Protein: SSDH
Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase)

Gene: SSDH, ALDH5A1
Organism: Homo sapiens
Interactions: 43
UniProt ID: P51649

Gene Ontology (top 5):
GO:0004777 - succinate-semialdehyde dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol
GO:0006105 - succinate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849012

SSDH
Succinate-semialdehyde dehydrogenase, mitochondrial

1

13

Small-scale

0.647

High

849017

FGL1
Fibrinogen-like protein 1

3

3

High-throughput

0.609

High

849021

OXLD1
Oxidoreductase-like domain-containing protein 1

2

0

High-throughput

0.585

High

226911

PRKN
E3 ubiquitin-protein ligase parkin

2

10

High-throughput

0.584

High

296513

KPCD3
Serine/threonine-protein kinase D3

1

2

High-throughput

0.536

High

849015

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.536

High

849024

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

3

High-throughput

0.536

High

849025

AHI1
Jouberin

1

7

High-throughput

0.536

High

796258

MAGAB
Melanoma-associated antigen 11

1

0

High-throughput

0.518

High

212044

GATC
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

1

0

High-throughput

0.513

High

840887

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.513

High

849019

RM23
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.513

High

849026

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.513

High

849027

GLMP
Glycosylated lysosomal membrane protein

1

0

High-throughput

0.513

High

849030

IRAK4
Interleukin-1 receptor-associated kinase 4

1

0

High-throughput

0.513

High

849033

MSRB2
Methionine-R-sulfoxide reductase B2, mitochondrial

1

0

High-throughput

0.513

High

174734

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

377193

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

849013

TERA
Transitional endoplasmic reticulum ATPase

1

2

Small-scale

0.479

High

849016

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

849020

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

3

High-throughput

0.479

High

849028

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

849031

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

242024

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

381873

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

503716

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

377993

PRIO
Major prion protein

1

1

High-throughput

0.445

High

496600

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.445

High

587475

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

High-throughput

0.445

High

849022

CP135
Centrosomal protein of 135 kDa

1

3

High-throughput

0.445

High

100609

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

552277

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

720015

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

749250

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.437

High

849023

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

849018

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.426

High

517139

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.417

High

401670

JUN
Transcription factor Jun

1

3

High-throughput

0.407

High

849029

CLIC6
Chloride intracellular channel protein 6

1

0

High-throughput

0.282

High

849032

GPR55
G-protein coupled receptor 55

1

0

High-throughput

0.279

Low

650718

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

849014

KLF3
Krueppel-like factor 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024