Protein: PAR2
Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]

Gene: PAR2, F2RL1
Organism: Homo sapiens
Interactions: 177
UniProt ID: P55085

Gene Ontology (top 5):
GO:0001965 - G-protein alpha-subunit binding
GO:0002020 - protease binding
GO:0002286 - T cell activation involved in immune response
GO:0002690 - positive regulation of leukocyte chemotaxis
GO:0002720 - positive regulation of cytokine production involved in immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

814001

RGR
RPE-retinal G protein-coupled receptor

1

16

High-throughput

0.698

High

876108

SCN1B
Sodium channel subunit beta-1

1

1

High-throughput

0.698

High

171968

GP182
G-protein coupled receptor 182

1

17

High-throughput

0.691

High

876103

CXCR4
C-X-C chemokine receptor type 4

1

18

High-throughput

0.691

High

876119

SLMAP
Sarcolemmal membrane-associated protein

3

3

High-throughput

0.667

High

876213

TMX2
Thioredoxin-related transmembrane protein 2

1

1

High-throughput

0.625

High

876125

TMED2
Transmembrane emp24 domain-containing protein 2

2

7

Small-scale

0.608

High

876171

CSN5
COP9 signalosome complex subunit 5

1

5

Small-scale

0.594

High

561538

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

20

High-throughput

0.582

High

876187

PTSS2
Phosphatidylserine synthase 2

2

6

High-throughput

0.578

High

876146

HSDL2
Hydroxysteroid dehydrogenase-like protein 2

2

3

High-throughput

0.574

High

876175

INT12
Integrator complex subunit 12

2

4

High-throughput

0.574

High

359801

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

5

High-throughput

0.560

High

199312

ZW10
Centromere/kinetochore protein zw10 homolog

2

4

High-throughput

0.558

High

876101

GEMI4
Gem-associated protein 4

2

5

High-throughput

0.558

High

876140

RINT1
RAD50-interacting protein 1

2

8

High-throughput

0.558

High

179312

COPT2
Protein SLC31A2

1

1

High-throughput

0.541

High

330468

CLPT1
Putative lipid scramblase CLPTM1

1

8

High-throughput

0.541

High

385856

CPNS1
Calpain small subunit 1

1

4

High-throughput

0.541

High

446019

CD63
CD63 antigen

1

20

High-throughput

0.541

High

533135

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

3

High-throughput

0.541

High

572909

PRS6A
26S proteasome regulatory subunit 6A

1

7

High-throughput

0.541

High

588565

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

20

High-throughput

0.541

High

674126

HMOX2
Heme oxygenase 2

1

7

High-throughput

0.541

High

726108

BASI
Basigin

1

6

High-throughput

0.541

High

792900

SATT
Neutral amino acid transporter A

1

4

High-throughput

0.541

High

876102

CD81
CD81 antigen

1

20

High-throughput

0.541

High

876105

AT2C1
Calcium-transporting ATPase type 2C member 1

1

20

High-throughput

0.541

High

876110

ADCY2
Adenylate cyclase type 2

1

1

High-throughput

0.541

High

876111

ABCC8
ATP-binding cassette sub-family C member 8

1

2

High-throughput

0.541

High

876115

TMED1
Transmembrane emp24 domain-containing protein 1

1

7

High-throughput

0.541

High

876149

PRRT2
Proline-rich transmembrane protein 2

1

10

High-throughput

0.541

High

876174

LFG3
Protein lifeguard 3

1

5

High-throughput

0.541

High

876182

S39AD
Zinc transporter ZIP13

1

20

High-throughput

0.541

High

876193

S12A5
Solute carrier family 12 member 5

1

11

High-throughput

0.541

High

876194

PIGU
Phosphatidylinositol glycan anchor biosynthesis class U protein

1

4

High-throughput

0.541

High

876196

VIAAT
Vesicular inhibitory amino acid transporter

1

2

High-throughput

0.541

High

876200

RTN4
Reticulon-4

1

9

High-throughput

0.541

High

876212

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

