput

0.536

High

625136

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.536

High

657461

LSP1
Lymphocyte-specific protein 1

1

1

High-throughput

0.536

High

657463

MYH9
Myosin-9

1

1

High-throughput

0.536

High

657469

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

6

High-throughput

0.536

High

657470

CAZA2
F-actin-capping protein subunit alpha-2

1

8

High-throughput

0.536

High

657471

CAPZB
F-actin-capping protein subunit beta

1

6

High-throughput

0.536

High

657478

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

2

High-throughput

0.536

High

657485

CALD1
Caldesmon

1

15

High-throughput

0.536

High

657504

PKHG6
Pleckstrin homology domain-containing family G member 6

1

12

High-throughput

0.536

High

657517

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.536

High

657521

ABRA
Actin-binding Rho-activating protein

1

2

High-throughput

0.536

High

657522

SYNPO
Synaptopodin

1

1

High-throughput

0.536

High

657530

MY18A
Unconventional myosin-XVIIIa

1

10

High-throughput

0.536

High

657537

MYO19
Unconventional myosin-XIX

1

9

High-throughput

0.536

High

657542

GA2L1
GAS2-like protein 1

1

1

High-throughput

0.536

High

657552

PDLI7
PDZ and LIM domain protein 7

1

3

High-throughput

0.536

High

657558

LIMA1
LIM domain and actin-binding protein 1

1

2

High-throughput

0.536

High

516203

DCOR
Ornithine decarboxylase

1

0

High-throughput

0.518

High

626053

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.518

High

526644

GILT
Gamma-interferon-inducible lysosomal thiol reductase

1

0

High-throughput

0.513

High

574248

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

606955

SCP2
Sterol carrier protein 2

1

0

High-throughput

0.513

High

657464

ADDA
Alpha-adducin

1

0

High-throughput

0.513

High

657465

PSB10
Proteasome subunit beta type-10

1

0

High-throughput

0.513

High

657473

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

1

0

High-throughput

0.513

High

657492

PDE7A
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A

1

0

High-throughput

0.513

High

657493

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

657499

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

657500

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.513

High

657502

SAMTR
S-adenosylmethionine sensor upstream of mTORC1

1

0

High-throughput

0.513

High

657509

RRAGB
Ras-related GTP-binding protein B

1

0

High-throughput

0.513

High

657535

ZMY19
Zinc finger MYND domain-containing protein 19

1

0

High-throughput

0.513

High

657536

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

657554

PNO1
RNA-binding protein PNO1

1

0

High-throughput

0.513

High

596193

NEBU
Nebulin

1

3

Small-scale

0.501

High

237472

TLR2
Toll-like receptor 2

1

1

High-throughput

0.494

High

657472

DAPK1
Death-associated protein kinase 1

1

4

High-throughput

0.489

High

657495

HLX
H2.0-like homeobox protein

1

5

High-throughput

0.489

High

657524

S2541
Mitochondrial carrier protein SCaMC-3L

1

3

High-throughput

0.489

High

657539

BIRC8
Baculoviral IAP repeat-containing protein 8

1

6

High-throughput

0.489

High

657546

LPAR2
Lysophosphatidic acid receptor 2

1

2

High-throughput

0.489

High

657549

C1QR1
Complement component C1q receptor

1

3

High-throughput

0.489

High

657556

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

1

High-throughput

0.489

High

657467

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

5

High-throughput

0.481

High

657475

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

2

Small-scale

0.481

High

130759

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

4

High-throughput

0.479

High

150525

ABLM1
Actin-binding LIM protein 1

1

1

High-throughput

0.479

High

215196

STRN
Striatin

1

2

High-throughput

0.479

High

264008

TACC1
Transforming acidic coiled-coil-containing protein 1

1

1

High-throughput

0.479

High

272493

OFD1
Centriole and centriolar satellite protein OFD1

1

10

High-throughput

0.479

High

294409

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

302481

CE152
Centrosomal protein of 152 kDa

1

2

High-throughput

0.479

High

317212

PCNT
Pericentrin

1

7

High-throughput

0.479

High

373728

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

418886

TPM3
Tropomyosin alpha-3 chain

1

6

High-throughput

0.479

High

451196

TPM1
Tropomyosin alpha-1 chain

1

6

High-throughput

0.479

High

505560

EPB41
Protein 4.1

1

1

High-throughput

0.479

High

548647

VAV
Proto-oncogene vav

1

11

High-throughput

0.479

High

657474

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

657482

TPM4
