Protein: GDE
Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)]

Gene: GDE, AGL
Organism: Homo sapiens
Interactions: 69
UniProt ID: P35573

Gene Ontology (top 5):
GO:0004133 - glycogen debranching enzyme activity
GO:0004134 - 4-alpha-glucanotransferase activity
GO:0004135 - amylo-alpha-1,6-glucosidase activity
GO:0005576 - extracellular region
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

307595

STBD1
Starch-binding domain-containing protein 1

2

0

High-throughput

0.602

High

180630

GLYG2
Glycogenin-2

1

1

High-throughput

0.536

High

647840

MARK3
MAP/microtubule affinity-regulating kinase 3

1

1

High-throughput

0.536

High

724640

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

High-throughput

0.536

High

724648

CUL1
Cullin-1

1

4

High-throughput

0.536

High

724649

CUL2
Cullin-2

1

4

High-throughput

0.536

High

724650

CUL3
Cullin-3

1

4

High-throughput

0.536

High

724651

CUL4B
Cullin-4B

1

4

High-throughput

0.536

High

724667

CUL5
Cullin-5

1

4

High-throughput

0.536

High

724678

DP13A
DCC-interacting protein 13-alpha

1

0

High-throughput

0.518

High

212368

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

0

High-throughput

0.513

High

506162

PYGB
Glycogen phosphorylase, brain form

1

0

High-throughput

0.513

High

549871

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

0

High-throughput

0.513

High

724639

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

0

High-throughput

0.513

High

724646

CDK5
Cyclin-dependent kinase 5

1

0

High-throughput

0.513

High

724663

RASF5
Ras association domain-containing protein 5

1

0

High-throughput

0.513

High

724666

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

724669

AURKB
Aurora kinase B

1

0

High-throughput

0.513

High

724670

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

724680

FOXA2
Hepatocyte nuclear factor 3-beta

1

0

High-throughput

0.513

High

226678

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

312499

ARI2
E3 ubiquitin-protein ligase ARIH2

1

1

High-throughput

0.479

High

724647

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

724655

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

724664

ASB15
Ankyrin repeat and SOCS box protein 15

1

1

High-throughput

0.479

High

724679

TRI33
E3 ubiquitin-protein ligase TRIM33

1

1

High-throughput

0.479

High

724682

ASB3
Ankyrin repeat and SOCS box protein 3

1

1

High-throughput

0.479

High

302968

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

314250

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.458

High

373789

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

496437

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.458

High

503554

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

552078

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

575298

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

575699

VINC
Vinculin

1

0

High-throughput

0.458

High

650508

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

724637

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

724638

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

724642

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

724645

VIGLN
Vigilin

1

0

High-throughput

0.458

High

724653

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.458

High

724654

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

724656

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

724657

TENS2
Tensin-2

1

0

High-throughput

0.458

High

724658

NHLC1
E3 ubiquitin-protein ligase NHLRC1

1

0

Small-scale

0.458

High

724659

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

724660

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

724665

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

724668

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

724671

RN126
E3 ubiquitin-protein ligase RNF126

1

0

High-throughput

0.458

High

724676

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

724641

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

1

High-throughput

0.445

High

724675

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.445

High

377966

PRIO
Major prion protein

1

0

High-throughput

0.426

High

414193

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.426

High

724643

CBX1
Chromobox protein homolog 1

1

0

Small-scale

0.426

High

724644

SMAD3
Mothers against decapentaplegic homolog 3

1

0

Small-scale

0.426

High

724677

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.426

High

724681

SHLB1
Endophilin-B1

1

0

High-throughput

0.426

High

312782

M3K6
Mitogen-activated protein kinase kinase kinase 6

1

0

High-throughput

0.279

Low

724652

FASTK
Fas-activated serine/threonine kinase

1

0

High-throughput

0.279

Low

100547

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

384383

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

719817

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

724661

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

724662

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

724672

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low

724674

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

Small-scale

0.249

Low

724673

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024