4

High-throughput

0.541

High

876215

YIPF1
Protein YIPF1

1

11

High-throughput

0.541

High

206468

B4GA1
Beta-1,4-glucuronyltransferase 1

1

1

High-throughput

0.536

High

392664

B3A2
Anion exchange protein 2

1

6

High-throughput

0.536

High

415276

ATPB
ATP synthase subunit beta, mitochondrial

1

12

High-throughput

0.536

High

433299

YES
Tyrosine-protein kinase Yes

1

13

High-throughput

0.536

High

433665

LYN
Tyrosine-protein kinase Lyn

1

13

High-throughput

0.536

High

522872

SRC
Proto-oncogene tyrosine-protein kinase Src

1

13

High-throughput

0.536

High

530861

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

20

High-throughput

0.536

High

636867

ATPA
ATP synthase subunit alpha, mitochondrial

1

12

High-throughput

0.536

High

646151

STOM
Stomatin

1

6

High-throughput

0.536

High

871889

AT12A
Potassium-transporting ATPase alpha chain 2

1

20

High-throughput

0.536

High

871991

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

5

High-throughput

0.536

High

876106

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.536

High

876113

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

1

High-throughput

0.536

High

876114

S39A6
Zinc transporter ZIP6

1

20

High-throughput

0.536

High

876129

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

11

High-throughput

0.536

High

876135

CSCL2
CSC1-like protein 2

1

3

High-throughput

0.536

High

876137

RIF1
Telomere-associated protein RIF1

1

5

High-throughput

0.536

High

876144

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

13

High-throughput

0.536

High

876147

DYM
Dymeclin

1

8

High-throughput

0.536

High

876150

TMED4
Transmembrane emp24 domain-containing protein 4

1

6

High-throughput

0.536

High

876151

ZDH17
Palmitoyltransferase ZDHHC17

1

8

High-throughput

0.536

High

876162

GOGA5
Golgin subfamily A member 5

1

6

High-throughput

0.536

High

876164

CIP2A
Protein CIP2A

1

8

High-throughput

0.536

High

876169

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

15

High-throughput

0.536

High

876177

COQ8B
Atypical kinase COQ8B, mitochondrial

1

11

High-throughput

0.536

High

876180

TSN17
Tetraspanin-17

1

20

High-throughput

0.536

High

876184

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

1

High-throughput

0.536

High

876191

YIPF3
Protein YIPF3

1

7

High-throughput

0.536

High

876192

UN93B
Protein unc-93 homolog B1

1

3

High-throughput

0.536

High

100630

APRIO
Alternative prion protein

1

3

High-throughput

0.523

High

530239

ICAM2
Intercellular adhesion molecule 2

1

0

High-throughput

0.518

High

716637

CTNA1
Catenin alpha-1

1

0

High-throughput

0.518

High

876104

S35A1
CMP-sialic acid transporter

1

0

High-throughput

0.518

High

876156

LAT4
Large neutral amino acids transporter small subunit 4

1

0

High-throughput

0.518

High

236296

B4GT3
Beta-1,4-galactosyltransferase 3

1

0

High-throughput

0.513

High

245323

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.513

High

876168

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

378005

PRIO
Major prion protein

1

3

High-throughput

0.506

High

483784

HS71B
Heat shock 70 kDa protein 1B

1

1

High-throughput

0.506

High

213215

SNG2
Synaptogyrin-2

1

3

High-throughput

0.494

High

281582

WFS1
Wolframin

1

3

High-throughput

0.494

High

314581

CXB6
Gap junction beta-6 protein

1

12

High-throughput

0.494

High

622666

ERD21
ER lumen protein-retaining receptor 1

1

7

High-throughput

0.494

High

654206

CALX
Calnexin

1

6

High-throughput

0.494

High

876109

KLC1
Kinesin light chain 1

1

1

High-throughput

0.494

High

876117

