Protein: KLK7
Kallikrein-7 (hK7) (EC 3.4.21.117) (Serine protease 6) (Stratum corneum chymotryptic enzyme) (hSCCE)

Gene: KLK7
Organism: Homo sapiens
Interactions: 77
UniProt ID: P49862

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0002803 - positive regulation of antibacterial peptide production
GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548662

VAV
Proto-oncogene vav

2

1

High-throughput

0.726

High

394348

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.647

High

365170

FRIH
Ferritin heavy chain

2

3

High-throughput

0.628

High

836310

LRC10
Leucine-rich repeat-containing protein 10

1

1

High-throughput

0.618

High

836334

ISK5
Serine protease inhibitor Kazal-type 5

1

9

Small-scale

0.618

High

836304

KI3S1
Killer cell immunoglobulin-like receptor 3DS1

3

1

High-throughput

0.609

High

836328

GMCL1
Germ cell-less protein-like 1

3

3

High-throughput

0.609

High

315882

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.602

High

836318

UBAC2
Ubiquitin-associated domain-containing protein 2

2

0

High-throughput

0.585

High

836329

CDK15
Cyclin-dependent kinase 15

2

1

High-throughput

0.574

High

836337

TB22B
TBC1 domain family member 22B

2

1

High-throughput

0.574

High

836346

FCF1
rRNA-processing protein FCF1 homolog

2

1

High-throughput

0.574

High

351309

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

8

High-throughput

0.541

High

599634

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

1

High-throughput

0.536

High

676731

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

2

High-throughput

0.536

High

836299

UBE3A
Ubiquitin-protein ligase E3A

1

3

High-throughput

0.536

High

836335

TSSP
Thymus-specific serine protease

1

2

High-throughput

0.536

High

836343

PCOC2
Procollagen C-endopeptidase enhancer 2

1

12

High-throughput

0.536

High

328116

SG1D1
Secretoglobin family 1D member 1

1

0

High-throughput

0.513

High

392926

IFNA4
Interferon alpha-4

1

0

High-throughput

0.513

High

836330

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.513

High

429306

SAP
Prosaposin

1

1

Small-scale

0.501

High

836297

CAMP
Cathelicidin antimicrobial peptide

1

2

Small-scale

0.501

High

314021

BAG4
BAG family molecular chaperone regulator 4

1

3

High-throughput

0.494

High

331233

CHK2
Serine/threonine-protein kinase Chk2

1

1

High-throughput

0.494

High

573615

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

9

High-throughput

0.494

High

585894

WT1
Wilms tumor protein

1

2

High-throughput

0.494

High

622402

CCND1
G1/S-specific cyclin-D1

1

2

High-throughput

0.494

High

836301

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

10

High-throughput

0.494

High

836306

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.494

High

206900

CHSTA
Carbohydrate sulfotransferase 10

1

3

High-throughput

0.489

High

265618

E2F6
Transcription factor E2F6

1

1

High-throughput

0.489

High

274962

RENR
Renin receptor

1

2

High-throughput

0.489

High

297474

TOX4
TOX high mobility group box family member 4

1

4

High-throughput

0.489

High

518291

ADT3
ADP/ATP translocase 3

1

11

High-throughput

0.489

High

624413

CCNC
Cyclin-C

1

1

High-throughput

0.489

High

686616

CCR1
C-C chemokine receptor type 1

1

6

High-throughput

0.489

High

821530

PTSS1
Phosphatidylserine synthase 1

1

1

High-throughput

0.489

High

836298

STX17
Syntaxin-17

1

4

High-throughput

0.489

High

836300

GABPA
GA-binding protein alpha chain

1

2

High-throughput

0.489

High

836308

CR021
UPF0711 protein C18orf21

1

2

High-throughput

0.489

High

836316

UB2J2
Ubiquitin-conjugating enzyme E2 J2

1

2

High-throughput

0.489

High

836319

EHBP1
EH domain-binding protein 1

1

2

High-throughput

0.489

High

836321

TRI41
E3 ubiquitin-protein ligase TRIM41

1

1

High-throughput

0.489

High

836322

ZDH19
Palmitoyltransferase ZDHHC19

1

2

High-throughput

0.489

High

836323

SIA8A
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

1

4

High-throughput

0.489

High

836324

PIGT
GPI transamidase component PIG-T

1

3

High-throughput

0.489

High

836325

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

4

High-throughput

0.489

High

836331

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.489

High

836333

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

9

High-throughput

0.489

High

836336

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.489

High

836338

KLH11
Kelch-like protein 11

1

1

High-throughput

0.489

High

836340

DTL
Denticleless protein homolog

1

1

High-throughput

0.489

High

836342

PHF11
PHD finger protein 11

1

3

High-throughput

0.489

High

836344

PHF8
Histone lysine demethylase PHF8

1

1

High-throughput

0.489

High

836345

SSUH2
Protein SSUH2 homolog

1

4

High-throughput

0.489

High

836305

CDSN
Corneodesmosin

1

0

Small-scale

0.480

High

836309

Q4LE69
1-phosphatidylinositol 4-kinase

1

5

High-throughput

0.437

High

836332

FACD2
Fanconi anemia group D2 protein

1

5

High-throughput

0.437

High

836339

PLK2
Serine/threonine-protein kinase PLK2

1

1

High-throughput

0.437

High

787635

PI4KA
Phosphatidylinositol 4-kinase alpha

1

5

High-throughput

0.407

High

836317

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

5

High-throughput

0.407

High

716574

CAH8
Carbonic anhydrase-related protein

3

0

High-throughput

0.347

High

836314

PLCZ1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

3

0

High-throughput

0.347

High

674301

PURA2
Adenylosuccinate synthetase isozyme 2

1

0

High-throughput

0.279

Low

836302

ZN154
Zinc finger protein 154

1

0

High-throughput

0.279

Low

836303

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

0

High-throughput

0.279

Low

836307

ZIC1
Zinc finger protein ZIC 1

1

0

High-throughput

0.279

Low

836311

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.279

Low

836312

AROS
Active regulator of SIRT1

1

0

High-throughput

0.279

Low

836313

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

0

High-throughput

0.279

Low

836315

EPHX4
Epoxide hydrolase 4

1

0

High-throughput

0.279

Low

836320

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.279

Low

836326

TOM6
Mitochondrial import receptor subunit TOM6 homolog

1

0

High-throughput

0.279

Low

836327

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.279

Low

836341

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

1

0

High-throughput

0.279

Low

100597

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024