Protein: IST1
IST1 homolog (hIST1) (Charged multivesicular body protein 8) (CHMP8) (Putative MAPK-activating protein PM28)

Gene: IST1
Organism: Homo sapiens
Interactions: 83
UniProt ID: P53990

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005576 - extracellular region
GO:0005635 - nuclear envelope
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

867068

CHM1A
Charged multivesicular body protein 1a

5

13

High-throughput

0.714

High

533371

ACPH
Acylamino-acid-releasing enzyme

5

0

High-throughput

0.692

High

867047

CHM1B
Charged multivesicular body protein 1b

4

13

Small-scale

0.690

High

867077

UBQL1
Ubiquilin-1

3

1

High-throughput

0.675

High

867039

ATX1
Ataxin-1

4

0

High-throughput

0.674

High

867072

SPAST
Spastin

3

8

Small-scale

0.674

High

867038

IST1
IST1 homolog

1

2

Small-scale

0.666

High

867078

VPS4A
Vacuolar protein sorting-associated protein 4A

2

8

High-throughput

0.628

High

867084

CAN7
Calpain-7

2

1

Small-scale

0.625

High

867074

UBQL2
Ubiquilin-2

2

1

High-throughput

0.606

High

867064

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

2

0

High-throughput

0.602

High

867079

VP9D1
VPS9 domain-containing protein 1

2

0

High-throughput

0.595

High

609775

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

2

0

High-throughput

0.585

High

867073

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

2

0

High-throughput

0.585

High

314024

BAG4
BAG family molecular chaperone regulator 4

2

0

High-throughput

0.580

High

369241

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

581570

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.571

High

159933

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.536

High

259716

PDCD6
Programmed cell death protein 6

1

3

High-throughput

0.536

High

277034

STAM2
Signal transducing adapter molecule 2

1

2

High-throughput

0.536

High

451401

CLCA
Clathrin light chain A

1

1

High-throughput

0.536

High

451655

CLCB
Clathrin light chain B

1

1

High-throughput

0.536

High

844836

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.536

High

867060

STAM1
Signal transducing adapter molecule 1

1

2

High-throughput

0.536

High

867066

CHM4B
Charged multivesicular body protein 4b

1

9

High-throughput

0.536

High

867069

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

1

1

High-throughput

0.536

High

867071

CHMP5
Charged multivesicular body protein 5

1

13

High-throughput

0.536

High

234493

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.518

High

274973

RENR
Renin receptor

1

0

High-throughput

0.513

High

580346

TSN8
Tetraspanin-8

1

0

High-throughput

0.513

High

867042

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

867059

TFG
Protein TFG

1

0

High-throughput

0.513

High

867062

MB12A
Multivesicular body subunit 12A

1

0

High-throughput

0.513

High

867080

NTNG1
Netrin-G1

1

0

High-throughput

0.513

High

867081

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

777020

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.493

High

867082

MB212
Protein mab-21-like 2

1

1

High-throughput

0.489

High

125273

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

Small-scale

0.480

High

174744

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

226956

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

362965

FINC
Fibronectin

1

1

High-throughput

0.479

High

397863

ISG15
Ubiquitin-like protein ISG15

1

1

Small-scale

0.479

High

547324

VATB1
V-type proton ATPase subunit B, kidney isoform

1

1

High-throughput

0.479

High

867043

CDC20
Cell division cycle protein 20 homolog

1

1

Small-scale

0.479

High

867054

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

867056

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

867058

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

867063

BICD1
Protein bicaudal D homolog 1

1

1

High-throughput

0.479

High

867076

FZR1
Fizzy-related protein homolog

1

1

Small-scale

0.479

High

867048

Q7Z479
Calpain 7

1

1

High-throughput

0.470

High

178914

TOX3
TOX high mobility group box family member 3

1

0

High-throughput

0.460

High

513974

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.458

High

521825

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

530527

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

590740

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

719424

MERL
Merlin

1

0

High-throughput

0.458

High

742157

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

779081

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

844454

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.458

High

867040

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

867041

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

867049

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

867050

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

867052

RHG18
Rho GTPase-activating protein 18

1

0

High-throughput

0.458

High

867075

ANC2
Anaphase-promoting complex subunit 2

1

0

Small-scale

0.458

High

867070

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

750824

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.426

High

452691

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

867045

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.279

Low

867051

LSME2
Leucine-rich single-pass membrane protein 2

1

0

High-throughput

0.279

Low

867055

S2540
Mitochondrial glutathione transporter SLC25A40

1

0

High-throughput

0.279

Low

867057

CD003
Uncharacterized protein C4orf3

1

0

High-throughput

0.279

Low

867061

ISOC1
Isochorismatase domain-containing protein 1

1

0

High-throughput

0.279

Low

867065

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.279

Low

867083

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.279

Low

100620

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

233306

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

867046

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

867053

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

867067

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

239873

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

867044

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024