MFS10
Major facilitator superfamily domain-containing protein 10

1

7

High-throughput

0.494

High

876120

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

1

High-throughput

0.494

High

876126

CNN3
Calponin-3

1

2

High-throughput

0.494

High

876128

RTN1
Reticulon-1

1

9

High-throughput

0.494

High

876133

PPM1J
Protein phosphatase 1J

1

1

High-throughput

0.494

High

876136

CXG2
Gap junction gamma-2 protein

1

12

High-throughput

0.494

High

876139

S18B1
MFS-type transporter SLC18B1

1

2

High-throughput

0.494

High

876158

NBPFF
Neuroblastoma breakpoint family member 15

1

1

High-throughput

0.494

High

876160

MORN4
MORN repeat-containing protein 4

1

5

High-throughput

0.494

High

876165

NAT14
Probable N-acetyltransferase 14

1

3

High-throughput

0.494

High

876166

PHLA1
Pleckstrin homology-like domain family A member 1

1

1

High-throughput

0.494

High

876178

YIPF6
Protein YIPF6

1

8

High-throughput

0.494

High

876201

OSTC
Oligosaccharyltransferase complex subunit OSTC

1

1

High-throughput

0.494

High

876205

T161A
Transmembrane protein 161A

1

6

High-throughput

0.494

High

610315

CBL
E3 ubiquitin-protein ligase CBL

1

0

Small-scale

0.493

High

155556

TNPO2
Transportin-2

1

18

High-throughput

0.489

High

163589

BTAF1
TATA-binding protein-associated factor 172

1

8

High-throughput

0.489

High

178136

IPO8
Importin-8

1

20

High-throughput

0.489

High

195899

TTI1
TELO2-interacting protein 1 homolog

1

4

High-throughput

0.489

High

237799

TSN3
Tetraspanin-3

1

20

High-throughput

0.489

High

279935

ATP5L
ATP synthase subunit g, mitochondrial

1

2

High-throughput

0.489

High

297166

IPO13
Importin-13

1

20

High-throughput

0.489

High

371271

ATP8
ATP synthase protein 8

1

2

High-throughput

0.489

High

579518

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

1

High-throughput

0.489

High

623234

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

1

5

High-throughput

0.489

High

735898

ATPG
ATP synthase subunit gamma, mitochondrial

1

4

High-throughput

0.489

High

777169

PEX19
Peroxisomal biogenesis factor 19

1

1

High-throughput

0.489

High

876100

SYJ2B
Synaptojanin-2-binding protein

1

20

High-throughput

0.489

High

876107

TAP1
Antigen peptide transporter 1

1

10

High-throughput

0.489

High

876123

OXA1L
Mitochondrial inner membrane protein OXA1L

1

3

High-throughput

0.489

High

876124

NOMO1
BOS complex subunit NOMO1

1

3

High-throughput

0.489

High

876132

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

19

High-throughput

0.489

High

876138

TBC9B
TBC1 domain family member 9B

1

9

High-throughput

0.489

High

876141

ARMC6
Armadillo repeat-containing protein 6

1

4

High-throughput

0.489

High

876142

BRAT1
BRCA1-associated ATM activator 1

1

6

High-throughput

0.489

High

876145

THADA
tRNA

1

7

High-throughput

0.489

High

876148

MON2
Protein MON2 homolog

1

20

High-throughput

0.489

High

876153

MIRO2
Mitochondrial Rho GTPase 2

1

17

High-throughput

0.489

High

876154

K2013
Uncharacterized protein KIAA2013

1

5

High-throughput

0.489

High

876155

INT1
Integrator complex subunit 1

1

9

High-throughput

0.489

High

876161

ATLA2
Atlastin-2

1

15

High-throughput

0.489

High

876163

TBC15
TBC1 domain family member 15

1

13

High-throughput

0.489

High

876170

GCN1
Stalled ribosome sensor GCN1

1

20

High-throughput

0.489

High

876172

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

20

High-throughput

0.489

High

876173

NCLN
BOS complex subunit NCLN

1

1

High-throughput

0.489

High

876176

F241B
Protein FAM241B

1

4

High-throughput

0.489

High

876179

HOOK2
