Protein: HINT1
Adenosine 5'-monophosphoramidase HINT1 (EC 3.9.1.-) (Desumoylating isopeptidase HINT1) (EC 3.4.22.-) (Histidine triad nucleotide-binding protein 1) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1)

Gene: HINT1
Organism: Homo sapiens
Interactions: 92
UniProt ID: P49773

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000166 - nucleotide binding
GO:0005080 - protein kinase C binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834470

HINT1
Adenosine 5'-monophosphoramidase HINT1

3

15

Small-scale

0.827

High

834498

HDAC7
Histone deacetylase 7

3

1

High-throughput

0.667

High

834472

CDK9
Cyclin-dependent kinase 9

3

0

High-throughput

0.638

High

716878

CTNB1
Catenin beta-1

2

2

Small-scale

0.620

High

331469

ACL6A
Actin-like protein 6A

2

1

High-throughput

0.611

High

834504

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

2

0

High-throughput

0.602

High

719971

RFA3
Replication protein A 14 kDa subunit

2

0

High-throughput

0.585

High

226863

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

834494

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

2

0

High-throughput

0.580

High

834516

RUVB2
RuvB-like 2

1

1

Small-scale

0.578

High

834517

RUVB1
RuvB-like 1

1

1

Small-scale

0.578

High

283177

RGS20
Regulator of G-protein signaling 20

1

2

Small-scale

0.552

High

834510

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

1

Small-scale

0.552

High

601852

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

0

High-throughput

0.551

High

827866

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

Small-scale

0.537

High

834476

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.537

High

336418

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

496569

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.536

High

834509

HINT3
Adenosine 5'-monophosphoramidase HINT3

1

15

High-throughput

0.536

High

834521

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.536

High

252910

MITF
Microphthalmia-associated transcription factor

1

0

Small-scale

0.529

High

201268

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

235268

OGA
Protein O-GlcNAcase

1

0

High-throughput

0.513

High

734889

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

0

High-throughput

0.513

High

834473

ZN131
Zinc finger protein 131

1

0

High-throughput

0.513

High

834481

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

834488

KDM4D
Lysine-specific demethylase 4D

1

0

High-throughput

0.513

High

834490

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.513

High

834497

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.513

High

834499

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

834508

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.513

High

834520

AMMR1
Nuclear protein AMMECR1

1

0

High-throughput

0.513

High

738603

GNL1
Guanine nucleotide-binding protein-like 1

1

0

High-throughput

0.493

High

834474

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.493

High

834471

RGS19
Regulator of G-protein signaling 19

1

2

Small-scale

0.481

High

834511

RGS17
Regulator of G-protein signaling 17

1

2

Small-scale

0.481

High

435011

SP1
Transcription factor Sp1

1

0

Small-scale

0.480

High

346239

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

351991

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.479

High

354366

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.479

High

379131

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

381861

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

455219

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

834478

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

834491

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

834500

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

834503

SCLT1
Sodium channel and clathrin linker 1

1

1

High-throughput

0.479

High

834512

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

834513

LEF1
Lymphoid enhancer-binding factor 1

1

1

Small-scale

0.479

High

834514

HDAC9
Histone deacetylase 9

1

1

Small-scale

0.479

High

834482

CDC16
Cell division cycle protein 16 homolog

1

0

High-throughput

0.460

High

834515

TEN1
Teneurin-1

1

0

Small-scale

0.460

High

244119

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

272517

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

552233

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

569392

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

641668

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.458

High

650674

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

669929

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

Small-scale

0.458

High

675138

CLIP1
CAP-Gly domain-containing linker protein 1

1

0

High-throughput

0.458

High

714794

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.458

High

742132

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

771835

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

779022

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

781869

PERI
Peripherin

1

0

High-throughput

0.458

High

834475

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

834477

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

834480

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

834484

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

834485

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

834489

DEN5A
DENN domain-containing protein 5A

1

0

High-throughput

0.458

High

834492

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

834495

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

834496

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

834501

KAT5
Histone acetyltransferase KAT5

1

0

Small-scale

0.458

High

834505

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.458

High

834506

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

834507

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

834518

FBW1A
F-box/WD repeat-containing protein 1A

1

0

Small-scale

0.458

High

377988

PRIO
Major prion protein

1

1

High-throughput

0.445

High

382349

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

1

High-throughput

0.445

High

528779

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

834486

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

100596

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

834479

RT25
Small ribosomal subunit protein mS25

1

1

High-throughput

0.437

High

834493

SFPA2
Pulmonary surfactant-associated protein A2

1

0

High-throughput

0.279

Low

834519

SNX24
Sorting nexin-24

1

0

High-throughput

0.279

Low

390776

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

834487

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

834502

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

834483

TRI29
Tripartite motif-containing protein 29

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024