Protein: FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha)

Gene: FNTA
Organism: Homo sapiens
Interactions: 70
UniProt ID: P49354

Gene Ontology (top 5):
GO:0004660 - protein farnesyltransferase activity
GO:0004661 - protein geranylgeranyltransferase activity
GO:0004662 - CAAX-protein geranylgeranyltransferase activity
GO:0004663 - Rab geranylgeranyltransferase activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

826390

FNTB
Protein farnesyltransferase subunit beta

11

18

Small-scale

0.979

High

826394

PGTB1
Geranylgeranyl transferase type-1 subunit beta

4

18

High-throughput

0.902

High

826408

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

5

0

High-throughput

0.686

High

826406

TP4A2
Protein tyrosine phosphatase type IVA 2

3

2

High-throughput

0.662

High

826395

NP1L1
Nucleosome assembly protein 1-like 1

3

0

High-throughput

0.638

High

826432

HEYL
Hairy/enhancer-of-split related with YRPW motif-like protein

3

0

High-throughput

0.638

High

427861

CAN1
Calpain-1 catalytic subunit

2

1

High-throughput

0.628

High

826404

RL18
Large ribosomal subunit protein eL18

2

0

High-throughput

0.602

High

826421

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

2

0

High-throughput

0.602

High

826430

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

2

0

High-throughput

0.602

High

826431

E41L5
Band 4.1-like protein 5

2

0

High-throughput

0.602

High

826435

TSKS
Testis-specific serine kinase substrate

2

0

High-throughput

0.602

High

119707

AP4M1
AP-4 complex subunit mu-1

2

0

High-throughput

0.580

High

826397

CDC42
Cell division control protein 42 homolog

2

1

High-throughput

0.571

High

738510

TGFR1
TGF-beta receptor type-1

1

1

Small-scale

0.549

High

826389

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

0

High-throughput

0.546

High

826434

HDAC6
Histone deacetylase 6

1

0

Small-scale

0.537

High

180832

YKT6
Synaptobrevin homolog YKT6

1

2

High-throughput

0.536

High

568954

CAN2
Calpain-2 catalytic subunit

1

1

High-throughput

0.536

High

826423

RAB2B
Ras-related protein Rab-2B

1

7

High-throughput

0.536

High

826426

TP4A1
Protein tyrosine phosphatase type IVA 1

1

2

High-throughput

0.536

High

528767

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

826392

STAT2
Signal transducer and activator of transcription 2

1

0

High-throughput

0.518

High

826409

SAFB2
Scaffold attachment factor B2

1

0

High-throughput

0.518

High

673669

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

0

High-throughput

0.513

High

826391

CENPF
Centromere protein F

1

0

High-throughput

0.513

High

826398

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.513

High

826400

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

826403

FAK1
Focal adhesion kinase 1

1

0

High-throughput

0.513

High

826407

DGKZ
Diacylglycerol kinase zeta

1

0

High-throughput

0.513

High

826410

K1H1
Keratin, type I cuticular Ha1

1

0

High-throughput

0.513

High

826417

CENPV
Centromere protein V

1

0

High-throughput

0.513

High

826418

RIOX2
Ribosomal oxygenase 2

1

0

High-throughput

0.513

High

826419

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.513

High

826420

OGFD1
Prolyl 3-hydroxylase OGFOD1

1

0

High-throughput

0.513

High

826422

RN169
E3 ubiquitin-protein ligase RNF169

1

0

High-throughput

0.513

High

826424

SNX33
Sorting nexin-33

1

0

High-throughput

0.513

High

826427

SPDLY
Protein Spindly

1

0

High-throughput

0.513

High

826428

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.513

High

826433

LATS2
Serine/threonine-protein kinase LATS2

1

0

High-throughput

0.513

High

826437

T53G5
TP53-target gene 5 protein

1

0

High-throughput

0.513

High

174710

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

451819

INHBB
Inhibin beta B chain

1

1

High-throughput

0.494

High

826393

VAV2
Guanine nucleotide exchange factor VAV2

1

0

High-throughput

0.486

High

351305

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

1

Small-scale

0.481

High

826402

ACVR1
Activin receptor type-1

1

1

Small-scale

0.481

High

226837

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

260531

TP4A3
Protein tyrosine phosphatase type IVA 3

1

2

High-throughput

0.479

High

826415

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

602816

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.460

High

773273

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.460

High

826405

GRSF1
G-rich sequence factor 1

1

0

Small-scale

0.460

High

294523

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

610297

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

826425

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

826436

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.458

High

377984

PRIO
Major prion protein

1

0

High-throughput

0.426

High

826399

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.426

High

826413

AMERL
AMMECR1-like protein

3

0

High-throughput

0.347

High

826414

F117B
Protein FAM117B

2

0

High-throughput

0.328

High

826416

CEFIP
Cardiac-enriched FHL2-interacting protein

2

0

High-throughput

0.328

High

817010

TFPI2
Tissue factor pathway inhibitor 2

1

0

High-throughput

0.279

Low

826396

RRP1
Ribosomal RNA processing protein 1 homolog A

1

0

High-throughput

0.279

Low

826401

LMNB2
Lamin-B2

1

0

High-throughput

0.279

Low

826411

ZMYM1
Zinc finger MYM-type protein 1

1

0

High-throughput

0.279

Low

826412

ZN691
Zinc finger protein 691

1

0

High-throughput

0.279

Low

826429

GDAH
Guanidino acid hydrolase, mitochondrial

1

0

High-throughput

0.279

Low

100587

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

826438

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024