Tropomyosin alpha-4 chain

1

6

High-throughput

0.479

High

657488

GOGA4
Golgin subfamily A member 4

1

7

High-throughput

0.479

High

657490

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

3

High-throughput

0.479

High

657494

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

1

High-throughput

0.479

High

657496

GOGB1
Golgin subfamily B member 1

1

6

High-throughput

0.479

High

657497

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

3

High-throughput

0.479

High

657498

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

657505

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

2

High-throughput

0.479

High

657506

RHG21
Rho GTPase-activating protein 21

1

2

High-throughput

0.479

High

657508

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.479

High

657514

MPRIP
Myosin phosphatase Rho-interacting protein

1

7

High-throughput

0.479

High

657516

CRACD
Capping protein-inhibiting regulator of actin dynamics

1

7

High-throughput

0.479

High

657520

GCC2
GRIP and coiled-coil domain-containing protein 2

1

5

High-throughput

0.479

High

657525

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

4

High-throughput

0.479

High

657528

LMO7
LIM domain only protein 7

1

2

High-throughput

0.479

High

657529

TSC1
Hamartin

1

6

High-throughput

0.479

High

657541

NEB2
Neurabin-2

1

4

High-throughput

0.479

High

657548

CENPJ
Centromere protein J

1

4

High-throughput

0.479

High

657553

STRN4
Striatin-4

1

3

High-throughput

0.479

High

657562

CLC4E
C-type lectin domain family 4 member E

1

5

High-throughput

0.479

High

657563

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

3

High-throughput

0.479

High

657564

CP131
Centrosomal protein of 131 kDa

1

3

High-throughput

0.479

High

657566

WIPI4
WD repeat domain phosphoinositide-interacting protein 4

1

2

High-throughput

0.479

High

657557

FXL17
F-box/LRR-repeat protein 17

1

0

Small-scale

0.460

High

200504

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.458

High

202595

TXNL1
Thioredoxin-like protein 1

1

0

High-throughput

0.458

High

657480

H4
Histone H4

1

0

High-throughput

0.458

High

657543

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.458

High

657462

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.445

High

657476

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

High-throughput

0.445

High

657511

PKHA7
Pleckstrin homology domain-containing family A member 7

1

5

High-throughput

0.445

High

657531

CSN5
COP9 signalosome complex subunit 5

1

4

Small-scale

0.445

High

657533

Q96D37
VAV1 protein

1

11

High-throughput

0.445

High

657526

ARF
Tumor suppressor ARF

1

0

High-throughput

0.438

High

100511

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

216904

KIF1C
Kinesin-like protein KIF1C

1

3

High-throughput

0.437

High

345998

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.437

High

384319

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

657484

VIGLN
Vigilin

1

2

High-throughput

0.437

High

657486

NEXN
Nexilin

1

1

High-throughput

0.437

High

657507

CCD18
Coiled-coil domain-containing protein 18

1

7

High-throughput

0.437

High

657510

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

5

High-throughput

0.437

High

657518

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

7

High-throughput

0.437

High

657519

LRC49
Leucine-rich repeat-containing protein 49

1

1

High-throughput

0.437

High

657527

DLG5
Disks large homolog 5

1

1

High-throughput

0.437

High

657567

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

239796

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

657559

MLH3
DNA mismatch repair protein Mlh3

1

0

High-throughput

0.282

High

403598

AP2A
Transcription factor AP-2-alpha

1

0

High-throughput

0.279

Low

657483

RT05
Small ribosomal subunit protein uS5m

1

0

High-throughput

0.279

Low

657512

KLH10
Kelch-like protein 10

1

0

High-throughput

0.279

Low

657513

RSLBA
Ras-like protein family member 11A

1

0

High-throughput

0.279

Low

657534

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.279

Low

657544

ASHWN
Ashwin

1

0

High-throughput

0.279

Low

657547

PROK2
Prokineticin-2

1

0

High-throughput

0.279

Low

657555

GKN1
Gastrokine-1

1

0

High-throughput

0.279

Low

657491

TBB2A
Tubulin beta-2A chain

1

0

High-throughput

0.249

Low

657515

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.249

Low

657538

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

657545

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

657560

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024