Protein Hook homolog 2

1

8

High-throughput

0.489

High

876181

RUSF1
RUS family member 1

1

4

High-throughput

0.489

High

876183

CP2S1
Cytochrome P450 2S1

1

3

High-throughput

0.489

High

876188

FACD2
Fanconi anemia group D2 protein

1

9

High-throughput

0.489

High

876190

XPO4
Exportin-4

1

20

High-throughput

0.489

High

876195

HEAT1
HEAT repeat-containing protein 1

1

6

High-throughput

0.489

High

876197

AT133
Polyamine-transporting ATPase 13A3

1

20

High-throughput

0.489

High

876198

COG4
Conserved oligomeric Golgi complex subunit 4

1

5

High-throughput

0.489

High

876199

XPO5
Exportin-5

1

20

High-throughput

0.489

High

876202

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

7

High-throughput

0.489

High

876203

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

1

High-throughput

0.489

High

876204

FANCI
Fanconi anemia group I protein

1

2

High-throughput

0.489

High

876207

CS025
UPF0449 protein C19orf25

1

4

High-throughput

0.489

High

876208

IPO11
Importin-11

1

20

High-throughput

0.489

High

876211

TMCO1
Calcium load-activated calcium channel

1

5

High-throughput

0.489

High

876214

TELO2
Telomere length regulation protein TEL2 homolog

1

4

High-throughput

0.489

High

876216

TNPO3
Transportin-3

1

20

High-throughput

0.489

High

876217

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

6

High-throughput

0.489

High

120141

TLR4
Toll-like receptor 4

1

1

Small-scale

0.479

High

270277

LRP6
Low-density lipoprotein receptor-related protein 6

1

1

Small-scale

0.479

High

764612

CUX1
Homeobox protein cut-like 1

1

8

High-throughput

0.479

High

833188

TMEDA
Transmembrane emp24 domain-containing protein 10

1

6

Small-scale

0.479

High

876131

Q4LE69
1-phosphatidylinositol 4-kinase

1

17

High-throughput

0.479

High

532870

TF
Tissue factor

1

0

Small-scale

0.458

High

876118

Q14868
Effector cell protease receptor 1

1

0

Small-scale

0.458

High

787637

PI4KA
Phosphatidylinositol 4-kinase alpha

1

19

High-throughput

0.445

High

876116

CASP
Protein CASP

1

8

High-throughput

0.445

High

177662

BIRC5
Baculoviral IAP repeat-containing protein 5

1

1

Small-scale

0.437

High

876134

GASP1
G-protein coupled receptor-associated sorting protein 1

1

6

Small-scale

0.437

High

876167

GEMI6
Gem-associated protein 6

1

1

High-throughput

0.437

High

146906

DHSD
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

1

0

High-throughput

0.282

High

876112

TMM62
Transmembrane protein 62

1

0

High-throughput

0.282

High

876121

R3HD1
R3H domain-containing protein 1

1

0

High-throughput

0.282

High

876122

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.282

High

876130

QSER1
Glutamine and serine-rich protein 1

1

0

High-throughput

0.282

High

876186

ABHEA
Protein ABHD14A

1

0

High-throughput

0.282

High

876206

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

High-throughput

0.282

High

876209

CRLS1
Cardiolipin synthase

1

0

High-throughput

0.282

High

876127

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.279

Low

876143

OGFD3
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

1

0

High-throughput

0.279

Low

876152

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.279

Low

876157

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

876159

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

0

High-throughput

0.279

Low

876185

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.279

Low

876189

UCK2
Uridine-cytidine kinase 2

1

0

High-throughput

0.279

Low

876210

DNM3L
DNA

1

0

Small-scale

0.261

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024