Protein: IF4G2
Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Death-associated protein 5) (DAP-5) (p97)

Gene: IF4G2, EIF4G2
Organism: Homo sapiens
Interactions: 131
UniProt ID: P78344

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005912 - adherens junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

892776

IF4A1
Eukaryotic initiation factor 4A-I

9

20

Small-scale

0.975

High

941985

IF4A2
Eukaryotic initiation factor 4A-II

3

20

Small-scale

0.839

High

942002

DDX60
Probable ATP-dependent RNA helicase DDX60

1

3

High-throughput

0.691

High

941989

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

3

1

High-throughput

0.667

High

133973

DDX3X
ATP-dependent RNA helicase DDX3X

1

4

High-throughput

0.618

High

294689

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.618

High

941977

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

5

High-throughput

0.618

High

941987

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

5

High-throughput

0.618

High

795616

MAGA1
Melanoma-associated antigen 1

3

5

High-throughput

0.609

High

496828

TAU
Microtubule-associated protein tau

2

2

High-throughput

0.601

High

942008

SERB1
SERPINE1 mRNA-binding protein 1

2

0

High-throughput

0.585

High

227140

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.584

High

338271

EGFR
Epidermal growth factor receptor

2

3

High-throughput

0.584

High

416966

IF4E
Eukaryotic translation initiation factor 4E

2

18

Small-scale

0.584

High

503878

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.584

High

668588

PML
Protein PML

2

3

High-throughput

0.584

High

779221

CCNF
Cyclin-F

2

4

High-throughput

0.584

High

388373

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.582

High

369374

ESR1
Estrogen receptor

2

8

High-throughput

0.571

High

942006

NGEF
Ephexin-1

2

3

High-throughput

0.571

High

865029

TTC3
E3 ubiquitin-protein ligase TTC3

1

11

High-throughput

0.541

High

323683

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

380277

HG2A
HLA class II histocompatibility antigen gamma chain

1

2

High-throughput

0.536

High

418163

NPM
Nucleophosmin

1

3

High-throughput

0.536

High

501967

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.536

High

574300

RL35A
Large ribosomal subunit protein eL33

1

1

High-throughput

0.536

High

586678

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.536

High

611231

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

2

High-throughput

0.536

High

840936

MAP2
Methionine aminopeptidase 2

1

2

High-throughput

0.536

High

879226

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

11

High-throughput

0.536

High

941978

TRAF2
TNF receptor-associated factor 2

1

2

High-throughput

0.536

High

942016

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

942035

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

2

High-throughput

0.536

High

552478

RFA2
Replication protein A 32 kDa subunit

2

5

High-throughput

0.535

High

588877

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

5

Small-scale

0.534

High

795853

MAGA6
Melanoma-associated antigen 6

1

5

High-throughput

0.515

High

942023

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

5

Small-scale

0.515

High

257978

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

941980

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

942015

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

942020

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

174798

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

6

High-throughput

0.501

High

902516

SUMO2
Small ubiquitin-related modifier 2

1

7

High-throughput

0.501

High

941974

HTRA4
Serine protease HTRA4

1

2

High-throughput

0.489

High

942004

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

942033

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.489

High

521342

SKIL
Ski-like protein

1

0

High-throughput

0.486

High

942013

CBP
CREB-binding protein

1

4

Small-scale

0.481

High

124832

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

5

High-throughput

0.479

High

125361

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

5

High-throughput

0.479

High

148666

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.479

High

162623

XPO1
Exportin-1

1

7

High-throughput

0.479

High

176999

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

6

High-throughput

0.479

High

232839

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

6

High-throughput

0.479

High

276013

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

1

Small-scale

0.479

High

278779

DNJC8
DnaJ homolog subfamily C member 8

1

1

High-throughput

0.479

High

350060

RASK
GTPase KRas

1

3

High-throughput

0.479

High

363062

FINC
Fibronectin

1

2

High-throughput

0.479

High

384635

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.479

High

398686

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

3

Small-scale

0.479

High

417231

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

455316

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

521860

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

530617

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

684625

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.479

High

841647

CDK9
Cyclin-dependent kinase 9

1

4

High-throughput

0.479

High

874817

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

892993

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

917096

H4
Histone H4

1

3

High-throughput

0.479

High

934084

CSK21
Casein kinase II subunit alpha

1

9

Small-scale

0.479

High

941976

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

941979

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

2

High-throughput

0.479

High

941981

G3BP1
Ras GTPase-activating protein-binding protein 1

1

6

High-throughput

0.479

High

941982

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

941984

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

9

Small-scale

0.479

High

941988

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

941990

PCBP1
Poly(rC)-binding protein 1

1

6

Small-scale

0.479

High

941991

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.479

High

941992

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

941996

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

3

High-throughput

0.479

High

941998

YTHD3
YTH domain-containing family protein 3

1

2

High-throughput

0.479

High

942000

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

942009

NUP43
Nucleoporin Nup43

1

7

High-throughput

0.479

High

942010

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.479

High

942012

HDAC2
Histone deacetylase 2

1

5

High-throughput

0.479

High

942018

OPTN
Optineurin

1

4

High-throughput

0.479

High

942024

RN126
E3 ubiquitin-protein ligase RNF126

1

1

High-throughput

0.479

High

942025

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

942027

RC3H2
Roquin-2

1

4

High-throughput

0.479

High

942028

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

Small-scale

0.479

High

942029

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

942031

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

942032

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

942034

FZR1
Fizzy-related protein homolog

1

7

High-throughput

0.479

High

942037

YTHD2
YTH domain-containing family protein 2

1

2

High-throughput

0.479

High

941975

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

941999

EST1A
Telomerase-binding protein EST1A

1

0

High-throughput

0.458

High

942003

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.458

High

942030

ZO2
Tight junction protein ZO-2

1

0

High-throughput

0.458

High

942036

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.458

High

321048

PTBP3
Polypyrimidine tract-binding protein 3

1

8

High-throughput

0.445

High

882233

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.445

High

941983

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.445

High

942022

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.445

High

100671

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

244269

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.437

High

260546

TP4A3
Protein tyrosine phosphatase type IVA 3

1

1

High-throughput

0.437

High

282877

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

2

High-throughput

0.437

High

312050

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

1

Small-scale

0.437

High

346491

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.437

High

650936

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

720215

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

832361

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.437

High

941993

LMBRL
Protein LMBR1L

1

4

High-throughput

0.437

High

941994

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

941995

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.437

High

941997

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

942001

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.437

High

942011

ESR2
Estrogen receptor beta

1

8

High-throughput

0.437

High

942026

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

941986

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

831205

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

581667

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.407

High

388869

CP1A1
Cytochrome P450 1A1

3

0

High-throughput

0.347

High

473753

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

0

High-throughput

0.282

High

942021

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

942007

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

942014

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.279

Low

942017

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

High-throughput

0.279

Low

942019

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

942005

NIN
Ninein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024